The Caryāpadas: its language and religious meaning

This work aims to provide an overview of topic through the summary of available secondary literature. The discussed topic is one thousand years old Bengali religious songs. About fifty of these songs were discovered one hundred years ago in a Nepalese archive. Authors of the songs were mostly Buddhist laymen and masters from the area of nowadays Bangladesh and West Bengal. These songs are considered by scholars to be the oldest specimen of literature written in Bengali language although this pre-eminent position is claimed by closely related Indo-Aryan languages like Assamese, Bihari and Oriya too. Beside the philological aspect we are concerned with a particular coded language used in these songs. Then we discuss their content and spiritual meaning and we place the ideas they express into wider religious context

Additional file 4: of Towards a functional hypothesis relating anti-islet cell autoimmunity to the dietary impact on microbial communities and butyrate production

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Epigenome–wide Meta–Analysis Reveals Associations between Dietary Glycemic Index and Glycemic Load and DNA methylation in Children and Adolescents with Different Body Size

Objective: Dietary glycemic index (GI) and glycemic load (GL) are associated with cardio–metabolic health in children and adolescents, with potential distinct effects in people with increased body mass index (BMI). DNA methylation (DNAm) may mediate these effects. Thus, we conducted meta–analyses of epigenome–wide association studies (EWASs) between dietary GI and GL and blood DNAm of children and adolescents.Research Design and Methods: We calculated dietary GI and GL and performed EWASs in children and adolescents (age range: 4.5–17 years) from six cohorts (ntotal = 1,187). We performed stratified analyses of participants with normal–weight (ntotal = 801) or overweight/obesity (ntotal = 386). We performed look–ups for the identified cytosine–phosphate–guanine (CpG) sites (false discovery rate (FDR) Results: Dietary GL was positively associated with DNAm of cg20274553 (FDR Conclusions: We identified 537 associations between dietary GI and GL and blood DNAm, mainly in children and adolescents with overweight/obesity. High GI and/or GL diets may influence epigenetic gene regulation and thereby, promote metabolic derangements in young persons with increased BMI.</p