FERAL SWINE---ARE THEY A DISEASE THREAT TO LIVESTOCK IN THE UNITED STATES?

Feral swine populations provide both benefits and liabilities to citizens of the United States. Their expanding range and increasing densities, however, have raised concern over the adverse environmental and agricultural effects and the increased risk of disease transmission between feral swine and livestock. We discuss the role of feral swine in the transmission of wildlife diseases and, in particular, in diseases of national significance to the livestock industry. We also discuss available management tools and strategies for reducing feral swine populations, minimizing damage or disease occurrences and eradicating populations when deemed appropriate. Finally, we note areas of research that may provide valuable management tools in the future

Simulation, modelling and development of the metris RCA

In partnership with Metris UK we discuss the utilisation of modelling and simulation methods in the development of a revolutionary 7-axis Robot CMM Arm (RCA). An offline virtual model is described, facilitating pre-emptive collision avoidance and assessment of optimal placement of the RCA relative to scan specimens. Workspace accessibility of the RCA is examined under a range of geometrical assumptions and we discuss the effects of arbitrary offsets resulting from manufacturing tolerances. Degeneracy is identified in the number of ways a given pose may be attained and it is demonstrated how a simplified model may be exploited to solve the inverse kinematics problem of finding the “correct” set of joint angles. We demonstrate how the seventh axis may be utilised to avoid obstacles or otherwise awkward poses, giving the unit greater dexterity than traditional CMMs. The results of finite element analysis and static force modelling on the RCA are presented which provide an estimate of the forces exerted on the internal measurement arm in a range of poses

Dangling-bond charge qubit on a silicon surface

Two closely spaced dangling bonds positioned on a silicon surface and sharing an excess electron are revealed to be a strong candidate for a charge qubit. Based on our study of the coherent dynamics of this qubit, its extremely high tunneling rate ~ 10^14 1/s greatly exceeds the expected decoherence rates for a silicon-based system, thereby overcoming a critical obstacle of charge qubit quantum computing. We investigate possible configurations of dangling bond qubits for quantum computing devices. A first-order analysis of coherent dynamics of dangling bonds shows promise in this respect.Comment: 17 pages, 3 EPS figures, 1 tabl

EIS Then and Now Tracking the Human-Suit Interface

No abstract availabl

Characteristics, accuracy and reverification of robotised articulated arm CMMs

VDI article 2617 specifies characteristics to describe the accuracy of articulated arm coordinate measuring machines (AACMMs) and outlines procedures for checking them. However the VDI prescription was written with a former generation of machines in mind: manual arms exploiting traditional touch probe technologies. Recent advances in metrology have given rise to noncontact laser scanning tools and robotic automation of articulated arms – technologies which are not adequately characterised using the VDI specification. In this paper we examine the “guidelines” presented in VDI 2617, finding many of them to be ambiguous and open to interpretation, with some tests appearing even to be optional. The engineer is left significant flexibility in the execution of the test procedures and the manufacturer is free to specify many of the test parameters. Such flexibility renders the VDI tests of limited value and the results can be misleading. We illustrate, with examples using the Nikon RCA, how a liberal interpretation of the VDI guidelines can significantly improve accuracy characterisation and suggest ways in which to mitigate this problem. We propose a series of stringent tests and revised definitions, in the same vein as VDI 2617 and similar US standards, to clarify the accuracy characterisation process. The revised methodology includes modified acceptance and reverification tests which aim to accommodate emerging technologies, laser scanning devices in particular, while maintaining the spirit of the existing and established standards. We seek to supply robust re-definitions for the accepted terms “zero point” and “useful arm length”, pre-supposing nothing about the geometry of the measuring device. We also identify a source of error unique to robotised AACMMs employing laser scanners – the forward-reverse pass error. We show how eliminating this error significantly improves the repeatability of a device and propose a novel approach to the testing of probing error based on statistical uncertainty

The "Space Activity Suit" - A Historical Perspective and A Primer on the Physiology of Mechanical Counter-Pressure

Since the 1950s, mechanical counter-pressure (MCP) has been investigated as a possible alternative design concept to traditional extra-vehicular activity (EVA) space suits. While traditional gas-pressurized EVA suits provide physiological protection against the ambient vacuum by means of pressurized oxygen to at least 3.1 pounds per square inch absolute (160 millimeters of mercury), MCP provides protection by direct application of pressure on the skin by a fabric. In reviewing the concept, MCP offers distinct potential advantages to traditional EVA suits: lower mass, reduced consumables, increased mobility, increased comfort, less complexity, and improved failure modes. In the mid 1960s to early 1970s, Dr. Paul Webb of Webb Associates developed and tested such a suit under funding from NASA Langley Research Center. This "Space Activity Suit" (SAS) was improved many times while testing in the laboratory and an altitude chamber to as low as 0.3 pounds per square inch absolute (15 millimeters of mercury). This testing, and the reports by Webb documenting it, are often presented as evidence of the feasibility of MCP. In addition, the SAS reports contain a wealth of information regarding the physiological requirements to make MCP work at the time, which is still accurate today. This paper serves to document the Space Activity Suit effort and analyze it in today's context

Transonic airframe propulsion integration

This chart shows the time line for HSR propulsion/airframe integration program. HSR Phase 1 efforts are underway in both propulsion and aerodynamics. The propulsion efforts focus on cycles, inlets combustors and nozzles that will be required to reduce nitrogen oxide (NOX) at cruise and noise at takeoff and landing to acceptable levels. The aerodynamic efforts concentrate on concepts that will reduce sonic booms and increase the lift/drag (L/D) ratio for the aircraft. The Phase 2 critical propulsion component technology program will focus on large scale demonstrators of the inlet, fan, combustor, and nozzle. The hardware developed here will feed into the propulsion system program which will demonstrate overall system technology readiness, particularly in the takeoff and supersonic cruise speed ranges. The Phase 2 aerodynamic performance and vehicle integration program will provide a validated data base for advanced airframe/control/integration concepts over the full HSR speed range. The results of this program will also feed into the propulsion system demonstration program, particularly in the critical transonic arena

Effect of urinary pH and diatrizoate on Bence Jones protein nephrotoxicity in the rat

Effect of urinary pH and diatrizoate on Bence Jones protein nephrotoxicity in the rat. Both low urinary pH and radiocontrast agents may intensify myeloma nephrotoxicity. To study the effects of these factors, we determined inulin clearances (CIn) before and after infusions of human Bence Jones protein (BJP) in male Sprague-Dawley rats in a dose previously shown to be nephrotoxic. Rats that drank 0.15 M NaHCO3 for 48 hr before study had no change in CIn (+ 3 ± 20%) after BJP unlike those that drank 0.15 M NH4Cl (- 33 ± 14%, P < 0.05); urinary pH differed (7.6 ± 0.1 vs. 6.2 ± 0.1, P < 0.05), but urinary flow rates did not. The acidifying regimen was used in all subsequent groups. Infusion of diatrizoate (DTZ) after BJP produced a further decrease in CIn (- 85 ± 8%, P < 0.05). In contrast, infusion of albumin, which raised plasma protein concentration to that seen in BJP-infused rats, did not change CIn (+ 39 ± 17%). Infusion of beta-lactoglobulin also led to a greater decrease in CIn after DTZ (- 35 ± 9 vs. - 67 ± 8%, P < 0.05), but myoglobin did not (- 58 ± 7 vs. - 54 ± 12%). Urinary pH and flow rate did not differ between any DTZ-infused group and its appropriate control. These data suggest that aciduria independent of urinary flow rate increases the nephrotoxicity of BJP. In this setting, DTZ further intensifies the nephrotoxicity of BJP as well as some but not all filterable proteins.Effet du pH urinaire et du diatrizoate sur la néphrotoxicité de la protéine de Bence Jones chez le rat. Un pH urinaire bas et les produits de contraste peuvent accroître la néphrotoxité du myélome. Pour étudier les effets de ces facteurs, nous avons déterminé les clearances de l'inuline (CIn) avant et après perfusion de protéine de Bence Jones humaine (BJP) chez des rats mâles Sprague-Dawley à dose préalablement montrée néphrotoxique. Les rats qui buvaient 0,15 M NaHCO3 pendant 48 hr avant l'étude n'avaient pas de modification de CIn (+ 3 ± 20%) après BJP à la différence de ceux qui buvaient 0,15 M NH4Cl (- 33 ± 14%, P < 0,05); les pH urinaires différaient (7,6 ± 0,1 contre 6,2 ± 0,1, P < 0,05), mais non les débits urinaires. Le régime acidifiant a été utilisé chez tous les groupes ultérieurs. La perfusion de diatrizoate (DTZ) après BJP a entraîné une diminution supplémentaire de CIn (- 85 ± 8%, P < 0,05). A l'opposé une perfusion d'albumine, qui augmentait la protidémie à la valeur observée chez les rats perfusés avec BJP ne modifiait pas CIn (+ 39 ± 17%). Une perfusion de béta-lactoglobuline a également entraîné une plus forte baisse de CIn après DTZ (- 35 ± 9 contre - 67 ± 8%, P < 0,05), mais non de la myoglobine (- 58 ± 7 contre - 54 ± 12%). Le pH et le débit urinaires ne différaient pas entre aucun des groupes perfusés par le DTZ et leur contrôle approprié. Ces données suggèrent que l'acidurie, indépendamment du débit urinaire, augmente la néphrotoxicité de la BJP. Dans ce schéma, DTZ accentue encore la néphrotoxicité de la BJP, de même que certaines, mais non toutes les protéines filtrables

Diversity of microbial eukaryotes along the West Antarctic Peninsula in austral spring

© The Author(s), 2022. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Grattepanche, J.-D., Jeffrey, W., Gast, R., & Sanders, R. Diversity of microbial eukaryotes along the West Antarctic Peninsula in austral spring. Frontiers in Microbiology, 13, (2022): 844856, https://doi.org/10.3389/fmicb.2022.844856.During a cruise from October to November 2019, along the West Antarctic Peninsula, between 64.32 and 68.37°S, we assessed the diversity and composition of the active microbial eukaryotic community within three size fractions: micro- (> 20 μm), nano- (20–5 μm), and pico-size fractions (5–0.2 μm). The communities and the environmental parameters displayed latitudinal gradients, and we observed a strong similarity in the microbial eukaryotic communities as well as the environmental parameters between the sub-surface and the deep chlorophyll maximum (DCM) depths. Chlorophyll concentrations were low, and the mixed layer was shallow for most of the 17 stations sampled. The richness of the microplankton was higher in Marguerite Bay (our southernmost stations), compared to more northern stations, while the diversity for the nano- and pico-plankton was relatively stable across latitude. The microplankton communities were dominated by autotrophs, mostly diatoms, while mixotrophs (phototrophs-consuming bacteria and kleptoplastidic ciliates, mostly alveolates, and cryptophytes) were the most abundant and active members of the nano- and picoplankton communities. While phototrophy was the dominant trophic mode, heterotrophy (mixotrophy, phagotrophy, and parasitism) tended to increase southward. The samples from Marguerite Bay showed a distinct community with a high diversity of nanoplankton predators, including spirotrich ciliates, and dinoflagellates, while cryptophytes were observed elsewhere. Some lineages were significantly related—either positively or negatively—to ice coverage (e.g., positive for Pelagophyceae, negative for Spirotrichea) and temperature (e.g., positive for Cryptophyceae, negative for Spirotrichea). This suggests that climate changes will have a strong impact on the microbial eukaryotic community.This work was supported by the National Science Foundation (Grant Nos. ANT 1744767 to RS, ANT 1744663 to RG, and ANT 1744638 to WJ). This research was based, in part, upon sequencing conducted using the Rhode Island Genomics and Sequencing Center, which was supported in part by the National Science Foundation (MRI Grant No. DBI-0215393 and EPSCoR Grant Nos. 0554548 and EPS-1004057), the US Department of Agriculture (Grant Nos. 2002-34438-12688 and 2003-34438-13111), and the University of Rhode Island. This research includes calculations carried out on Temple University HPC resources supported in part by the National Science Foundation through major research instrumentation (Grant No. 1625061) and by the US Army Research Laboratory under (Contract No. W911NF-16-2-0189)