566 research outputs found

    PRODUCER ACCEPTANCE OF A NEW PEANUT MARKETING COOPERATIVE: A SURVEY OF GEORGIA PEANUT PRODUCERS

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    Market conduct has become an important issue for peanut farmers. Consolidation in the first buyer market, increased imports, and political uncertainty have increased peanut producers' marketing risks. The purpose of this paper was to examine demographic differences in peanut producers' perceptions of the current marketing environment as well as their attitudes towards new marketing institutions. A standard t-test revealed that producers growing more than 250 acres of peanuts, irrigating at least 50 percent of their peanuts, and producers located in Southwest Georgia were statistically more dissatisfied with the current marketing environment and significantly more receptive to forming a new generation peanut cooperative.Agribusiness, Crop Production/Industries,

    A NEW GENERATION PEANUT COOPERATIVE IN GEORGIA: A BENEFIT-COST ANALYSIS

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    A survey of Georgia peanut producers revealed that the Southwest corner of Georgia could be targeted for a new generation peanut cooperative (FS 01-07). The objective of this study was to examine the feasibility of this option. Preliminary results revealed that this might be an economically feasible solution to peanut producers' marketing problems. The projected discounted benefit-cost ratios ranged from 1.9 to 1.4 over a ten-year period.Agribusiness, Crop Production/Industries,

    Insights into spatial inhomogeneity in an oxygen plasma from cavity ringdown spectroscopy

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    Cavity ringdown spectroscopy has been used to investigate the translational and rotational temperatures of theĀ vĀ = 0 and 1 vibrational levels of O2(X) in an inductively coupled plasma at 100 mTorr (13.332 Pa) pressure. All rotational states probed display a clear increase in temperature as plasma power increases: at fixed power, the translational temperature appears largest for rotational states inĀ vĀ = 1 (J= 7, 16, 17, 22) and lowest in the low energy states (JĀ = 1, 18, 19) inĀ vĀ = 0; highly excited rotational states (JĀ = 28, 30, 31) ofĀ vĀ = 0 show intermediate behaviour. The rotational temperature values behave similarly. These observations are consistent with the effects of plasma inhomogeneity and can be interpreted with a simple one-dimensional model whereby the pressure, temperature and mole fractions of the various species across the chamber (and arms) are approximated with rational profiles and the corresponding line-of-sight averaged densities and temperatures calculated. This basic model is reasonably successful at reproducing the observations for O2(X,Ā vĀ = 0) and O(3P) densities. The fact that resolving several rotational transitions allows spatial variations within the plasma to be inferred from line-of-sight averaged measurements is an extremely powerful result that could be of great utility in future work

    Targeting the Pseudomonas aeruginosa Virulence Factor Phospholipase C With Engineered Liposomes.

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    Engineered liposomes composed of the naturally occurring lipids sphingomyelin (Sm) and cholesterol (Ch) have been demonstrated to efficiently neutralize toxins secreted by Gram-positive bacteria such as Streptococcus pneumoniae and Staphylococcus aureus. Here, we hypothesized that liposomes are capable of neutralizing cytolytic virulence factors secreted by the Gram-negative pathogen Pseudomonas aeruginosa. We used the highly virulent cystic fibrosis P. aeruginosa Liverpool Epidemic Strain LESB58 and showed that sphingomyelin (Sm) and a combination of sphingomyelin with cholesterol (Ch:Sm; 66ā€‰mol/% Ch and 34ā€‰mol/% Sm) liposomes reduced lysis of human bronchial and red blood cells upon challenge with the Pseudomonas secretome. Mass spectrometry of liposome-sequestered Pseudomonas proteins identified the virulence-promoting hemolytic phospholipase C (PlcH) as having been neutralized. Pseudomonas aeruginosa supernatants incubated with liposomes demonstrated reduced PlcH activity as assessed by the p-nitrophenylphosphorylcholine (NPPC) assay. Testing the in vivo efficacy of the liposomes in a murine cutaneous abscess model revealed that Sm and Ch:Sm, as single dose treatments, attenuated abscesses by >30%, demonstrating a similar effect to that of a mutant lacking plcH in this infection model. Thus, sphingomyelin-containing liposome therapy offers an interesting approach to treat and reduce virulence of complex infections caused by P. aeruginosa and potentially other Gram-negative pathogens expressing PlcH

    Activated mutant NRasQ61K drives aberrant melanocyte signaling, survival, and invasiveness via a rac1-Dependent mechanism

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    Around a fifth of melanomas exhibit an activating mutation in the oncogene NRas that confers constitutive signaling to proliferation and promotes tumor initiation. NRas signals downstream of the major melanocyte tyrosine kinase receptor c-kit and activated NRas results in increased signaling via the extracellular signalā€“regulated kinase (ERK)/MAPK/ERK kinase/mitogen-activated protein kinase (MAPK) pathways to enhance proliferation. The Ras oncogene also activates signaling via the related Rho GTPase Rac1, which can mediate growth, survival, and motility signaling. We tested the effects of activated NRasQ61K on the proliferation, motility, and invasiveness of melanoblasts and melanocytes in the developing mouse and ex vivo explant culture as well as in a melanoma transplant model. We find an important role for Rac1 downstream of NRasQ61K in mediating dermal melanocyte survival in vivo in mouse, but surprisingly NRasQ61K does not appear to affect melanoblast motility or proliferation during mouse embryogenesis. We also show that genetic deletion or pharmacological inhibition of Rac1 in NRasQ61K induced melanoma suppresses tumor growth, lymph node spread, and tumor cell invasiveness, suggesting a potential value for Rac1 as a therapeutic target for activated NRas-driven tumor growth and invasiveness

    Cavity ringdown studies of the Eā€“H transition in an inductively coupled oxygen plasma: comparison of spectroscopic measurements and modelling

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    The absolute number density of ground state oxygen atoms, O(3P), present in a 100 mTorr oxygen plasma has been determined as a function of operating power using cavity ringdown spectroscopy (CRDS). The dissociation fraction increases by an order of magnitude from āˆ¼0.8% at 50 W to 8% at 250 W and reflects a similar increase in the electron density over this power range. Emission spectra show that the Eā€“H switchover is accompanied by increased rotational heating of O2 and this behaviour is also observed in the translational temperatures determined by fitting the Doppler limited O(3P) CRDS data. The measurements are contextualised via a volume averaged kinetic model that uses the measured absolute densities of O(3P) and O2(a1Ī”g, v = 0) as a function of power as its benchmarks. Despite the inherent spatial inhomogeneity of the plasma, the volume averaged model, which uses a minimal set of reactions, is able to both reproduce previous measurements on the absolute density of Oāˆ’ and to infer physically reasonable values for both the electron temperature and number density as the Eā€“H switch over is traversed. Time-resolved emission measurements return a value of 0.2 for the wall loss coefficient for O2(b1Ī£g+); as a consequence, the number density of O2(b1Ī£g+) is (at least) one order of magnitude less than O2(a1Ī”g)

    Independent discovery of a nulling pulsar with unusual subpulse drifting properties with the Murchison Widefield Array

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    We report the independent discovery of PSR J0026-1955 with the Murchison Widefield Array (MWA) in the ongoing Southern-sky MWA Rapid Two-metre pulsar survey. J0026-1955 has a period of āˆ¼1.306 s, a dispersion measure of āˆ¼20.869 pc cm-3, and a nulling fraction of āˆ¼77%. This pulsar highlights the advantages of the survey's long dwell times (āˆ¼80 minutes), which, when fully searched, will be sensitive to the expected population of similarly bright, intermittent pulsars with long nulls. A single-pulse analysis in the MWA's 140-170 MHz band also reveals a complex subpulse drifting behavior, including both rapid changes of the drift rate characteristic of mode switching pulsars, as well as a slow, consistent evolution of the drift rate within modes. In some longer drift sequences, interruptions in the otherwise smooth drift rate evolution occur preferentially at a particular phase, typically lasting a few pulses. These properties make this pulsar an ideal test bed for prevailing models of drifting behavior such as the carousel model
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