128 research outputs found

    Some Numerical Characteristics of Image Texture

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    Texture classification is one of the basic images processing tasks. In this paper we present some numerical characteristics to the images analysis and processing. It can be used at the solving of images classification problems, their recognition, problems of remote sounding, biomedical images analysis, geological researches

    Dipole moments and conformations of 2-(4-pyridyl)ethyl alkyl(aryl) sulfides

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    Study of the 2-(4-pyridyl)ethyl akyl sulfides has shown that these compounds exist as equilibrated mixtures of structures with trans- and gauche-oriented C-Py and C-S fragments, the content of the first making up 0.6-0.7 fraction of the whole. © 1977 Plenum Publishing Corporation

    Dipole moments and conformations of 2-(4-pyridyl)ethyl alkyl(aryl) sulfides

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    Study of the 2-(4-pyridyl)ethyl akyl sulfides has shown that these compounds exist as equilibrated mixtures of structures with trans- and gauche-oriented C-Py and C-S fragments, the content of the first making up 0.6-0.7 fraction of the whole. © 1977 Plenum Publishing Corporation

    Dipole moments of organophosphorus compounds. 16. Conformations of trimethylsilyl groups in some phosphites, phosphates, and phosphonates

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    1. A study has been made of the dipole moments, Kerr constants, and IR spectra of silicon-containing phosphites, phosphates, and phosphonates. 2. The silicon-containing phosphates and phosphonates exist as equilibrium mixtures of various conformers, the predominant form being that in which the P=0 (S, Se) and (CH3)3SiO groups are in cis orientation. 3. The trimethylsilyl group preferentially occupies a gauche position with respect to the unshared electron pair of the phosphorus atom in compounds containing phosphorus in three-coordination. © 1978 Plenum Publishing Corporation

    Anisotropy of polarizability of the silatranes

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    1. Polarizability parameters have been determined for the Si-C and Si-O bonds. The Si-O bond of the siloxanes does not show axial symmetry. 2. The axes of the molecular polarizability ellipsoid for 1-methylsilatrane have been determined. 3. The transannular N → Si bond shows a pronounced anisotropy of polarizability in the silatranes. © 1977 Plenum Publishing Corporation

    Influence of the child's genotype features on the course and prognosis of essential arterial hypertension. Clinical case

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    Clinical case of early diagnostics of essential arterial hypertension in a 6-year-old child, which is described in the article, shows that comprehensive medical examination in patients with persistent high blood pressure is required. Identification of genetic polymorphisms of arterial hypertension should be done to exclude secondary hypertension and define possible reasons for resistance to drug therapy and prognosis for the disease.На клиническом примере раннего дебюта эссенциальной артериальной гипертензии (АГ) у шестилетнего ребенка показана необходимость комплексного обследования пациентов со стойко повышенным артериальным давлением, включая генетическое обследование на полиморфизм генов АГ, позволяющего исключить вторичный генез артериальной гипертензии, определить вероятные причины резистентности к проводимой терапии и прогноз течения заболевания

    Comparative analysis of gene expression in tea plant (Camellia sinensis (L.) Kuntze) under low-temperature stress

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    Low-temperature stress is one of the main factors limiting the distribution and reducing the yield of many subtropical crops, including the tea crop. Efficient breeding to develop frost-tolerant cultivars requires a reliable set of genetic markers for identifying resistance donors, and that is why it is necessary to reveal the specific genetic response in frost-tolerant genotypes in comparison with frost- susceptible ones. In this work, we performed a comparative analysis of the expression of 18 tea genes (ICE1, CBF1, DHN1, DHN2, DHN3, NAC17, NAC26, NAC30, bHLH7, bHLH43, P5CS, WRKY2, LOX1, LOX6, LOX7, SnRK1.1, SnRK1.2, SnRK1.3) under cold and frost conditions in two tea genotypes, tolerant and susceptible. Low-temperature stress was induced by placing the potted plants in cold chambers and lowering the temperature to 0…+2 °С for 7 days (cold stress), followed by a decrease in temperature to –4…–6 °С for 5 days (frost stress). Relative electrical conductivity of leaf was measured in response to the stress treatments, and a significant difference in the frost tolerance of the two tea genotypes was confirmed. Cold exposure did not lead to a change in the electrical conductivity of leaf tissue. On the other hand, frost treatment resulted in increased REC in both genotypes and to a greater extent in the susceptible genotype. Increased expression of all the genes was shown during cold and frost. The genes that were strongly expressed in the tolerant tea genotype were revealed: ICE1, CBF1, DHN2, NAC17, NAC26, bHLH43, WRKY2, P5CS, LOX6, SnRK1.1, SnRK1.3. These genes can be proposed as markers for the selection of frost-tolerance donors in tea germplasm collections. Additionally, it was shown that the tolerant genotype is characterized by an earlier response to stress at the stage of cold acclimation. The study of the expression of the identified genes in different organs of tea plants and in different exposures to low temperature is relevant for further investigations

    СОВРЕМЕННЫЕ АСПЕКТЫ ПРОФИЛАКТИКИ ПЕРИНАТАЛЬНОЙ ПЕРЕДАЧИ ВИЧ В САНКТ-ПЕТЕРБУРГЕ

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    Saint-Petersburg is among the leaders in medical treatment of HIV-positive pregnant women and their children. The joint efforts of AIDS Center, women’s consultation clinics, and maternity hospitals ensure the low rate of mother-tochild HIV transmission (1.3 % in 2007). The article reviews some advances as well as problems related to the medical treatment of HIV-positive pregnant women. The analysis of those issues will contribute to creation of a better healthcare system for pregnant women, will raise the awarness of how important medical monitroting and preventive care are and will favour further reduction of mother-to child transmission.Санкт-Петербург занимает лидирующие позиции в оказании помощи ВИЧ-инфицированным беременным женщинам и их детям. Совместные усилия специалистов Центра СПИД, женских консультаций, родовспомогательных учреждений обеспечивают низкую часто- ту перинатальной передачи ВИЧ (1,3% в 2017 г.). В статье отмечены успехи и некоторые проблемы в оказании помощи ВИЧ-инфицированным беременным женщинам, анализ которых будет способствовать улучшению организации помощи при беременности, повышению приверженности к наблюдению и профилактике, дальнейшему снижению числа детей с перинатальным путем заражения

    Epizootic Situation in the Crimean Federal District as Follows from Epidemiological Survey Results, 2014

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    The territory of the Crimean Peninsula is an endemic one as regards various natural-focal infections. The paper contains the data on epizootiological survey of 8 administrative regions of the Crimean Federal District (CFD). Carried out has been small mammals and Ixodidae ticks census. Identified is their species composition. Performed have been the field samples collection and laboratory studies for the presence of bacterial and viral infection agents. Established is the fact that H. marginatum is a dominating species among the ticks, collected during the spring season, while the house mouse prevails among the small mammals. As for the autumn collection of samples, the dominating species are H. punctata and common vole, respectively. Laboratory investigation results indicate the circulation of the agents of Ku fever, tick-borne spotty fever, Ixodidae tick-borne borreliosis, human granulocytic anaplasmosis, monocytic ehrlichiosis, hemorrhagic fever with renal syndrome and leptospirosis

    IL-12Rβ1 Deficiency in Two of Fifty Children with Severe Tuberculosis from Iran, Morocco, and Turkey

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    BACKGROUND AND OBJECTIVES: In the last decade, autosomal recessive IL-12Rβ1 deficiency has been diagnosed in four children with severe tuberculosis from three unrelated families from Morocco, Spain, and Turkey, providing proof-of-principle that tuberculosis in otherwise healthy children may result from single-gene inborn errors of immunity. We aimed to estimate the fraction of children developing severe tuberculosis due to IL-12Rβ1 deficiency in areas endemic for tuberculosis and where parental consanguinity is common. METHODS AND PRINCIPAL FINDINGS: We searched for IL12RB1 mutations in a series of 50 children from Iran, Morocco, and Turkey. All children had established severe pulmonary and/or disseminated tuberculosis requiring hospitalization and were otherwise normally resistant to weakly virulent BCG vaccines and environmental mycobacteria. In one child from Iran and another from Morocco, homozygosity for loss-of-function IL12RB1 alleles was documented, resulting in complete IL-12Rβ1 deficiency. Despite the small sample studied, our findings suggest that IL-12Rβ1 deficiency is not a very rare cause of pediatric tuberculosis in these countries, where it should be considered in selected children with severe disease. SIGNIFICANCE: This finding may have important medical implications, as recombinant IFN-γ is an effective treatment for mycobacterial infections in IL-12Rβ1-deficient patients. It also provides additional support for the view that severe tuberculosis in childhood may result from a collection of single-gene inborn errors of immunity
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