Obstructive sleep apnoea/hypopnoea syndrome: Relationship with obesity and management in obese patients

SUMMARY Obstructive sleep apnoea/hypopnoea syndrome (OSAHS) is a disease characterised by upper airway obstruction during sleep, quite frequent in the general population, even if underestimated. Snoring, sleep apnoea and diurnal hypersomnia are common in these patients. Central obesity plays a key role: it reduces the size and changes the conformation of the upper airways, besides preventing lung expansion, with consequent reduction of lung volumes. Furthermore, obese people are also resistant to leptin, which physiologically stimulates ventilation; as a result, this causes scarce awakening during apnoea. OSAHS diagnosis is based on the combination of clinical parameters, such as apnoea/hypopnoea index (AHI), medical history, physical examination and Mallampati score. The first objective reference method to identify OSAHS is polysomnography followed by sleep endoscopy. Therapy provides in the first instance reduction of body weight, followed by continuous positive airway pressure (CPAP), which still remains the treatment of choice in most patients, mandibular advancement devices (MAD) and finally otolaryngology or maxillofacial surgery. Among surgical techniques, central is barbed reposition pharyngoplasty (BRP), used in the field of multilevel surgery

Diversity of two short tandem repeat loci (CD4 and F13A1) in three Brazilian ethnic groups

Two microsatellites (CD4 and F13A1) were investigated in seven Brazilian populations: one group each of European- and African-derived subjects from Porto Alegre, southern Brazil, and five Amerindian tribes (three Tupi-Monde speaking [Gaviao, Surui, and Zoro], one Macro-Ge [Xavante], and one Carib [Wai-Wai]). For both markers, neo-Brazilians presented with a high diversity, but Amerindians showed a low level of variability. Genotype frequency distributions were heterogeneous among populations, the only exception being similar CD4 frequencies in Afro- and Euro-Brazilians. Gene diversity analysis revealed that most of the total variation is due to intrapopulational diversity in all populations, Because of the high information content of these markers in Afro- and Euro-Brazilians, these systems are most appropriate for forensic analyses. The comparison among Brazilian and other world populations revealed high similarity among populations of the same ethnic group, indicating a high discriminative power for these markers

H-BIM – Innovative and Digital Tools to Improve the Management of the Existing Buildings

With the introduction of the BIM methodology, the digitalization is consolidating mostly the process of new building design defining new standardized working procedures in order to optimize the data flow. On the contrary, pertaining to existing buildings, the rules are still dictated by the traditional methodology leading to fragmented and disaggregated information flow. However, some tools have been recently developed and are quickly upgrading to meet the specific aim to pursue progress, dynamism and experimentation in order to stay in tune with market demands. One common issue, is due to the fact that the documents are paper, hard to find and numerous so that the digitalization represents the best real solution to improve their management. In this regard, the heart of the informative flow is represented by the Common Data Environment (CDE), a cloud storage in which the documents are collected once uploaded and easily manageable with specific platforms. By way of example, a case study is developed in the paper in which the management process of the H-BIM of the XV century’s structure placed in the old town of Naples is carried out in a digital way, through the usBIM.platform (released by ACCA software company) using specific tools, like links, markers and tags. The goal of the paper is to define both a new organization for the data archive, in which the documents are structured and easily traceable, both a new way of conceiving the BIM model that it is thought as an informative vehicle and a key access to the information rather than a mere geometric representation

Identità e relazioni sociali. Dai popoli migranti alla cultura del Web 2.0

Nel saggio è una riflessione preliminare su cos'è da intendere per identità prima di individuare il ruolo che svolge la comunicazione non solo nel mantenere ma anche e soprattutto nel costruire identità e nel gestire relazioni, nel senso di crearle, mutarle o annullarle.The essay is a reflection about identity and role of communication on creating, mantaining and destroying social relations

Ship-to-ship LNG Bunkering: Risk Assessment and Safety Zones

In this paper risk assessment for the ship to ship LNG bunkering is carried out by exploiting the results of the projects “SUstainability PERformance of LNG-based maritime mobility – PLUS” (SUPER-LNG PLUS) financed by Interreg-Adrion and the project “Risk management system for design and operation of installations for LNG refuelling” (TRiTON) financed by the Greek government. Ship to ship bunkering constitutes a simple method when storage tanks cannot be installed in the port areas. In brief, risk assessment is conducted in the following basic steps: a) assessment of plant damage states and their frequency of occurrence, b) assessment of consequences and c) risk integration. First, the Master Logic Diagram (MLD) technique is used to identify the initial events that create a disturbance in the installation and have the potential to lead to an LNG release during a ship to ship bunkering operation. Moreover, safety functions and systems for preventing LNG release, are identified and Event trees are developed to model the accident sequences which lead to damage states. By exploiting available failure rate data, the frequency of each damage state is estimated. In parallel, the consequences of LNG release are estimated based on the heat radiation or overpressure dose an individual receives. Finally, iso-risk contours are calculated by combining the frequencies of the various accidents with the corresponding consequences. A case study for a ship to ship bunkering in a Greek port is presented

Performance assessment of drop tube reactor for biomass fast pyrolysis using process simulator

Biomass pyrolysis process from a drop tube reactor was modelled in a plug flow reactor using Aspen Plus process simulation software. A kinetic mechanism for pyrolysis was developed considering the recent improvements and updated kinetic schemes to account for different content of cellulose, hemicellulose, and lignin. In this regard, oak, beechwood, rice straw, and cassava stalk biomasses were analyzed. The main phenomena governing the pyrolysis process are identified in terms of the characteristic times. Pyrolysis process was found to be reaction rate controlled. Effects of pyrolysis temperature on bio-oil, gases, and char yields were evaluated. At optimum pyrolysis conditions (i.e., 500?), a bio-oil yield of 67.3, 64, 43, and 52 wt.% were obtained from oak, beechwood, rice straw, and cassava stalk, respectively. Oak and beechwood were found to give high yields of bio-oil, while rice straw produced high gas and char yields compared to other biomasses. Although temperature is the main factor that plays a key role in the distribution of pyrolysis products, the composition of cellulose, hemicellulose, and lignin in the feedstock also determines the yield behaviour and composition of products. With the rise in pyrolysis temperature, further decomposition of intermediate components was initiated favouring the formation of lighter fractions. Comparably, species belonging to the aldehyde chemical family had the highest share of bio-oil components in all the investigated feedstocks. Overall, the present study shows a good agreement with the experimental study reported in the literature, confirming its validity as a predictive tool for the biomass pyrolysis process