Intraabdominal infections

Intraabdominal infeksiyonlar (İAİ) akut apandisit gibi basit bir abdominal infeksiyondan ciddi sonuçları olan barsak infarktına kadar uzanan heterojen bir grup cerrahi alan infeksiyonunu tanımlar. İAİ’lar toplumdan kaynaklı veya sağlık bakımı ile ilişkili olabilir. İAİ olan hastalarda erken tanı, kaynak kontrolü ve uygun amprik tedavi ile morbidite ve mortalite önlenebilir. Bu yazıda erişkin ve çocuklarda gözlenen İAİ’ların tanı ve tedavi özellikleri güncel rehberler ışığında derlenmeye çalışılmıştır.Intraabdominal infections (IAI) defined a heteregous group of surgical site infections ranging from a simple abdominal infection such as acute appendicitis, to an intestinal infarct with severe consequences. IAI may be seen either community acquired or health-care related. Mortality and morbidity can be prevented by early diagnosis, source control and appropriate ampric treatment. It is aimed to review the diagnostic and treatment features of IAI in adults and children with the light of current guidelines

Pharmacokinetics and pharmacodynamics of aprepitant for the prevention of postoperative nausea and vomiting in pediatric subjects

Background/purpose: This multicenter, randomized, partially-blinded phase IIb study evaluated the pharmacokinetics (PK)/pharmacodynamics, safety, and tolerability of aprepitant in pediatric subjects for the prevention of postoperative nausea and vomiting (PONV)

Our approach to esophageal perforation secondary to dilatation of caustic esophageal stricture in children

Background: This study aims to review our 20-year experience in children with esophageal perforation and develop an algorithm