474 research outputs found

    Analisis Peran Keluarga Masdar Pasmar dalam Birokrasi Pemerintahan di Kabupaten Polewali Mandar

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    : This study attempts to analyze the role of the family masdar pasmar in bureaucracy government in district polewali mandar and how the role of a raid in legal-formal in bureaucracy go- vernment can run and maintain power. This research using the kind of research in eksploratory qualitative. Scope of research location was conducted in districts Polewali Mandar. The result showed the role of the family Masdar Pasmar in bureaucracy government can be seen and observed in aspects of power player, include visible and invisible power. The causes of strengthe- ning terjabarkan role in of economic capital, social capital and culturally capital . Strengthening the role of this family pattern government made bureaucratic local Polewali Mandar be bureaucracy with patrimonial pattern

    Strategi Pemasaran Kue Bagea sebagai Kue Khas Kota Palopo dengan Menggunakan Analisis Swot pada UKM Multi Kue Kota Palopo

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    Indonesia merupakan negara yang memiliki keanekaragaman jenis kuliner yang dapat dikembangkan menjadi sebuah unit bisnis. UKM Multi Kue merupakan salah satu unit USAha yang memproduksi kue bagea yang menjadi kue khas Kota Palopo. Tujuan penelitian ini untuk mengidentifikasi faktor yang paling berpengaruh terhadap volume penjualan pada UKM Multi Kue berdasarkan analisis dari marketing mix (atribut produk, harga, saluran distribusi, promosi, orang, proses, lingkungan fisik) untuk menentukan alternatif strategi pemasaran kue bagea berdasarkan analisis SWOT. Hasil penelitian menunjukkan bahwa pada persamaan regresi linier berganda, didapatkan variabel produk merupakan variabel yang paling berpengaruh terhadap volume penjualan pada UKM Multi Kue. Hasil analisis diagram SWOT pada Matriks IFE, diperoleh skor faktor kekuatan adalah 3,28 dan skor faktor kelemahan adalah 0,10 dengan selisih sebesar 3,18. Sementara itu, berdasarkan Matriks EFE, skor faktor peluang adalah 2,38 dan skor faktor ancaman adalah 0,74 dengan selisih sebesar 1,64. Selisih skor pada matriks IFE dan EFE menunjukkan bahwa UKM Multi Kue berada pada Kuadran I yang berarti bahwa strategi yang digunakan adalah strategi Strengths Opportunities (SO) atau strategi Growth yang menunjukkan bahwa UKM Multi Kue tergolong dalam USAha yang berkembang dan memiliki posisi yang kuat dan berpeluang

    Dualisme Kelembagaan antara Pemerintah Kota dan Badan Pengusahaan Batam Serta Dampaknya terhadap Kinerja Perekonomian di Kota Batam

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    The development of special areas of Batam began in the 1970s. With the support of special regulations made by the central government, Batam City becomes a competitive place for investment in Indonesia. Moreover Batam has geographical advantage because of its strategic location and adjacent to Malaysia and Singapore. However, problems arise when the central government begins to impose regional autonomy. The birth of Batam City caused an overlapping of authority between the Local Government of Batam and the Batam Authority which caused the management of Batam Island to be not harmonious. This study aims to identify the problem of institutional dualism that occurred between the Local Government of Batam and the Batam Authority and its impact on economic performance in Batam City. This research is explanatory, the data used are primary and secondary data. The results show the fact that the main problems in governance in Batam City is the occurrence of dualism authority between the Local Government of Batam and the Batam Authority. This is shown by the fact that the overlapping of authority between Local Government of Batam and the Batam Authority occurs in several sectors, especially in land management, overlapping licensing in Batam, airport and port management. This condition led to a decline in economic performance in Batam and the decline of Batam's economic competitiveness

    Influence of keratinized mucosa on the surgical therapeutical outcomes of peri-implantitis

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    AimTo assess the impact of keratinized mucosa (KM) width around dental implants on surgical therapeutic outcomes when treating peri- implantitis.Material and MethodsSurgically treated peri- implantitis implants were divided into two groups (KM width  .01). Between T1 and T2, no major differences were noted on PPD reduction, BOP and MBL changes between the two groups. GEE modelling demonstrated that MBL severity prior to surgical therapy was a better predictor for implant survival than KM width.ConclusionSurgical outcome in treating peri- implantitis was influenced by the severity of bone loss present at the time of treatment and not by the presence of KM at the time of treatment.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/154633/1/jcpe13250.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/154633/2/jcpe13250_am.pd

    Recommendations for successful virtual patient-assisted esthetic implant rehabilitation: A guide for optimal function and clinical efficiency

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    OBJECTIVE Complete arch implant rehabilitation necessitates meticulous treatment planning and high-level collaboration between surgical and prosthetic dental teams. Emerging virtual technologies hold considerable promise in streamlining this process. The aim of this article is to extend recommendations to clinicians venturing into the virtual patient-assisted esthetic implant rehabilitation workflow. OVERVIEW This article summarizes recommendations for virtual patient-assisted esthetic implant rehabilitation in the following five aspects: three-dimensional data handling and superimposition, occlusion and virtual articulator integration in creating virtual patients, streamlined face- and prosthetic-driven surgical planning, reuse of presurgical data ("Copy & Paste"), and final impression for passive fitting of final restoration. To illustrate these principles, a case with complete-mouth implant rehabilitation completed within six visits using this virtual patient workflow is presented. CONCLUSION The virtual patient workflow serves as an invaluable tool to perform treatment planning, enhance efficiency, and ensure predictable outcomes in esthetic complete arch implant rehabilitation. CLINICAL SIGNIFICANCE Virtual workflows are increasingly prevalent in esthetic implant rehabilitation. Nevertheless, these workflows necessitate a distinct set of knowledge and tools divergent from conventional dentistry practices. This article offers guidelines and recommendations for dental clinicians who are new to this field

    Using periodontal staging and grading system as a prognostic factor for future tooth loss: A long- term retrospective study

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    BackgroundA new classification of periodontal diseases aimed to identify periodontal disease based on a multidimensional staging and grading system has been recently proposed. However, up to date, its prognostic predictive capability has not been investigated. The aim of this study was to assess if parameters included in the new classification were predictive of tooth loss after a long- term follow- up (>10 years) in patients with periodontitis.MethodsPatients presented with periodontitis at the University of Michigan between January 1966 and January 2004 were screened and categorized according to the new classification of periodontitis. Number/Reasons of teeth loss in patients who underwent at least one session/year of maintenance during the entire follow- up period were extracted and used to analyze the prognostic capabilities of variables (staging, grading, and Extent) included in the new classification.ResultsA total number of 292 patients with a mean follow- up of 289.7 ± 79.6 months were included. 31 (10.6%) patients were classified as Stage 1, 85 (29.1%) as Stage 2, 146 (50%) as Stage 3, and 30 (10.3%) as Stage 4. For grading, 34 (11.7%) were classified as Grade A, 193 (66.1%) as Grade B, and 65 (22.2%) as Grade C. Results of multilevel Cox regression analyses revealed a statistically significant association between stage (HR:3.73 between Stage 4 and Stage 1) and grade (HR: 4.83 between Grade C and Grade A) at baseline and periodontal related tooth loss, whereas no differences were detected for the extent of periodontitis.ConclusionThis study provides the initial evidence regarding the predictive ability of the new classification of periodontitis. Patients in either Stage 4 or Grade C showed a significantly higher periodontal- related tooth loss.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/154975/1/jper10442_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/154975/2/jper10442.pd

    Overview of large area triple-GEM detectors for the CMS forward muon upgrade

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    In order to cope with the harsh environment expected from the high luminosity LHC, the CMS forward muon system requires an upgrade. The two main challenges expected in this environment are an increase in the trigger rate and increased background radiation leading to a potential degradation of the particle ID performance. Additionally, upgrades to other subdetectors of CMS allow for extended coverage for particle tracking, and adding muon system coverage to this region will further enhance the performance of CMS

    Cten Is Targeted by Kras Signalling to Regulate Cell Motility in the Colon and Pancreas

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    CTEN/TNS4 is an oncogene in colorectal cancer (CRC) which enhances cell motility although the mechanism of Cten regulation is unknown. We found an association between high Cten expression and KRAS/BRAF mutation in a series of CRC cell lines (p = 0.03) and hypothesised that Kras may regulate Cten. To test this, Kras was knocked-down (using small interfering (si)RNA) in CRC cell lines SW620 and DLD1 (high Cten expressors and mutant for KRAS). In each cell line, Kras knockdown was mirrored by down-regulation of Cten Since Kras signals through Braf, we tested the effect of Kras knockdown in CRC cell line Colo205 (which shows high Cten expression and is mutant for BRAF but wild type for KRAS). Cten levels were unaffected by Kras knockdown whilst Braf knockdown resulted in reduced Cten expression suggesting that Kras signals via Braf to regulate Cten. Quantification of Cten mRNA and protein analysis following proteasome inhibition suggested that regulation was of Cten transcription. Kras knockdown inhibited cell motility. To test whether this could be mediated through Cten, SW620 cells were co-transfected with Kras specific siRNAs and a Cten expression vector. Restoring Cten expression was able to restore cell motility despite Kras knockdown (transwell migration and wounding assay, p<0.001 for both). Since KRAS is mutated in many cancers, we investigated whether this relationship could be demonstrated in other tumour models. The experiments were repeated in the pancreatic cancer cell lines Colo357 & PSN-1(both high Cten expressors and mutant for KRAS). In both cell lines, Kras was shown to regulate Cten and forced expression of Cten was able to rescue loss of cell motility following Kras knockdown in PSN-1 (transwell migration assay, p<0.001). We conclude that, in the colon and pancreas, Cten is a downstream target of Kras and may be a mechanism through which Kras regulates of cell motility
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