137 research outputs found
The Supply Chain Role of Transaction Processing System in Customer Relationship Management
The aim of this study is to examine the supply chain role of the Transaction Processing System (TPS) on customer relationship management using empirical analysis. The study employed the opinions of 47 managers from selected banks in Baghdad that are known for the use of TPS through the collection and transaction store or from the decision-makers in the organizations. The result showed that there is a correlation between TPS and effective use of customer relationship management except when data are interned
Association of ADH1 and DDR48 Expression with Azole Resistance in Candida Albicans
Objectives: The ADH1 (alcohol dehydrogenase) and DDR48 genes were found to be upregulated in fluconazole resistant Candida albicans. Understanding the drug resistance mechanisms and genes will help in the development of new antifungal agents that can reverse drug resistance. This study aimed to investigate the role of ADH1and DDR48 genes in fluconazole resistance in C. albicans.Methods: This study involved 19 fluconazole susceptible and 6 fluconazole resistant C. albicans isolates. The MICs of fluconazole were determined by the E-test. Quantitative expressions of ADH1, CDR1 (Candida Drug Resistance), DDR48 and FLU1 genes were assessed by real time PCR.Results: There was a statistically significant higher expression levels of CDR1, FLU1, ADH1 and DDR48 in resistant and susceptible dose dependent isolates than in susceptible isolates (P = 0.009, 0.008, 0.01, 0.014 respectively). Strong positive correlations were observed between the expression levels of each of ADH1and DDR4 with azole resistance genes CDR1 and FLU1 [(rs) = 0.945, 0.815, respectively; P <0.001; (rs) = 0.852 and 0.76, respectively; P <0.001].Conclusions: This is the first study that showed positive correlation between DDR48 and azole resistance genes. It indicated that ADH1 and DDR48 are associated with the resistance mechanisms of C. albicans to fluconazole. Identification of new drugs that target the proteins encoded by these genes will help in eradication of fluconazole resistant C. albicans
A COMPARATIVE STUDY OF CHEMICAL COMPOSITION OF ACACIA SEYAL STEM, STEM WOOD AND STEM BARK DRY DISTILLATES USED BY SUDANESES WOMEN AS COSMETIC AND MEDICINE
Objective: The content and chemical composition of dry distillates of the stem, stem wood and stem bark of Acacia seyal were investigated. The distillates are fumigants of A. seyal locally known in Sudan as Dokhan and widely used for its cosmetic, aromatic and medicinal value for the treatment of candidiasis, genital yeast infection, urinary tract infection, diarrhoea, respiratory tract infection, skin infection and with potent, antioxidant and antimicrobial activities.Methods: The dry distillates were prepared by dry distillation method from the Acacia seyal stem, stem wood and stem bark and investigated chemically by GC-MS analysis.Results: The percentage yield of dry distillates (Dokhan) wer found to be 4.0 %, 4.8%, 1.4.1% v/w for stem, stem wood and stem bark respectively. GC-MS analysis revealed the presence of one hundred and twenty three constituents in the stem distillate with major constituents of solerone (7.27%), furfural (7.15%), catechol (7.11%), syringol (5.56%), allo-inositol (4.86%), mequinol (4.81%), furfuralcohol (3.35%), 3-methyl-1,2-cyclopentanedione (3.24%), phenol (2.73%), homovanillyl alcohol (2.56%) and 3-cresol (2.11%). the wood distillate show detection of eighty compounds, with main compounds: 1, 3-dimethyl-5-methoxypyrazol (10.61%), syringol (6.75%), furfuralcohol (5.24%), mequinol (4.49%), 1,2-anhydro-3,4,5,6-alloinositol (4.26%), 3-methyl-1,2-cyclopentanedione (3.42%), catechol (3.37%), 3-methoxycatechol (3.22%), homovanillyl alcohol (2.78%), homosyringic acid (2.40%), 3-cresol (2.18%), 3-methyl-2-cyclopentenone (2.44%) and 1,2-cyclopentanedione (2.03%). Sixty six compounds were detected in the distillate bark and the main compounds were found to be hexadecanoic (62.83%), catechol (3.38%), tetrapentacontane (3.18%), phenol (2.72%), mequinol (2.30%) and 2-ethylfurane (2.22%).Conclusion: The result concludes that the medicinal Sudanese Dokhan have good potential as sources of different bioactive compounds and antioxidants
Treatment-seeking behaviour for malaria in children under five years of age: implication for home management in rural areas with high seasonal transmission in Sudan
BACKGROUND: Effective management of malaria in children under the age of 5 requires mothers to seek, obtain, and use medication appropriately. This is linked to timely decision, accessibility, correct use of the drugs and follow-up. The aim of the study is to identify the basis on which fever was recognized and classified and exploring factors involved in selection of different treatment options. METHODS: Data was obtained by interviewing 96 mothers who had brought their febrile children to selected health facilities, conduction of 10 focus group discussions with mothers at village level as well as by observation. RESULTS: A high score of mothers' knowledge and recognition of fever/malaria was recorded. Mothers usually start care at home and, within an average of three days, they shift to health workers if there was no response. The main health-seeking behaviour is to consult the nearest health facility or health personnel together with using traditional medicine or herbs. There are also health workers who visit patients at home. The majority of mothers with febrile children reported taking drugs before visiting a health facility. The choice between the available options determined by the availability of health facilities, user fees, satisfaction with services, difficulty to reach the facilities and believe in traditional medicine. CONCLUSION: Mothers usually go through different treatment option before consulting health facilities ending with obvious delay in seeking care. As early effective treatment is the main theme of the control programme, implementation of malaria home management strategy is urgently needed to improve the ongoing practice
Vagus Nerve Acupucture-Like Transcutanious Electrical Nerve Stimulation on Immunity After Liver Resection
Objective: To find out the therapeutic impact of acupuncture like-transcutaneous electrical nerve stimulation of vagus nerve on immunity after liver resection. Methods This was a single-blind randomized controlled trial. A total of sixty individuals who had undergone liver resection at the National Liver Institute Hospital at Menofiea University were randomly divided into two groups: study group A (n=30) and control group B (n=30). The study group had vagus nerve stimulation with acupuncture like-TENS parameters include low-frequency (2–10Hz), pulse width (100–40
Investigating internet of things impact on e-Learning system: An overview
e-Learning systems have reached their peak with the revolution of smart technologies. In the past few years, the Internet of Things (IoT) has become one of the most advanced and popular technologies, affecting many different areas. Using IoT in an e-learning system is a fantastic technology that improves the e-learning system and makes it more inventive and cutting-edge. The key challenge addressed in this study is the acceptance of IoT usage in e-learning systems as well as how to improve it so that it can be utilized properly. This research concentrates on how IoT can benefit e-learning systems and how it might benefit users of e-learning systems. A comprehensive literature review was conducted to get acquainted with the important research related to IoT technology and e-learning systems through online research databases and reliable scientific journals. The first research finding is that e-learning systems need such modern techniques as IoT to enable interconnection, increase reliability, and enhance the enjoyment of the educational process. The second result is that research related to the development of new technologies like the IoT has a significant impact on enhancing the performance of new systems and bringing about positive change. This study highlights the value of IoT, particularly in e-learning systems. It aids in the development of new strategies that will improve the efficacy of e-learning systems and stimulate researchers to develop advanced technology
Improving the Antimicrobial Activity of Bagasse Packaging Paper using Organophosphorus Dimers
The
antimicrobial properties of
bagasse paper sheets coated with natural polymers (chitosan, different ratios
of (gelatin/glycerol) + chitosan, hemicellulose, hemicellulose + glycerol,
hemicellulose+chitosan) or synthetic organophosphorus dimer compounds were
evaluated in this work. Hemicelluloses showed moderate activity against Bacillus subtilis and Candida albicans, while chitosan showed weak
activity against B. subtilis. The condition that offered the highest inhibitory
activity of
bagasse paper was the one coated with 1,3-diaryl-2,2,2,4,4,4-hexachlorocyclodiphosph(V)azane
(where aryl is p-chloroaniline or p-anisidine). The developed bagasse papers
were evaluated against Gram-positive bacteria, Gram-negative bacteria, yeasts, and fungi. The highest inhibitory
activity was obtained at a concentration of 200 mg/mL for p-chloroaniline with
an inhibition zone that varied for different microbes from 6.9 mm to 26 mm. The
highest inhibitory activity was obtained at 300–250 mg/mL for p-anisidine
against most of the pathogenic microorganisms with an inhibition zone that
varied for different microbes from 8 mm to 14.75 mm. The observed antimicrobial and antifungal activity properties
for bagasse paper coated with
1,3-diaryl 2,2,2,4,4,4-hexachlorocyclodiphosph(V)azane could be attributed to the
presence of Cl, P atoms, and the lone pair of electrons on N atoms in the
structure of the dimers
The factors influenced by stakeholder identification in E-learning systems: A survey
Identifying the appropriate stakeholder is an integral part of the requirements engineering process and the primary factor influencing system success. The E-learning system is a significant platform with a variety of stakeholders that must be identified. After the launch of the E-learning system, issues such as identifying stakeholders arise and threaten the system's continuity. Moreover, the use of non-scientific and incompatible methods for identifying stakeholders, as well as the limitations of some of these methods, are among other issues that are highlighted in this research. This study investigates the issue of Stakeholder Identification (SI) in the E-learning system and identifies the most influential factors influencing this significant issue. By conducting a comprehensive literature review and employing qualitative data collection and analysis, these factors are addressed. There were 35 survey questionnaires were distributed to experts, analysts, and developers in the field of the E-learning system in Malaysia in 2022 to collect the data. The results reported in this paper demonstrated that there are difficulties in defining the actual stakeholders, as well as a lack of knowledge in employing the appropriate techniques to identify them, which were then analysed and compared to generate the list of factors. The factors identified in this paper help industries understand how critical it is to identify the actual stakeholders of an E-learning system at an early stage. Therefore, industries should be able to develop stable and reliable E-learning systems. This research provides several contributions, including crucial theoretical and practical insights into how E-learning systems are used and adopted. Contributes to the current literature by outlining the key obstacles caused by SI concerns. Identify the most significant components of SI issues, i.e., information quality, time and cost, system utility, and technology. Finally, this paper provides important recommendations for academics, developers, and regulators, allowing them to better understand the critical factors of effective E-learning system implementation
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