GROWTH MINDSET IN ENGLISH LANGUAGE LEARNING OF COLLEGE STUDENTS

This study investigated the growth mindset of college students in English language learning and the challenges they encounter in an online setting. Using a researcher-made questionnaire about the growth mindset of college students in English language learning and the challenges they encounter in an online setting, data from the 60 respondents in the study coming from the different colleges or departments of the Notre Dame of Midsayap College were analyzed quantitatively. Findings indicated that students have a high growth mindset and that factors such as motivation, criticism, environment, and effort had played a major role in their English language learning. Major challenges of students in an online setting include finding difficulty in accessing online materials due to poor internet connection, experiencing headaches and body pains due to prolonged exposure to gadgets, and getting bored easily when class time is too lengthy. The least challenges encountered by students in an online setting yet also hampered their learning are lacking gadgets such as a cellphone and laptops, feeling disconnected from the instructor, and excessive workloads. Furthermore, there is no significant difference in a growth mindset in terms of sex and college or department. However, it was found out that College of Nursing (CN) got the highest mean when it comes to their growth mindset. Meanwhile, College of Information Technology, and Engineering (CITE) got the lowest mean. Moreover, there is a significant relationship between the growth mindset of English language learning and the challenges they encountered in an online setting.  Article visualizations

FoodComEx, a new chemical library for rare food-derived compounds

The lack of commercial standards for food-derived metabolites is a major limitation in nutritional metabolomics. FoodComEx (Food Compound Exchange) is a new chemical library initiated in the FoodBAll (Food Biomarkers Alliance) project (http://foodmetabolome.org) to facilitate the sharing of not easily accessible standards for food compounds and their human metabolites. FoodComEX (http://foodcomex.org/) will be a virtual library, with compounds stored in the laboratory where they have been isolated or synthesized. Version 1.0 will be an online catalog of pure compounds and reference materials (food extracts, biofluids from animals fed pure compounds, incubation media from in vitro systems to produce metabolites, etc.) made available by FoodBAll partners and associated collaborators. Each compound will appear with its elemental formula, monoisotopic mass, solubility, origin, purity, available quantity, storage conditions, stability, links to existing databases, type of spectral data available and contact details of the laboratory offering to share the standard. In the final version, which should be available at the end of 2016, spectral data (GC-MS, LC-MS, NMR, UV, IR) will be made searchable online. Anyone interested in one compound will directly contact the provider. A bilateral negotiation will define the terms of collaboration, within the rules defined in a charter of good practices. For example, the acquirer will have to share the spectral analyses acquired on his own analytical platform. This will continuously enrich the content of the chemical library. FoodComEx is a collaborative initiative widely open to new contributors and users. Anyone interested to contribute can contact u

Sofosbuvir-Based Direct-Acting Antiviral Therapies for Hcv in People Receiving Opioid Substitution Therapy: An Analysis of Phase 3 Studies

Background: Hepatitis C virus (HCV) direct-acting antiviral therapy is effective among people receiving opioid substitution therapy (OST), but studies are limited by small numbers of nongenotype 1 (GT1) patients. The aim of this study was to evaluate the treatment completion, adherence, SVR12, and safety of sofosbuvir-based therapies in HCV patients receiving and not receiving OST. Methods: Ten phase 3 studies of sofosbuvir-based regimens included ION (ledipasvir/sofosbuvir ± ribavirin for 8, 12, or 24 weeks in GT1), ASTRAL (sofosbuvir/velpatasvir for 12 weeks in GT1-6), and POLARIS (sofosbuvir/velpatasvir and sofosbuvir/velpatasvir/voxilaprevir in GT1-6). Patients with clinically significant drug use (last 12 months) or noncannabinoids detected at screening were ineligible. Results: Among 4743 patients, 4% (n = 194) were receiving OST (methadone; n = 113; buprenorphine, n = 75; other, n = 6). Compared with those not receiving OST (n = 4549), those receiving OST (n = 194) were younger (mean age, 48 vs 54), more often male (73% vs 61%), GT3 (38% vs 17%), treatment-naïve (78% vs 65%), and cirrhotic (36% vs 23%). Among those receiving and not receiving OST, there was no significant difference in treatment completion (97% vs 99%, P = .06), SVR12 (94% vs 97%, P = .06), relapse (0.5% vs 2.1%, P = .19), adverse events (78% vs 77%, P = .79), or serious adverse events (3.6% vs 2.4%, P = .24). There was no difference in SVR12 in patients with cirrhosis (99% vs 95%, P = .25) or those with G3 (95% vs 95%, P = .77) in those receiving OST. Among patients receiving OST, SVR12 was high among those receiving methadone (95%) and buprenorphine (96%). Conclusion: Sofosbuvir-based therapies are effective and safe in patients receiving OST.This work was supported by Gilead Sciences

Gavagai? The International Politics of Translation

This chapter unpacks the politics of translation in four steps. In a first step, it reviews how translation is made unproblematic in contexts as diverse as the literature on international norms, actor-network theory, and in a generalised attitude toward social research commonly dubbed ‘positivism’. Second, it turns to W. V. O. Quine’s influential take on the indeterminacy of translation to highlight how it effectively disrupts routinised attempts to render translation unproblematic. A third step discusses these attempts in the broader horizon of a quest for certainty, a longing for knowledge to stand on a firm ground, which contrasts sharply with the reflexive interplay of social relations of translation. In a concluding step, the chapter discusses the politics of both translation and untranslatability in terms of its inextricably international dimension