Right Ventricular Thrombus with Behçet's Syndrome: Successful Treatment with Warfarin and Immunosuppressive Agents

Behçet's syndrome is a chronic multisystem disease that presents with recurrent oral and genital ulceration and recurrent uveitis. Cardiac involvement is an extremely rare manifestation of this disorder

Prediction of subclinical left ventricular dysfunction with strain rate imaging in patients with mild to moderate rheumatic mitral stenosis

Background: Left ventricular (LV) long-axis function evaluated by Doppler tissue echocardiography-derived strain rate (SR) imaging has been shown to be a useful index of LV systolic function; however, it has not been evaluated in patients with mitral stenosis (MS). We examined the LV long-axis function of patients with pure MS and normal global systolic function as assessed by LV ejection fraction

Left Main Coronary Artery Thrombus Resulting from Combined Protein C and S Deficiency

Inherited hypercoagulopathies such as protein C and S deficiency usually lead to the formation of venous thrombi in clinical practice; however, they rarely lead to arterial thrombosis. It has been demonstrated that both protein C and S deficiency may lead to myocardial infarctions. However, our literature review revealed no reports of left main coronary artery thrombi caused by protein C and S deficiency. This paper presents a case of a left main coronary artery thrombus resulting from protein C and S deficiency in a young patient with normal coronary arteries

Effects of Impaired Fasting Glucose on Aortic Elasticity

Background: The pathophysiology of atherosclerosis development in patients with diabetes mellitus (DM) is similar to that in nondiabetics. However, atherosclerosis develops earlier and runs a rapid course in patients with diabetes. Aortic stiffness, strain and distensibility are the parameters used to assess an increase in arterial stiffness and can be measured by invasive and non-invasive methods

Investigation of the atrial electromechanical delay duration in Behcet patients by tissue Doppler echocardiography

Aims To investigate the atrial electromechanical delay (EMD) duration that is a non-invasive predictor of atrial fibrillation (AF) in patients with Behcet's disease (BD)

Evaluation of atrial electromechanical delay and left atrial mechanical function in patients with obstructive sleep apnea Cardiac involvement in patients with OSA

The aim of this study was to evaluate atrial electromechanical delay measured by tissue Doppler imaging and left atrial mechanical function in patients with obstructive sleep apnea (OSA)

Assessment of left atrial mechanical functions in thyroid dysfunction

INTRODUCTION Thyroid hormone deficiency can lead to the impairment of cardiac function

Wydłużona dyspersja załamka P u chorych ze stanem przedcukrzycowym

Background: It is known that overt diabetes as well as chronic hyperglycaemia can lead to atrial fibrillation. A P wave dispersion (PWD) represents heterogeneity in atrial refractoriness. Aim: To investigate PWDs in patients with pre-diabetes. Method: Based on the results of examinations, 84 pre-diabetic patients (the pre-DM group; 50 female, 34 male; mean age 54 &#177; 8.6 years) who had no overt diabetes, coronary artery disease or hypertension, whose fasting blood glucose was higher than 100 mg/dL and/or whose 2 h glucose concentrations on an oral glucose tolerance test was in the range of 140 to 199 mg/dL, and 48 healthy volunteers (the non-DM group, 30 female, 18 male; mean age 51.7 &#177; 7.3 years) with no illnesses, were enrolled in this study. Standard 12-lead electrocardiograms of all patients were taken at 50 mm/s and 20 mm/mV standardisation. Maximum (Pmax) and minimum (Pmin) P-wave durations were measured. The PWD was defined as the difference between Pmax and Pmin. Results: The Pmax and PWD values were significantly higher in pre-DM compared to non-DM (104 &#177; 13 ms vs 98 &#177; 12 ms; p < 0.05, 42 &#177; 13 ms vs 34 &#177; 11 ms; p < 0.01 respectively). A positive correlation was found between PWD and fasting blood glucose (r = 0.32; p 0.05). Multivariate regression analysis showed no relationship between PWD and age, left atrial diameter, E, A, E/A or HbA1c. However, there was a relationship between PWD and fasting blood glucose. Conclusions: The Pmax and PWD are increased in pre-diabetic patients who have no coronary artery disease, hypertension or left ventricular hypertrophy. Kardiol Pol 2011; 69, 6: 566&#8211;571Wstęp: Wiadomo, że jawna cukrzyca i jawna hiperglikemia mogą sprzyjać wystąpieniu migotania przedsionków. Cel: Celem pracy była zbadanie dyspersji załamka P (PWD) jako metody oceny heterogenności opornosci przedsionków u chorych ze stanem przedcukrzycowym. Metody: Na podstawie poniższych wyników do badania włączono 84 chorych ze stanem przedcukrzycowym (grupa pre- DM: 50 kobiet, 34 mężczyzn; średni wiek 54 &#177; 8,6 roku) bez jawnej cukrzycy, choroby wieńcowej czy nadciśnienia, u których stężenie glukozy na czczo wynosiło ponad 100 mg/dl i/lub u których stężenia glukozy po 2 h podczas testu doustnego obciążenia glukozą znajdowały się w zakresie 140&#8211;199 mg/dl, oraz 48 zdrowych ochotników (grupa non-DM: 30 kobiet, 18 mężczyzn, średni wiek 51,7 &#177; 7,3 roku) bez rozpoznanych chorób. Standardowy 12-odprowadzeniowy elektrokardiogram wykonano u wszystkich badanych przy standardowym przesuwie taśmy 50 mm/s z cechą 20 mm/mV. Zmierzono maksymalne (Pmax) i minimalne (Pmin) czasy trwania załamków P, a PWD zdefiniowano jako różnicę między Pmax i Pmin. Wyniki: Wartości Pmax oraz PWD były istotnie wyższe w grupie pre-DM w porównaniu z non-DM (odpowiednio 104 &#177; 13 ms v. 98 &#177; 12 ms; p < 0,05; 42 &#177; 13 ms v. 34 &#177; 11 ms; p < 0,01). Stwierdzono dodatnią korelację między PWD i stężeniem glukozy na czczo (r = 0,32; p 0,05). Wieloczynnikowa analiza regresji nie wykazała związku między PWD a wiekiem, wymiarem lewego przedsionka, wartościami E, A, E/A oraz HbA1c. Stwierdzono jednak zależność między PWD i stężeniem glukozy na czczo. Wnioski: Wartości Pmax oraz PWD mogą być zwiększone u osób ze stanem przedcukrzycowym bez rozpoznanej choroby wieńcowej, nadciśnienia czy przerostu lewej komory. Kardiol Pol 2011; 69, 6: 566&#8211;57