Effect of Notches on the Axial Fatigue Properties of Structural Steels

The effect of the stress concentration on the zero-to-tension axial fatigue strength of notched members of four structural steels has been studied. For each of the four steels a critical notch severity was found at which a transition in behavior takes place. When the theoretical stress concentration exceeds this critical value the fatigue strength increases instead of continuing to decrease as would normally be expected. The maximum effective stress concentration determined from these tests corresponds to a critical notch severity which is dependent on the material) the geometry of the specimen) and the cyclic conditions of stress. Microscopic examinations of the roots of the notched specimens which did not fail revealed cracking in most cases. Some of the cracks apparently were nonpropagating cracks but the test lives in most cases were insufficient to isolate such cracks positively as non-propagating. A study of other data on non-propagating cracks revealed that the laws governing their formation are not yet fully understood. However, there are indications that the increase in fatigue strength obtained above the critical notch severity is coincident with the formation of non~propagating cracks.The Engineering FoundationAmerican Iron and Steel InstituteChicago Bridge and Iron FoundationThe Welding Research Counci

Gender Discrimination: Beliefs and Experiences: A Comparative Perspective of Women and Men in the Delhi Police

Gender roles are learnt through the socialization process and subsequently extend to the work context where women and men are believed to have different characteristics and are therefore treated differently. The pervasiveness of workplace gender differences influence hiring practices, salaries and career growth opportunities for women. Gender-based work behavior differences are perceived to be much greater in male dominated professions like the police. While research suggests that there is no evidence that policewomen perform differently from their male counterparts in their day-to-day activities of police, negative male attitudes towards women in police significantly obstruct the advancement of policewomen. Induction of women in the police service in India is a recent change. This paper analyses the beliefs and unique experiences of women in a police department in Delhi, India. Using a comparative perspective, it examines the issues and challenges relating to women in police and the concomitant experiences of policemen, posed by the more recent entry of women in the service. Quantitative data, supported by in-depth interviews are obtained from a large sample of women and men from the rank and file of the police. The data suggest that gender based work behaviour differences are perceived to be predominant. Women are assigned peripheral roles and are yet to be integrated with the mainstream. These findings have significant implications for developing relevant human resource policies in police departments to deal with the changing demographics and for building a gender-inclusive organisation

Scrutinizing public expenditures: assessing the performance of public accounts committees

In 2002, David McGee wrote a comprehensive report on two important elements in the system of public financial accountability, namely the office of the Auditor General and the parliamentary oversight committee commonly referred to as the Public Accounts Committee (PAC). The purpose of the present paper is to deepen McGee's analysis of PACs. In particular, the authors define PAC success and identify those factors that affect PAC peformance. They use data that were collected by the World Bank Institute in 2002, when a survey questionnaire was sent to 51 national and state/provincial parliaments in Commonwealth countries in Asia and Australasia, and Canada and the United Kingdom. The authors find that the institutional factors which most account for the success of the PACs are the focus on government's financial activity rather than its policies, the power to investigate all past and present government expenses, the power to follow up on government action in response to its recommendations, and its relationship with the Auditors General.National Governance,Parliamentary Government,Politics and Government,Business Environment,Business in Development

Procarbazine, CCNU and vincristine (PCV) versus temozolomide chemotherapy for patients with low-grade glioma: a systematic review.

Low-grade gliomas (LGG) encompass a heterogeneous group of tumors that are clinically, histologically and molecularly diverse. Treatment decisions for patients with LGG are directed toward improving upon the natural history while limiting treatment-associated toxiceffects. Recent evidence has documented a utility for adjuvant chemotherapy with procarbazine, CCNU (lomustine), and vincristine (PCV) or temozolomide (TMZ). We sought to determine the comparative utility of PCV and TMZ for patients with LGG, particularly in context of molecular subtype. A literature search of PubMed was conducted to identify studies reporting patient response to PCV, TMZ, or a combination of chemotherapy and radiation therapy (RT). Eligibility criteria included patients 16 years of age and older, notation of LGG subtype, and report of progression-free survival (PFS), overall survival (OS), and treatment course. Level I, II, and III data were included. Adjuvant therapy with PCV resulted in prolonged PFS and OS in patients with newly diagnosed high-risk LGG. This benefit was accrued most significantly by patients with tumors harboring 1p/19q codeletion and IDH1 mutation. Adjuvant therapy with temozolomide was associated with lower toxicity than therapy with PCV. In patients with LGG with an unfavorable natural history, such as with intact 1p/19q and wild-type IDH1, RT/TMZ plus adjuvant TMZ may be the best option. Patients with biologically favorable high-risk LGG are likely to derive the most benefit from RT and adjuvant PCV

Comparative Analysis of Lycorine in Wild Plant and Callus Culture Samples of Hymenocallis littoralis by HPLC-UV Method

The Hymenocallis littoralis, an ornamental and medicinal plant, had been traditionally used for wound healing. In the present study, an analytical method using HPLC with ultraviolet detection was developed for the quantification of lycorine in the extracts of different parts of wild plant and tissue culture samples of H. littoralis.The separationwas achieved using a reversed-phase column. The method was found to be accurate, repeatable, and sensitive for the quantification of minute amount of lycorine present in the samples. The highest lycorine content was found in the bulb extract (2.54 ± 0.0

Symptomatic spinal metastasis: A systematic literature review of the preoperative prognostic factors for survival, neurological, functional and quality of life in surgically treated patients and methodological recommendations for prognostic studies

PURPOSE: While several clinical prediction rules (CPRs) of survival exist for patients with symptomatic spinal metastasis (SSM), these have variable prognostic ability and there is no recognized CPR for health related quality of life (HRQoL). We undertook a critical appraisal of the literature to identify key preoperative prognostic factors of clinical outcomes in patients with SSM who were treated surgically. The results of this study could be used to modify existing or develop new CPRs. METHODS: Seven electronic databases were searched (1990-2015), without language restriction, to identify studies that performed multivariate analysis of preoperative predictors of survival, neurological, functional and HRQoL outcomes in surgical patients with SSM. Individual studies were assessed for class of evidence. The strength of the overall body of evidence was evaluated using GRADE for each predictor. RESULTS: Among 4,818 unique citations, 17 were included; all were in English, rated Class III and focused on survival, revealing a total of 46 predictors. The strength of the overall body of evidence was very low for 39 and low for 7 predictors. Due to considerable heterogeneity in patient samples and prognostic factors investigated as well as several methodological issues, our results had a moderately high risk of bias and were difficult to interpret. CONCLUSIONS: The quality of evidence for predictors of survival was, at best, low. We failed to identify studies that evaluated preoperative prognostic factors for neurological, functional, or HRQoL outcomes in surgical patients with SSM. We formulated methodological recommendations for prognostic studies to promote acquiring high-quality evidence to better estimate predictor effect sizes to improve patient education, surgical decision-making and development of CPRs

An update on radiation therapy for brain metastases

published_or_final_versio

Market discipline and Basel Pillar 3 reporting

In this paper we examine the role of Basel Pillar 3 risk reporting in improving market transparency. Pillar 3 reporting requirements vary widely across countries; most banks in Europe release Pillar 3 risk reports annually after their annual reports are published and information contained in these reports does not elicit a stock market reaction. Australian banks, on the other hand, release Pillar 3 reports quarterly, independent of their annual reports. We find that this higher frequency of information disclosure is useful to investors and they react positively to reports of an increase in capital and negatively to a decrease in credit quality. We also find that investors ignore changes in the risk-weighted assets of a bank, but pay attention to total credit exposure. This study informs regulators and market participants on the efficacy of Pillar 3 risk reporting with several policy implications

[v]at is going on? Local and global ideologies about Indian English

ABSTRACTThis article examines local and global language ideologies surrounding a particular phonetic feature in Indian English, the pronunciation of /v/ as [w]. By focusing on how local and global participants – both individuals and institutions – imagine language variation through disparate framings of “neutral” and “standard,” it highlights how processes of globalization and localization are interconnected, dialogic, and symbiotic. Compared are (i) sociolinguistic constructions of Indian cartoon characters, (ii) American “accent training” institutes, (iii) Indian call center and language improvement books, (iv) American speakers’ interpretations of merged IE speech, and, (v) IE speakers’ attitudes about IE, “neutral,” and ”standard” language. The relative social capital of these populations mediates both how each constructs its respective ideology about language variation, and how these ideologies dialogically interact with each other. (Language variation, language ideologies, dialogic, standard language)1</jats:p