1,602 research outputs found

    Transport properties of single channel quantum wires with an impurity: Influence of finite length and temperature on average current and noise

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    The inhomogeneous Tomonaga Luttinger liquid model describing an interacting quantum wire adiabatically coupled to non-interacting leads is analyzed in the presence of a weak impurity within the wire. Due to strong electronic correlations in the wire, the effects of impurity backscattering, finite bias, finite temperature, and finite length lead to characteristic non-monotonic parameter dependencies of the average current. We discuss oscillations of the non-linear current voltage characteristics that arise due to reflections of plasmon modes at the impurity and quasi Andreev reflections at the contacts, and show how these oscillations are washed out by decoherence at finite temperature. Furthermore, the finite frequency current noise is investigated in detail. We find that the effective charge extracted in the shot noise regime in the weak backscattering limit decisively depends on the noise frequency ω\omega relative to vF/gLv_F/gL, where vFv_F is the Fermi velocity, gg the Tomonaga Luttinger interaction parameter, and LL the length of the wire. The interplay of finite bias, finite temperature, and finite length yields rich structure in the noise spectrum which crucially depends on the electron-electron interaction. In particular, the excess noise, defined as the change of the noise due to the applied voltage, can become negative and is non-vanishing even for noise frequencies larger than the applied voltage, which are signatures of correlation effects.Comment: 28 pages, 19 figures, published version with minor change

    Thirty Femtograms Detection of Iron in Mammalian Cells

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    Inorganic nanomaterials and particles with enhanced optical, mechanical or magnetic attributes are currently being developed for a wide range of applications. Safety issues have been formulated however concerning their potential cyto- and genotoxicity. For in vivo and in vitro experimentations, recent developments have heightened the need of simple and facile methods to measure the amount of nanoparticles taken up by cells or tissues. In this work, we present a rapid and highly sensitive method for quantifying the uptake of iron oxide nanoparticles in mammalian cells. Our approach exploits the digestion of incubated cells with concentrated hydrochloric acid reactant and a colorimetric based UV-Visible absorption technique. The technique allows the detection of iron in cells over 4 decades in masses, from 0.03 to 300 picograms per cell. Applied on particles of different surface chemistry and sizes, the protocol demonstrates that the coating is the key parameter in the nanoparticle/cell interactions. The data are corroborated by scanning and transmission electron microscopy and stress the importance of resiliently adsorbed nanoparticles at the plasma membrane.Comment: 18 pages, 6 figure

    An Evaluation of Physical Activity Levels amongst University Employees

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    Approximately 60% of the world’s population do not meet the physical activity (PA) guidelines. Physical inactivity is increasing in occupations, with work-related health issues becoming more prevalent. University employees’ work in a range of job roles and PA levels in this population is unclear. Thus, this study aimed to evaluate PA levels amongst university employees in a UK Higher Education institution. Four hundred employees (male = 131, female = 269) partook in this quantitative study and completed an online International Physical Activity Questionnaire Long Form (IPAQ-LF) to assess total moderate to vigorous PA (MVPA) and work-related MVPA. A Mann-Whitney U test examined differences in total MVPA and work-related MVPA between genders and a Kruskal-Wallis H test examined differences in total MVPA and work related MVPA between job roles. The findings showed that university employees engaged in a median of 330 minutes and 1770 METs of MVPA across all domains of IPAQ-LF. Further, the median time spent in total work PA was 30 minutes and 123 METs. There was a significant difference between genders, as males engaged in 150 minutes more total MVPA compared to females (p 0.05). Findings suggest that job role does not affect PA levels within university workplace, although they do propose that males engage in more MVPA compared to females. As a result of the subjective nature of this research, objective research is required to confirm current findings

    Intrusion detection with Parameterized Methods for Wireless Sensor Networks

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    Current network intrusion detection systems lack adaptability to the frequently changing network environments. Furthermore, intrusion detection in the new distributed architectures is now a major requirement. In this paper, we propose two Adaboost based intrusion detection algorithms. In the first algorithm, a traditional online Adaboost process is used where decision stumps are used as weak classifiers. In the second algorithm, an improved online Adaboost process is proposed, and online Gaussian mixture models (GMMs) are used as weak classifiers. We further propose a distributed intrusion detection framework, in which a local parameterized detection model is constructed in each node using the online Adaboost algorithm. A global detection model is constructed in each node by combining the local parametric models using a small number of samples in the node. This combination is achieved using an algorithm based on particle swarm optimization (PSO) and support vector machines. The global model in each node is used to detect intrusions. Experimental results show that the improved online Adaboost process with GMMs obtains a higher detection rate and a lower false alarm rate than the traditional online Adaboost process that uses decision stumps. Both the algorithms outperform existing intrusion detection algorithms. It is also shown that our PSO, and SVM-based algorithm effectively combines the local detection models into the global model in each node; the global model in a node can handle the intrusion types that are found in other nodes, without sharing the samples of these intrusion types

    In vitro toxicity of nanoceria: effect of coating and stability in biofluids

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    Due to the increasing use of nanometric cerium oxide in applications, concerns about the toxicity of these particles have been raised and have resulted in a large number of investigations. We report here on the interactions between 7 nm anionically charged cerium oxide particles and living mammalian cells. By a modification of the particle coating including low-molecular weight ligands and polymers, two generic behaviors are compared: particles coated with citrate ions that precipitate in biofluids and particles coated with poly(acrylic acid) that are stable and remain nanometric. We find that nanoceria covered with both coating agents are taken up by mouse fibroblasts and localized into membrane-bound compartments. However, flow cytometry and electron microscopy reveal that as a result of their precipitation, citrate-coated particles interact more strongly with cells. At cerium concentration above 1 mM, only citrate-coated nanoceria (and not particles coated with poly(acrylic acid)) display toxicity and moderate genotoxicity. The results demonstrate that the control of the surface chemistry of the particles and its ability to prevent aggregation can affect the toxicity of nanomaterials.Comment: 33 pages 10 figures, accepted at Nanotoxicolog

    In vitro toxicity and uptake of magnetic nanorods

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    In this paper we investigate the internalization and cytotoxicity of nanostructured materials having the form of elongated rods, with diameter of 200 nm and lengths 1 - 10 {\mu}m. The rods were made from the controlled aggregation of sub-10 nm iron oxide nanoparticles. Recently, we have shown that the nanorods inherited the superparamagnetic property of the particles. These rods can actually be moved by the application of an external magnetic field. Here we evaluate the in vitro toxicity of the magnetic nanorods by using MTT assays on NIH/3T3 mouse fibroblasts. The toxicity assays revealed that the nanorods are biocompatible, as exposed cells remained 100% viable relative to controls over a period of a few days. Optical microscopy allow to visualize the rods inside the cells and to determine their number per cell. Roughly 1/3 of the total incubated rods were uptaken by the fibroblasts.Comment: 8 pages, 5 figure

    External voltage sources and Tunneling in quantum wires

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    We (re) consider in this paper the problem of tunneling through an impurity in a quantum wire with arbitrary Luttinger interaction parameter. By combining the integrable approach developed in the case of Quantum Hall edge states with the introduction of radiative boundary conditions to describe the adiabatic coupling to reservoirs, we are able to obtain the exact equilibrium and non equilibrium current. One of the most striking features observed is the appearance of negative differential conductances out of equilibrium in the strongly interacting regime g <=.2. In spite of the various charging effects, a remarkable form of duality is still observed. New results on the computation of transport properties in integrable impurity problems are gathered in appendices. In particular, we prove that the TBA results satisfy a remarkable relation, originally derived using the Keldysh formalism, between the order T^2 correction to the current out of equilibrium and the second derivative of this current at T=0 with respect to the voltage.Comment: 16 pages, 7 figure

    A Comparison of Physical Activity and Sedentary Lifestyle of University Employees through ActiGraph and IPAQ-LF

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    Introduction: The benefits of participating in physical activity (PA) are wide-ranging, such as lowering the risk of diabetes and anxiety. Employees’ engagement in PA can also benefit their employers due to the potential reduction in absenteeism and increased productivity. However, the PA levels and sedentary behaviour of university employees are yet to be examined using a mixed methods approach. This study aimed to monitor the PA and sedentary lifestyle (SL) of university employees’ objectively and subjectively for a whole week. Methods: Sixty-four employees (male = 33; female = 31) wore a PA monitor for a whole week and simultaneously completed the International Physical Activity Questionnaire Long Form (IPAQ-LF) to evaluate light, moderate to vigorous physical activity (MVPA), and SL amongst employees from different job roles such as Academics, Administration, and Professionals Service. Results: The ActiGraph results determined that employees engaged in significantly more light PA, and MVPA compared to the self-reported IPAQ-LF (p 0.05). However, there were significant differences across gender light PA Z = –6.139, p = .001, MVPA Z = –4.962, p = .001 but no significant differences in SL Z = –.869, p = .385. Also, there were significant differences across job roles light PA, MVPA (p 0.05). Discussion and conclusion: Findings suggest, IPAQ-LF presented lower light PA, MVPA, and SL than ActiGraph. Thus, considering the impact of prolonged SL on health and wellbeing, future research is needed to explore the challenges this population faces regarding PA engagement and propose potential interventions to reduce SL amongst university employees

    Matching Morphology and Diet in the Disc-Winged Bat Thyroptera tricolor (Chiroptera)

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    The dietary niche and morphological adaptations of a species should be highly correlated. However, conflicting selective pressures may make predictions about diet difficult without additional knowledge of a species' life history. We tested the reliability of predicting a bat's diet from its wing morphology using data for Spix's disk-winged bat (Thyroptera tricolor). The species had been predicted to fall within either the aerial hawking or gleaning foraging group. We compared the results of a theoretical (canonical discriminant function analysis of morphology) and an applied (analysis of droppings) method of diet determination. Our results place T. tricolor in the gleaning functional group with a 77% probability according to morphology. Correspondingly, a large proportion of the diverse diet consisted of nonflying prey, such as spiders, insect larvae, and other silent prey, which should be difficult to detect using echolocation. Although some flying prey were taken, it is clear that T. tricolor regularly gleans prey from surfaces, indicating that for this species, morphology is a useful indicator of diet. However, the breadth of the diet; the high proportion of jumping spiders, leafhoppers, and insect larvae; and the extremely small size of prey were unique features of the diet that could not be predicted from morphology alone. Thus, although comparative statistical methods and the analysis of wing morphology may be helpful to predict the general ecological niche, only detailed investigation of the life history may yield the detail needed for understanding the link between morphology and ecology of individual specie

    Luttinger liquid superlattices

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    We calculate the correlation functions and the DC conductivity of Luttinger liquid superlattices, modeled by a repeated pattern of interacting and free Luttinger liquids. In a specific realization, where the interacting subsystem is a Hubbard chain, the system exhibits a rich phase diagram with four different phases: two metals and two compressible insulators. In general, we find that the effective low energy description amalgamates features of both types of liquids in proportion to their spatial extent, suggesting the interesting possibility of `engineered' Luttinger liquids.Comment: RevTeX, 5 pages, 3 figure
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