563 research outputs found
Comment on `Strong Vortex Liquid Correlation' from Multiterminal Measurements on Untwinned YBaCuO Single Crystals'
A.Rydh and \"O.Rapp [Phys. Rev. Lett. {\bf 86}, 1873 (2001).] claim that the
vortex liquid in untwinned YBaCuO crystals is correlated
above the melting transition, in striking contrast to previous work [D.L\'opez
{\it et al.}, Phys. Rev. Lett. {\bf 76}, 4034 (1996).]. In this Comment we
present new measurements using the same experimental technique on twinned and
untwinned YBaCuO crystals with similar overall
characteristics as those reported by Rydh and Rapp . The comparison of the
vortex correlation response in both cases indicates that the central conclusion
of their work is not correct. Our results reconfirm the work by L\'opez {\it et
al.} and points on the origin of the misinterpretation in the work of Rydh and
Rapp.Comment: comment on A.Rydh and \"O.Rapp, Phys. Rev. Lett. {\bf 86}, 1873
(2001). accepted in Phys. Rev. Let
Field evaluation of a simple fluorescence method for detection of viable Mycobacterium tuberculosis in sputum specimens during treatment follow-up.
Simple tuberculosis (TB) treatment monitoring tools are needed. We assessed the performance of fluorescein-diacetate (FDA) smear microscopy for detection of viable Mycobacterium tuberculosis in sputum specimens (n = 288) of TB cases under treatment compared to culture (17.4% culture positivity). FDA sensitivity was moderate (83.7% [95% confidence interval {CI}, 70.3 to 92.6]), and specificity was low (66.1% [59.5 to 72.2]). The good negative predictive value (94.8% [90.1 to 97.8]) and negative likelihood ratio (0.2) suggest using this method to rule out treatment failure in settings without access to culture
Simulations of Oligomeric Intermediates in Prion Diseases
We extend our previous stochastic cellular automata based model for areal
aggregation of prion proteins on neuronal surfaces. The new anisotropic model
allow us to simulate both strong beta-sheet and weaker attachment bonds between
proteins. Constraining binding directions allows us to generate aggregate
structures with the hexagonal lattice symmetry found in recently observed in
vitro experiments. We argue that these constraints on rules may correspond to
underlying steric constraints on the aggregation process. We find that monomer
dominated growth of the areal aggregate is too slow to account for some
observed doubling time-to-incubation time ratios inferred from data, and so
consider aggregation dominated by relatively stable but non-infectious
oligomeric intermediates. We compare a kinetic theory analysis of oligomeric
aggregation to spatially explicit simulations of the process. We find that with
suitable rules for misfolding of oligomers, possibly due to water exclusion by
the surrounding aggregate, the resulting oligomeric aggregation model maps onto
our previous monomer aggregation model. Therefore it can produce some of the
same attractive features for the description of prion incubation time data. We
propose experiments to test the oligomeric aggregation model.Comment: 8 pages, 10 figures For larger versions of several figures, see
http://asaph.ucdavis.edu/~dmobley and click on the prion paper lin
Supercooling of the disordered vortex lattice in Bi_2Sr_2CaCu_2O_8+d
Time-resolved local induction measurements near to the vortex lattice
order-disorder transition in optimally doped
BiSrCaCuO single crystals shows that the
high-field, disordered phase can be quenched to fields as low as half the
transition field. Over an important range of fields, the electrodynamical
behavior of the vortex system is governed by the co-existence of the two phases
in the sample. We interpret the results in terms of supercooling of the
high-field phase and the possible first order nature of the order-disorder
transition at the ``second peak''.Comment: 4 pages, 3 figures. Submitted to Nature, July 10th, 1999; Rejected
August 8th for lack of broad interest Submitted to Physical Review Letters
September 10th, 199
Freezing transition of the vortex liquid in anisotropic superconductors
We study the solid-liquid transition of a model of pancake vortices in
laminar superconductors using a density functional theory of freezing. The
physical properties of the system along the melting line are discussed in
detail. We show that there is a very good agreement with experimental data in
the shape and position of the first order transition in the phase diagram and
in the magnitude and temperature dependence of the magnetic induction jump at
the transition. We analyze the validity of the Lindemann melting criterion and
the Hansen-Verlet freezing criterion. Both criteria are shown to be good to
predict the phase diagram in the region where a first order phase transition is
experimentally observed.Comment: 9 pages, 10 figure
Male health and obesity – diagnostic and therapeutic approach
Obesity may present as a significant medical problem for any person, regardless of age or gender. In men obesity causes considerable psychological stress, sexual dysfunction, subfertility, hypogonadism and cardiovascular conditions. These problems may form numerous pathological associations between each other, creating a vicious circle. The main factors which influence male fertility and sexual function in obesity and metabolic syndrome are imbalance of sex hormones and systemic inflammation. In many patients symptomatic treatment is necessary for above-mentioned manifestations, but it is always rational to act on their pathophysiology and to recommend to lower the body mass by diet and lifestyle modification. When it proves impossible for the patient to follow such recommendations and when behavioral approach fails, central-acting and peripheral-acting medications may be used, including orlistat, sibutramine and liraglutide. Bariatric surgery should be offered to patients with high body mass index in whom conservative management fails. Without elimination of excess body mass it is difficult to solve problems regarding sexual dysfunction, hypogonadism and subfertility in obese males. All these issues and available modes of pharmacological treatment are described in this review
Dynamics of Flux Creep in Underdoped Single Crystals of Y_1-xPr_xBa_2Cu_3O_7-d
Transport as well as magnetic relaxation properties of the mixed state were
studied on strongly underdoped Y_1-xPr_xBa_2Cu_3O_7-d crystals. We observed two
correlated phenomena - a coupling transition and a transition to quantum creep.
The distribution of transport current below the coupling transition is highly
nonuniform, which facilitates quantum creep. We speculate that in the mixed
state below the coupling transition, where dissipation is nonohmic, the current
distribution may be unstable with respect to self-channeling resulting in the
formation of very thin current-carrying layers.Comment: 11 pages, 9 figures, Submitted to Phys. Rev.
Density-functional theory of freezing of vortex-liquid in quasi two-dimensional superconductors
We present a theory of vortex liquid-to-solid transition in homogeneous quasi
2D superconductors. The free energy is written as a functional l of density of
zeroes of the fluctuating order parameter. The transition is weakly first-order
and well below the Hc2(T) line. Transition temperature, discontinuities of the
average Abrikosov ratio and of the average superfluid density, the Debay-Waller
factor and the latent heat are in good agreement with Monte Carlo simulations.
The density is only weakly modulated in the "vortex-solid" phase, consistent
with the density-wave behavior.Comment: 12 pages and 1 figure available upon request, LaTex Version 2.09,
submitted to Phys. Rev. Let
Hydrodynamics and Nonlocal Conductivities in Vortex States of Type II Superconductors
A hydrodynamical description for vortex states in type II superconductors is
presented based on the time-dependent Ginzburg-Landau equation (TDGL). In
contrast to the familiar extension of a single vortex dynamics based on the
force balance, our description is consistent with the known hydrodynamics of a
rotating neutral superfluid and correctly includes informations on the
Goldstone mode. Further it enables one to examine nonlocal conductivities
perpendicular to the magnetic field in terms of Kubo formula. The nonlocal
conductivities deviate from the usual vortex flow expressions typically when
the nonlocality parallel to the field becomes weaker than the perpendicular one
measuring a degree of positional correlations, and, for instance, the
superconducting contribution of dc Hall conductivity nonlocal only in
directions perpendicular to the field becomes vanishingly small in the
situations with large shear viscosity, leading to an experimentally measurable
relation among the total resistivity components.
Other situations are also discussed on the basis of the resulting expressions.Comment: 12 pages, no figures, to appear in J. Phys. Soc. Jpn. in October,
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