132 research outputs found

    A Simple and Efficient Synthesis of 12-Aryl-8,9,10,12- tetrahydrobenzo[a]xanthen-11-ones by ZnO Nanoparticles Catalyzed Three Component Coupling Reaction of Aldehydes, 2-Naphthol and Dimedone

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    Highly effective zinc oxide nanoparticles catalyzed solvent-free synthesis of some tetrahydrobenzo[a]xanthen-11-one derivatives via one-pot multi-component reaction of aldehydes, 2-naphthol and dimedone. The present approach creates a variety of biologically active heterocyclic compounds in excellent yields and short reaction times. Four new compounds are reported. The salient features of the ZnO nanoparticles are: easy preparation, cost-effective, high stability, low loading and reusability of the catalyst. The prepared zinc oxide nanoparticles were fully characterized by EDX, XRD, SEM, IR and TEM analysis.KEYWORDS: ZnO, nanoparticles, tetrahydrobenzo[a]xanthen-11-one, multi-component reactions,  heterocyclic compounds

    FeCl3.nano SiO2: An Efficient Heterogeneous Nano Catalyst for the Synthesis of 14-Aryl-14H-dibenzo[a,j]xanthenes and 1,8-Dioxo-octahydro-xanthenes under Solvent-free Conditions

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    A novel, efficient and eco-friendly procedure for the synthesis of 14-aryl-14H-dibenzo[a,j]xanthenes and 1,8-dioxo-octahydroxanthenes is described through one-pot condensation of 2-naphthol and dimedone with aryl aldehydes in the presence of nano silica-supported ferric chloride under solvent-free conditions. The present approach offers several advantages such as short reaction times, high yields, easy purification, recovery and reusability of the catalyst.Keywords: Xanthenes, nano silica, ferric chloride, multi-component reactions, solvent-fre
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