Impact of Toxic Leadership, Marginalization, Favouritism, Ergonomics, and Servant Leadership on Human Capital Sustainability

The issue of toxic leadership, marginalization, and favoritism-(nepotism-cronyism) one of the important issues that represent risky phenomena and real problem that impact and results in many negative effects on the sustainability of human capital. But the question remains, which of these managerial and psychological variables affects the sustainability of human capital most? Is toxic leadership or marginalization or favoritism or ergonomics or servant leadership are the most or least impact on the sustainability of human capital? The research focused on a puzzling subject in managerial thought philosophy and studied six variables: toxic leadership, marginalization, favouritism- (nepotism-cronyism), ergonomics, and servant leadership and their impact on the sustainability of human capital. a sample of (371) Cairo international airport (CIA) employees. Finally, the study measured and determined the six most important variables that impacted the sustainability of human capital and tested the ten research hypotheses. Additionally, suggested some recommendations and implementation mechanisms that raise the efficiency of the airline sector and contribute to moderating the effects of toxic leadership, favoritism-(nepotism-cronyism) (FNC), and marginalization on employee performance and enhancing the role of servant leadership (SL), providing and improving ergonomics (workplace conditions and environment), which contributes to the sustainability of human capital (SHC)

Coupled THM analysis of long-term anisotropic convergence in the full-scale micro tunnel excavated in the Callovo-Oxfordian argillite

The main purpose of this paper is to analyse the convergence measurements of the ALC1604 in situ heating test carried out in the Callovo-Oxfordian claystone formation (COx) in the Meuse/Haute-Marne underground research laboratory (MHM URL). The concept of the test consists of horizontal micro-tunnel, equipped with a steel casing. The micro-tunnel is excavated in the direction of the horizontal principal major stress (sH). In situ observations showed anisotropic convergence with the maximum and minimum values in the horizontal and vertical directions, respectively. Coupled THM numerical analyses have been carried out to provide a structured framework for interpretation, and to enhance understanding of THM behaviour of Callovo-Oxfordian claystone. However, a special mechanical constitutive law is adopted for the description of the time-dependent anisotropic behaviour of the COx. The simulation of the test using this enhanced model provides a satisfactory reproduction of the THM long-term anisotropic convergence results. It also provides a better understanding of the observed test response.Postprint (published version

Constraining Lorentz-violating, Modified Dispersion Relations with Gravitational Waves

Modified gravity theories generically predict a violation of Lorentz invariance, which may lead to a modified dispersion relation for propagating modes of gravitational waves. We construct a parametrized dispersion relation that can reproduce a range of known Lorentz-violating predictions and investigate their impact on the propagation of gravitational waves. A modified dispersion relation forces different wavelengths of the gravitational wave train to travel at slightly different velocities, leading to a modified phase evolution observed at a gravitational-wave detector. We show how such corrections map to the waveform observable and to the parametrized post-Einsteinian framework, proposed to model a range of deviations from General Relativity. Given a gravitational-wave detection, the lack of evidence for such corrections could then be used to place a constraint on Lorentz violation. The constraints we obtain are tightest for dispersion relations that scale with small power of the graviton's momentum and deteriorate for a steeper scaling.Comment: 11 pages, 3 figures, 2 tables: title changed slightly, published versio

Thermo-hydro-mechanical simulation of a full-scale steel-lined micro-tunnel excavated in the callovooxfordian claystone

The paper presents an interpretation of the full-scale ALC1604 in situ heating test carried out in Callovo-Oxfordian claystone (COx) in the Meuse/Haute-Marne underground research laboratory (MHM URL). The MHM URL is a site-specific facility planned to study radioactive waste disposal in the COx. The thermo-hydro-mechanical (THM) behaviour of the host rock is significant for the design of the underground radioactive waste disposal facility and for its long-term safety. When subjected to thermal loading, the Callovo-Oxfordian claystone of low permeability (~10-20-10-21 m2) exhibits a strong pore pressure response that significantly affects the hydraulic and mechanical behaviour of the material. The observations gathered in the in situ test have provided an opportunity to examine the integrated thermo-hydromechanical (THM) response of this sedimentary clay. Coupled THM numerical analyses have been carried out to provide a structured framework for interpretation, and to enhance understanding of THM behaviour of COx. Numerical analyses have been based on a coupled theoretical formulation that incorporates a constitutive law specially developed for this type of material. The law includes a number of features that are relevant for a satisfactory description of the hydromechanical behaviour. By performing the numerical analysis, it has been possible to incorporate anisotropy of material parameters and of in situ stresses. The performance and analysis of the in situ tests have significantly enhanced the understanding of a complex THM problem and have proved the capability of the numerical formulation to provide adequate predictive capacity

Alterations in T1 of normal and reperfused infarcted myocardium after Gd-BOPTA versus GD-DTPA on inversion recovery EPI.

This study tested whether Gd-BOPTA/Dimeg or Gd-DTPA exerts greater relaxation enhancement for blood and reperfused infarcted myocardium. Relaxivity of Gd-BOPTA is increased by weak binding to serum albumin. Thirty-six rats were subjected to reperfused infarction before contrast (doses = 0.05, 0.1, and 0.2 mmol/kg). delta R1 was repeatedly measured over 30 min. Gd-BOPTA caused greater delta R1 for blood and myocardium than did Gd-DTPA; clearance of both agents from normal- and infarcted myocardium was similar to blood clearance; plots of delta R1 myocardium/delta R1 blood showed equilibrium phase contrast distribution. Fractional contrast agent distribution volumes were approximately 0.24 for both agents in normal myocardium, 0.98 and 1.6 for Gd-DTPA and Gd-BOPTA, respectively, in reperfused infarction. The high value for Gd-BOPTPA was ascribed to greater relaxivity in infarction versus blood. It was concluded that Gd-BOPTA/Dimeg causes a greater delta R1 than Gd-DTPA in regions which contain serum albumin

Analgesic and Anti-inflammatory Profile of n-Hexane Fraction of Viola betonicifolia

Purpose: To evaluate the analgesic and anti-inflammatory activities of n-hexane extract of the whole plant of Viola betonicifolia Sm, family: Violaceace.Methods: The n-hexane fraction of Viola betonicifolia (VBHF) was tested for its analgesic and antiinflammatory activities (carrageenan-induced and histamine-induced edema models) in BALB/c mice.Results: VBHF exhibited significant (p < 0.01) analgesic and anti-inflammatory activity at test doses of 100, 200 and 300 mg/kg. The analgesic effect of VBHF was dose-dependent in acetic acid pain modelwhile the extract was a weak analgesic at the dose of 300 mg/kg in hot plate and tail immersion test. Diclofenac sodium and tramadol showed better analgesic properties to the extract. Analgesia was not antagonized by naloxone in the hot plate model. Anti-inflammatory activity against carrageenan-induced edema was 60.8 %; however, histamine-induced inflammation was not antogonised by the extract.Conclusions: The extract has some analgesic and anti-inflammatory activities. This justifies its use in traditional medicine for pain of management.Keywords: Viola betonicifolia, Analgesic, Anti-inflammatory

Assessment of Heavy Metal Content of Branded Pakistani Herbal Products

Purpose: To investigate the heavy metals present in branded Pakistani herbal medicines used in the management of various human ailments.Method: The herbal dosage forms assessed were tablets, capsules and syrups. The samples were prepared for analysis by wet digestion method using nitric acid and perchloric acid treatment and then analyzed using a flame atomic absorption spectrometer.Results: Most of the products exceeded the permissible limits for lead (100 %), cadmium (68 %), chromium (96 %) and nickel (100 %). However, the contents of copper, manganese, zinc and iron were below toxic limits in several of the products. Some of the products, including Arq-e-badian, Bazori, Banafsha and Arq-Mako, exhibited toxic concentration of almost all the metals assessed.Conclusion: There is need to design suitable quality control parameters for the validation of herbal products and/or implement already existing rules and regulations for the safety of end-users.Keywords: Heavy metals, Branded herbal products, Validation, Toxicit

Climate change and ticks:measuring impact

This chapter focuses on the relationship between climate change and changes in tick abundance, phenology and disease incidence. It discusses evidences and limitations as well as novel tools (such as metabolic rate measurement) for detecting the impact of climate on ticks

Protective potential of methanol extract of Digera muricata on acrylamide induced hepatotoxicity in rats

This study was aimed to evaluate the probable protective effects of Digera muricata methanol extract (DME) against acrylamide (AA) induced hepatocellular injuries in female Sprague-Dawley rat. Phytochemical screening for the presence of different bioactive chemical groups was also carried out. The daily dose (6 mg/kg bw i.p.) injection of AA for 15 days caused significant increase in serum level of liver marker enzymes and metabolites: AST, ALT, ACP, ALP, LDH, BUN, creatinine, direct bilirubin and total bilirubin, while significant decrease in total protein and albumin. Hepatic level of antioxidant enzymes; CAT, POD, SOD, GSH-Px, GST and QR, and GSH contents were significantly decreased, while γ-GT and MDA was significantly increased. Treatment of DME (100, 150 and 200 mg/kg), dose dependently, ameliorated the toxicity of AA and the studied parameters were reversed towards the control level. Hepatic lesions induced with AA were reduced with DME treatment. Phytochemical screening indicates the presence of flavonoids, alkaloids, terpenoids, saponins, tannins, phlobatanin, coumarins, anthraquinones and cardiac glycosides. Total phenolic and flavonoids contents were 205±0.23 and 175.0±0.65 mg/g as equivalent to gallic acid and rutin, respectively in DME. In conclusion, the results suggest that the hepatoprotective effects of DME against AA-induced oxidative injuries could be attributed to the phenolics and flavonoids.Key words: Digera muricata, acrylamide, alanine aminotransferase, antioxidant enzymes, TBARS, flavonoids