Application of multirate digital filter banks to wideband all-digital phase-locked loops design

A new class of architecture for all-digital phase-locked loops (DPLL's) is presented in this article. These architectures, referred to as parallel DPLL (PDPLL), employ multirate digital filter banks (DFB's) to track signals with a lower processing rate than the Nyquist rate, without reducing the input (Nyquist) bandwidth. The PDPLL basically trades complexity for hardware-processing speed by introducing parallel processing in the receiver. It is demonstrated here that the DPLL performance is identical to that of a PDPLL for both steady-state and transient behavior. A test signal with a time-varying Doppler characteristic is used to compare the performance of both the DPLL and the PDPLL

Partially-Distributed Resource Allocation in Small-Cell Networks

We propose a four-stage hierarchical resource allocation scheme for the downlink of a large-scale small-cell network in the context of orthogonal frequency-division multiple access (OFDMA). Since interference limits the capabilities of such networks, resource allocation and interference management are crucial. However, obtaining the globally optimum resource allocation is exponentially complex and mathematically intractable. Here, we develop a partially decentralized algorithm to obtain an effective solution. The three major advantages of our work are: 1) as opposed to a fixed resource allocation, we consider load demand at each access point (AP) when allocating spectrum; 2) to prevent overloaded APs, our scheme is dynamic in the sense that as the users move from one AP to the other, so do the allocated resources, if necessary, and such considerations generally result in huge computational complexity, which brings us to the third advantage: 3) we tackle complexity by introducing a hierarchical scheme comprising four phases: user association, load estimation, interference management via graph coloring, and scheduling. We provide mathematical analysis for the first three steps modeling the user and AP locations as Poisson point processes. Finally, we provide results of numerical simulations to illustrate the efficacy of our scheme.Comment: Accepted on May 15, 2014 for publication in the IEEE Transactions on Wireless Communication

Treatment of Migraine: How Effective Is Biofeedback Assisted Relaxation Training?

ObjectiveBehavioral interventions such as relaxation training and biofeedback are some of the most effective interventions for management of migraine headaches. In this study we evaluated the utility of biofeedback-assisted progressive muscle relaxation training (PRT) in the treatment of migraine.Materials and MethodsIn this prospective study, twenty patients (12-18 years old) with a confirmed diagnosis of migraine headache, admitted to the Talie counseling center between March 2005 and December 2005, were evaluated; they were randomly assigned into an experimental group receiving biofeedback-assisted PRT and a control group in waiting list. All patients recorded the intensity of the headache and its frequency and duration before and 12 weeks after the treatment.ResultsThe data was analyzed using Independent sample t-test for mean differences.In the biofeedback-assisted progressive muscle relaxation trained group, a statistically and clinically significant decrease was detected in intensity (pConclusionIt can be concluded that biofeedback-assisted progressive muscle relaxation training is a successful form of therapy in treatment of migraine

2D:4D Suggests a Role of Prenatal Testosterone in Gender Dysphoria

Gender dysphoria (GD) reflects distress caused by incongruence between one’s experienced gender identity and one’s natal (assigned) gender. Previous studies suggest that high levels of prenatal testosterone (T) in natal females and low levels in natal males might contribute to GD. Here, we investigated if the 2D:4D digit ratio, a biomarker of prenatal T effects, is related to GD. We first report results from a large Iranian sample, comparing 2D:4D in 104 transwomen and 89 transmen against controls of the same natal sex. We found significantly lower (less masculine) 2D:4D in transwomen compared to control men. We then conducted random-effects meta-analyses of relevant studies including our own (k = 6, N = 925 for transwomen and k = 6, N = 757 for transmen). In line with the hypothesized prenatal T effects, transwomen showed significantly feminized 2D:4D (d ≈ 0.24). Conversely, transmen showed masculinized 2D:4D (d ≈ − 0.28); however, large unaccounted heterogeneity across studies emerged, which makes this effect less meaningful. These findings support the idea that high levels of prenatal T in natal females and low levels in natal males play a part in the etiology of GD. As we discuss, this adds to the evidence demonstrating the convergent validity of 2D:4D as a marker of prenatal T effects

Anomalous left brachiocephalic vein: important vascular anomaly concomitant with congenital anomalies and heart diseases

Background: Anomalous left brachiocephalic vein (ALBCV) is a rare and less known systemic venous anomaly. Infrequently, this vein takes an abnormal course and passes to the right behind or beneath the aortic arch to create the superior vena cava (SVC). Its incidence was reported much higher in patients with congenital heart disease especially in conotruncal and aortic arch anomalies. It could be misdiagnosed with normal or abnormal mediastinal structures. It also could make complication during surgeries or invasive strategies. Previously, this anatomical finding has been reported in case reports and there are just few studies evaluating these patients as a group to find other abnormalities Materials and methods: We conducted a retrospective, multicentre study between 2008 and 2014 at three institutions. We reviewed thoracic computed tomography angiography of 1372 patients referred to these centres. The diagnosis of ALBCV was confirmed by an expert radiologist and the imagings were reassessed to identify new cases and concomitant anomalies. We analysed the imagings’ details and measured the prevalence of each anomaly. Results: Among the 22 cases of ALBCV, 12 (54.5%) and 10 (45.4%) patients were males and females, respectively, with median age of 12.5 years. Tetralogy of Fallot (TOF) was considered as a most concomitant anomaly with ALBCV (54.5%). Two patients had associated atrial septal defect (ASD) and defined as pentalogy of Fallot. Right-sided aortic arc (RSAA) was detected in 12 (54.5%) patients; mirror image was found in 5 of them. Pure ventricular septal defect or pulmonary stenosis without TOF was recognised in 4 patients. Three cases had isolated overriding aorta (13.6%). In 3 patients, we could find patent ductus arteriosus (13.6%). In 2 (9%) patients, abdominal haemangioma was incidentally diagnosed. Aberrant left retrotracheal subclavian artery was detected in 1 (4.5%) patient. One patient only had isolated ALBCV (4.5%). Conclusions: In our study, ALBCV was frequently seen in association with other congenital anomalies. mostly TOF and RSAA. In patients with pulmonary hypoplasia or aplasia, some parts of lung’s blood supply were provided by abnormal aorto-pulmonary connections. For a radiologist, it is important to differentiate this anomaly in cross-sectional imaging from persistent left SVC, partial anomalous pulmonary veins return and an enlarged lymph node. Detection of ALBCV could draw the attention to the more serious heart disease and in isolated forms prevented further evaluations.