Lateralization of mesial temporal lobe epilepsy with chronic ambulatory electrocorticography

OBJECTIVE: Patients with suspected mesial temporal lobe (MTL) epilepsy typically undergo inpatient video-electroencephalography (EEG) monitoring with scalp and/or intracranial electrodes for 1 to 2 weeks to localize and lateralize the seizure focus or foci. Chronic ambulatory electrocorticography (ECoG) in patients with MTL epilepsy may provide additional information about seizure lateralization. This analysis describes data obtained from chronic ambulatory ECoG in patients with suspected bilateral MTL epilepsy in order to assess the time required to determine the seizure lateralization and whether this information could influence treatment decisions. METHODS: Ambulatory ECoG was reviewed in patients with suspected bilateral MTL epilepsy who were among a larger cohort with intractable epilepsy participating in a randomized controlled trial of responsive neurostimulation. Subjects were implanted with bilateral MTL leads and a cranially implanted neurostimulator programmed to detect abnormal interictal and ictal ECoG activity. ECoG data stored by the neurostimulator were reviewed to determine the lateralization of electrographic seizures and the interval of time until independent bilateral MTL electrographic seizures were recorded. RESULTS: Eighty-two subjects were implanted with bilateral MTL leads and followed for 4.7 years on average (median 4.9 years). Independent bilateral MTL electrographic seizures were recorded in 84%. The average time to record bilateral electrographic seizures in the ambulatory setting was 41.6 days (median 13 days, range 0-376 days). Sixteen percent had only unilateral electrographic seizures after an average of 4.6 years of recording. SIGNIFICANCE: About one third of the subjects implanted with bilateral MTL electrodes required >1 month of chronic ambulatory ECoG before the first contralateral MTL electrographic seizure was recorded. Some patients with suspected bilateral MTL seizures had only unilateral electrographic seizures. Chronic ambulatory ECoG in patients with suspected bilateral MTL seizures provides data in a naturalistic setting, may complement data from inpatient video-EEG monitoring, and can contribute to treatment decisions

Accessing Data: methods for understanding mobile technology use

Mobile devices, applications and services have become integrated into people’s daily lives on a personal and professional level. Although traditional research methods are being used to understand the use of mobile devices and applications, methodological challenges still exist. Researchers have responded to these challenges in a variety of ways, with an emphasis on developing methods that enable new ways of accessing, making available and collecting data about mobile technology use. This paper identifies, defines, describes and presents, a preliminary framework for understanding the methodological responses emerging in current Mobile Human Computer Interaction (Mobile HCI) researc

Designing a Movement-Based Interactive Experience Using Empirically Derived Personas and Scenarios

This research project draws together two areas; interactive art and Human-Computer Interaction (HCI). This paper describes the data collection of audience behaviour in a variety of museum and gallery locations. Subsequent data analysis leading to persona and scenario design illustrates how empirical data can inform the design of a movementbased interface. Finally, low level prototypes were developed to aid the artist/ designers in their aims to create an interactive installation in which visitors could learn contextually driven behaviour

ACCESSING DATA: METHODS FOR UNDERSTANDING MOBILE TECHNOLOGY USE

Mobile devices, applications and services have become integrated into people’s daily lives on a personal and professional level. Although traditional research methods are being used to understand the use of mobile devices and applications, methodological challenges still exist. Researchers have responded to these challenges in a variety of ways, with an emphasis on developing methods that enable new ways of accessing, making available and collecting data about mobile technology use. This paper identifies, defines, describes and presents, a preliminary framework for understanding the methodological responses emerging in current Mobile Human Computer Interaction (Mobile HCI) research

The Efficacy and Cost-Effectiveness of Replacing Whole Apples with Sliced in the National School Lunch Program

The National School Lunch Program (NSLP) serves 29.6 million lunches each day. Schools must offer ½ a cup of fruit for each lunch tray. Much of this fruit may be wasted, leaving the schools in a dilemma. The objectives of this study were to evaluate the consumption of whole vs. sliced apples and determine the cost-effectiveness of the intervention. Researchers weighed apple waste at baseline and three post-intervention time points in one rural Midwest school. The costs of the intervention were collected from the school. The cost-effectiveness analysis estimates how often apples need to be served to offset the costs of the slicing intervention. A total of (n = 313) elementary student students participated. Students consumed significantly more sliced as compared to whole apples in intervention months 3 (β = 21.5, p < 0.001) and 4 (β = 27.7, p < 0.001). The intervention cost was USD 299. The value of wasted apple decreased from USD 0.26 at baseline to USD 0.23 wasted at post-intervention. The school would need to serve 9403 apples during the school year (54 times) to cover the expenses of the intervention. In conclusion, serving sliced apples may be a cost-effective way to improve fruit consumption during school lunch