The diagnosis and clinical importance of tumour neovascularisation from coronary artery to right atrial myxoma

Myxomas are the commonest cardiac tumours and are usually localised in the atria. Neovascularisation in cardiac myxomas has been shown in previous case reports. However, the clinical importance of neovascularisation in cardiac myxomas is not well understood. In our case report, we present a right atrial myxoma in a 46 year-old woman admitted to our hospital with exertional angina and dyspnea. Coronary angiography revealed the presence of tumour neovascularisation from the right coronary artery, with no evidence of coronary artery stenosis. We thus speculate that neovascularisation of myxoma may cause typical anginal symptoms as a result of coronary steal phenomenon. Coronary angiography might help in the evaluation of the neovascularisation process and also in indicating surgery.Myxomas are the commonest cardiac tumours and are usually localised in the atria. Neovascularisation in cardiac myxomas has been shown in previous case reports. However, the clinical importance of neovascularisation in cardiac myxomas is not well understood. In our case report, we present a right atrial myxoma in a 46 year-old woman admitted to our hospital with exertional angina and dyspnea. Coronary angiography revealed the presence of tumour neovascularisation from the right coronary artery, with no evidence of coronary artery stenosis. We thus speculate that neovascularisation of myxoma may cause typical anginal symptoms as a result of coronary steal phenomenon. Coronary angiography might help in the evaluation of the neovascularisation process and also in indicating surgery

Quadrichambered ventricles

Double chambered is a term that has been used to describe the subdivision of a ventricle as a result of anomalous septum or muscle bundle. Subdivision of the left ventricular cavity is a rare cardiac anomaly compared to subdivision of the right ventricle. This case features a double chambered right ventricle and a rare double chambered left ventricle at the same time. (Cardiol J 2010; 17, 3: 303–305

Trombektomia aspiracyjna w zagrażającej dystalnej makrozatorowości podczas przezskórnej interwencji wieńcowej

Percutaneous coronary interventions (PCI) of thrombus-containing lesions are associated with increased risk of complications such as distal coronary embolisation and impaired coronary circulation. Although the use of thrombectomy devices to aspirate thrombus during primary PCI is currently not routinely recommended, there is growing evidence suggesting the use of thrombus aspiration catheters during PCI. Here, we report the case of a 70 year-old patient undergoing thrombus aspiration therapy because of the development of coronary bifurcation macroemboli during initial phase of primary PCI. After successful thrombus aspiration therapy, dramatic improvements in both coronary flow and ST-segment resolution were achieved. Kardiol Pol 2011; 69, 4: 400-40

INADVERTENT COMPLICATION OF PROSTHETIC VALVE SURGERY: LEAFLET PERFORATION

There are various complications of prosthetic valvular surgeries. Among them, leaflet perforation should be emphasized and brought to mind when there have been eccentric valvular regurgitation. In this report, we presented 2 cases of iatrogenic aortic and mitral valve leaflet perforation after prosthetic valve surgeries

Quadrichambered Ventricles

Double chambered is a term that has been used to describe the subdivision of a ventricle as a result of anomalous septum or muscle bundle. Subdivision of the left ventricular cavity is a rare cardiac anomaly compared to subdivision of the right ventricle. This case features a double chambered right ventricle and a rare double chambered left ventricle at the same time. (Cardiol J 2010; 17, 3: 303-305)Wo

Evaluation of Heart Rate Turbulence Parameters According to Localization of Infarction in Patients with ST-elevation MI who Underwent Primary Percutaneous Coronary Intervention

29th Turkish Cardiology Congress of the Turkish-Society-of-Cardiology (TSC) with International Participation -- OCT 26-29, 2013 -- Antalya, TURKEYWOS: 000329858400338Turkish Soc Cardio

Artykuł oryginalnyZwiązek pomiędzy aktywnością paraoksonazy a późną niedrożnością pomostów żylnych u chorych poddawanych chirurgicznej rewaskularyzacji wieńcowej

Background: Coronary vein graft disease is an important contributor to the morbidity after coronary artery bypass grafting (CABG). Late occlusion of the graft is a serious complication that limits the use of the saphenous vein as a coronary bypass conduit. It is frequently encountered in old, degenerated vein grafts with advanced atherosclerotic plaque formation. Paraoxonase-1 (PON-1) is an HDL-bound enzyme which has anti-atherogenic properties and protects LDL cholesterol from oxidative modification. Aim: To examine the association between PON-1 activity and late saphenous vein graft occlusion. Methods: Thirty-eight patients who had at least one occluded saphenous vein graft (group 1; 12 females, 26 males) and 41 patients who had a patent saphenous vein graft (group 2; 7 females, 34 males) were enrolled in this study. Paraoxonase activity was measured spectrophotometrically. Results: The mean PON-1 activity in group 1 was significantly lower than in group 2 (74.1 ± 52.1 vs. 114.4 ± 90.9 U/l, p = 0.02). The mean platelet volume was significantly higher in group 1 than group 2 (8.8 ± 1.6 vs. 8.2 ± 1.1 fl, p = 0.04). Multiple logistic regression analysis showed that only PON-1 activity (beta = 0.011, p = 0.042) was an independent predictor of late occlusion of a saphenous vein graft. Conclusions: Our results show that PON-1 activity is lower in patients with late saphenous vein graft occlusion. Reduced PON-1 activity may lead to acceleration of saphenous vein graft occlusion.Wstęp: Zwężenie żylnego pomostu aortalno-wieńcowego jest istotnym powikłaniem chirurgicznej rewaskularyzacji wieńcowej (CABG). Późne zamknięcie pomostu jest poważnym powikłaniem, ograniczającym szerokie stosowanie żylnych pomostów u wszystkich chorych. Najczęściej dochodzi do niego w żylnych pomostach wszczepionych wiele lat temu, w których rozwijają się blaszki miażdżycowe. Paraoksonaza 1 (PON-1) jest enzymem wiążącym HDL, który działa przeciwmiażdżycowo, ochraniając LDL-cholesterol przed utlenianiem. Cel: Zbadanie związku pomiędzy aktywnością PON-1 a późnym zamknięciem pomostu żylnego. Metody: Do badania włączono 38 chorych z co najmniej jednym zamkniętym pomostem żylnym (grupa 1 – 12 kobiet, 26 mężczyzn) i 41 chorych z drożnym pomostem żylnym (grupa 2 – 7 kobiet, 34 mężczyzn). Aktywność PON-1 mierzono metodą spektrofotometryczną. Wyniki: Średnia aktywność PON-1 w grupie 1 była istotnie niższa niż w grupie 2 (74,1 ± 52,1 vs 114,4 ± 90,9 U/l, p = 0,02), natomiast średnia objętość płytek krwi była istotnie wyższa w grupie 1 niż 2 (8,8 ± 1,6 vs 8,2 ± 1,1 fl, p = 0,04). Wieloczynnikowa analiza regresji wykazała, że aktywność PON-1 była jedynym niezależnym czynnikiem związanym z późnym zamknięciem żylnego pomostu aortalno- -wieńcowego (b = 0,011, p = 0,042). Wnioski: Aktywność PON-1 jest mniejsza u chorych z zamkniętym pomostem żylnym, co może wskazywać, że zmniejszona aktywność tego enzymu przyspiesza zamknięcie żylnych pomostów aortalno-wieńcowych