1,211 research outputs found

    Reduced contribution of the ipsilateral primary motor cortex to force modulation with short-term motor learning in humans: An NIRS study

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    How is muscle force modulated during hand exercise? Oxygenation in the contralateral primary motor cortex (M1) has been observed to vary considerably across trials of repetitive handgrip exercise. No linear relationship was observed between the average value of oxygenation determined by a block design study and the force of the handgrip. We found reduced oxygenation in the ipsilateral M1 and unchanged oxygenation in the contralateral M1 during repetitive static handgrip exercises (40% and 60% maximal voluntary contraction; 10 s exercise/75 s rest; 5 sets), which might be due to short-term motor learning. These results support the hypothesis that the ipsilateral M1 might functionally compensate for the contralateral M1 in force modulation during unilateral exercises

    Nature of cultured cells of the skin from acatalasemic individuals with Takahara's disease

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    For the purpose to clarify whether minimal catalatic activity exists in Japanese acatalasemic cells or not and the manner how extrinsic hydrogen peroxide affects the acatalasemic cells, the author performed tissue cultures using the skin specimens from four acatalasemic persons affected with Takahara's disease and studied the nature of these cultured cells. The results are summarized as follows. 1. Between normal and acatalasemic cultured cells, no morphological differences could be seen and the growth rate of these cell-lines was similar to one another. 2. On the activity of succinoxidase and cytochrome oxidase there could be observed no difference between normal and acatalasemic cells. 3. In each acatalasemic cell line the minimal catalatic activity was observed and it seemed that this activity has an important role in decomposing hydrogen peroxide under normal metabolic pathway. 4. After treating with 10-4M hydrogen peroxide, respiratory enzyme activities and the growth rate in the acatalasemic cells were markedly disturbed, while in normal cells these remained almost intact. 5. There could be observed no differences between normal and acatalasemic cultured cells after X-ray irradiation (200 to 600 r) on the succinoxidase activity, catalatic activity and growth rate.</p

    Weak Resilience of Networked Control Systems

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    In this paper, we propose a method to establish a networked control system that maintains its stability in the presence of certain undesirable incidents on local controllers. We call such networked control systems weakly resilient. We first derive a necessary and sufficient condition for the weak resilience of networked systems. Networked systems do not generally satisfy this condition. Therefore, we provide a method for designing a compensator which ensures the weak resilience of the compensated system. Finally, we illustrate the efficiency of the proposed method by a power system example based on the IEEE 14-bus test system

    Radio-frequency confinement of the plasma trapped in a minimum B magnetic mirror field

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    Thesis--University of Tsukuba, D.Sc.(A), no. 151, 1982. 3. 2

    Successful resection of liver metastasis detected by exacerbation of skin symptom in a patient with dermatomyositis accompanied by rectal cancer: a case report and literature review

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    Abstract Background Dermatomyositis (DM) is a rare syndrome that belongs to the group of idiopathic inflammatory myopathies. The association between DM and malignancy is well recognized, and the severity of DM symptoms has been linked to the progression of metastatic disease. Case presentation We report the case of a 42-year-old man that was diagnosed with dermatomyositis (DM) and rectal cancer. Proctectomy was performed, and DM symptoms were resolved postoperatively. One year and 9\ua0months after the surgery, liver metastasis occurred accompanied by the exacerbation of DM symptom. Partial resection of the liver was performed, and postoperative course was uneventful. DM symptoms improved postoperatively, and no evidence of cancer recurrence or DM symptoms was observed 2\ua0years after the second surgery. To date, few reports have described recurring cases of DM accompanied by colorectal cancer in detail. We reviewed four similar cases that were reported poor prognoses with treatment resistance. However, our case report demonstrates good long-term results with resection of metastatic lesion. Conclusions It is important to check the exacerbation of DM symptoms, as this symptom sometimes preceded cancer relapse during the follow-up of our patient with DM and colorectal cancer

    F. Scott Fitzgerald and The Great Gatsby

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    application/pdf大阪府立大学紀要(人文・社会科学). 1966, 14, p.11-20departmental bulletin pape

    Characterization of Alloantigen Specific Human Suppressor T Cells Generated in Mixed Leukocyte Culture (MLC)

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    The mixed leukocyte culture (MLC) extended to 11 days provides the best source of allospecific suppressor T cell (Ts) as these cultures no longer autostimulate fresh autologous responder cells and have little cytotoxic activity. The suppressor assay is performed by adding these culture primed Ts to flat-bottom microwell cultures of fresh autologous lymphocytes responding to the same stimulator cells used for Ts induction. These Ts are radioresistant similar to the naturally occurring human Ts of the MLC. The phenotype of the Ts generated in this model is CD2+, CD8+ and 9.3+. No suppressor activity is found in the lymphocyte subset bearing the CD4 antigen. Studies on the antigen specificity of these alloactivated Ts povide formal evidence that not only Class II but also Class I HLA antigens can suffice as the target antigen(s). Preliminary data is provided to suggest that there are HLA antigens to which a given individual will easily make Ts and HLA antigens to which that individual will not readily produce Ts. It is suggested that this may be due to the genetic background of the responder and thus may be under Ir gene control as in the mouse. The antigen specificity of these Ts has been demonstrated by their failure to suppress the response of autologous lymphocytes to stimulator cells bearing unrelated alloantigens present in the same cultures. However, suppression of the response to unrelated alloantigens can be produced by presentation of those antigen(s) on the same cell bearing the suppressor inducer target antigen

    Measurement of the Decay KL -> Pi0 Gamma Gamma

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    We report on a new measurement of the decay KL -> pi0 gamma gamma by the KTeV experiment at Fermilab. We determine the KL -> pi0 gamma gamma branching ratio to be (1.68 +/- 0.07 +/- 0.08)x10**-6. Our data shows the first evidence for a low-mass gamma gamma signal as predicted by recent O(p**6) chiral perturbation calculations that include vector meson exchange contributions. From our data, we extract a value for the effective vector coupling aV = -0.72 +/- 0.05 +/- 0.06.Comment: 5 pages, 4 figure

    Observation of the Decay KLμ+μγγK_L\to \mu^+\mu^- \gamma \gamma

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    We have observed the decay KLμ+μγγK_L\to \mu^+\mu^- \gamma \gamma at the KTeV experiment at Fermilab. This decay presents a formidable background to the search for new physics in KLπ0μ+μK_L\to\pi^0\mu^+\mu^-. The 1997 data yielded a sample of 4 signal events, with an expected background of 0.155 ±\pm 0.081 events. The branching ratio is B(KLμ+μγγ{\mathcal B}(K_L\to \mu^+\mu^- \gamma \gamma) =(10.45.9+7.5(stat)±0.7(sys))×109 = (10.4^{+7.5}_{-5.9} {\rm (stat)} \pm 0.7 {\rm (sys)})\times 10^{-9} with mγγ1MeV/c2m_{\gamma\gamma} \geq 1 {\rm MeV/c}^2, consistent with a QED calculation which predicts (9.1±0.8)×109(9.1\pm 0.8)\times 10^{-9}.Comment: See also the paper "Search for the Decay KLπ0μ+μK_L \to \pi^0 \mu^+ \mu^-", also by the KTeV collaboratio
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