214 research outputs found

    Unpacking the Spice; Understanding Reproductive Health in Grenada

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    Global Independent Study, Summer 2017 -- Grenada -- Partner Agencie(s): Grenada Planned Parenthood Associationhttps://deepblue.lib.umich.edu/bitstream/2027.42/138993/1/Richardson_Poster.pd

    The Gatekeepers of the Black Press

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    Abstract Not Availabl

    Hue Magazine

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    HUE magazine is a print title dedicated toward the uplift and synergy of women of color in America. At present, there is no publication that makes a conscious effort to not single out women of color in specific ethnic groups, but instead to talk to all of them simultaneously. At its core, HUE’s target audience is first generation women of color between the ages of 18-25. It is a lifestyle magazine with stories in fashion, beauty, love, culture, health, entrepreneurship, and more. The goal is for the magazine to appeal to the girl in us all who loves fashion and beauty. But it also aims to appeal to support and challenge the ambitious, self-actualizing, persevering spirit present within us all. The magazine is designed to be a place of comfort, but also a place of discovery where women can see people who look like them and see a piece of themselves in people who don’t. This project was created with the help of writers, photographers, and graphics designers. There is original photography throughout the book in the fashion and beauty sections, culture sections, and more. The design is original and was created to best reflect the HUE vision and audience. Two Syracuse University juniors who were inspired by the project aim to create a publication similar to HUE which will debut in the Fall 2012-Spring 2013 school year

    Aspects of the biological integrity of the rivers flowing into the hyper-eutrophic Roodeplaat Dam : a comparative study

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    Abstract : Please refer to full text to view abstract.D.Phil. (Environmental Management

    Occupation Based Program for African American Crossover Youth Aging Out of Foster Care

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    Unique challenges and differences surround the population of African American crossover youth and how they successfully transition into adulthood once aged out of foster care as compared to same-aged peers (Kim et al., 2019). The problem is that African American crossover youth aging out of the foster care system, are not receiving occupation-based transitional services focusing on IADLs required for adulthood independence resulting in increased prevalence of homelessness (Armstrong-Heimsoth et al., 2020; Flores et al., 2018; Kelly, 2020; Paul-Ward & Lambdin-Pattavina, 2016; Pérez et al., 2019). The purpose of this program development type project is to develop and implement an occupation-based transitional program for African American crossover youth aging out of the foster care system focused on IADLs required for adulthood independence, decreasing the prevalence of homelessness. An occupation-based program is essential in providing more programs for youth during those transitional ages to increase self-sufficiency into adulthood. The occupation-based program focusing on IADLs and health management, #Adulting, was successful based on the positive feedback from each activity.https://soar.usa.edu/otdcapstonesfall2021/1029/thumbnail.jp

    Pharmacogenetics/genomics and personalized medicine

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    The development of a faecal incontinence core outcome set: an international Delphi study protocol

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    Purpose Faecal incontinence (FI) is estimated to affect around 7.7% of people. There is a lack of uniformity in outcome definitions, measurement and reporting in FI studies. Until now, there is no general consensus on which outcomes should be assessed and reported in FI research. This complicates comparison between studies and evidence synthesis, potentially leading to recommendations not evidence-based enough to guide physicians in selecting an FI therapy. A solution for this lack of uniformity in reporting of outcomes is the development of a Core Outcome Set (COS) for FI. This paper describes the protocol for the development of a European COS for FI. Methods Patient interviews and a systematic review of the literature will be performed to identify patient-, physician- and researcher-oriented outcomes. The outcomes will be categorised using the COMET taxonomy and put forward to a group of patients, physicians (i.e. colorectal surgeons, gastroenterologists and general practitioners) and researchers in a Delphi consensus exercise. This exercise will consist of up to three web-based rounds in which participants will prioritise and condense the list of outcomes, which is expected to result in consensus. A consensus meeting with participants from all stakeholder groups will take place to reach a final agreement on the COS. Discussion This study protocol describes the development of a European COS to improve reliability and consistency of outcome reporting in FI studies, thereby improving evidence synthesis and patient care

    Establishment and Characterization of an In Vitro Model for Cholesteatoma

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    ObjectivesExperimental models are of importance to study the pathogenesis of middle ear cholesteatoma, however, they were not established until now. We aimed to develop in vitro model of middle ear cholesteatoma using primary keratinocytes and fibroblasts isolated from cholesteatoma tissue. HaCaT cell line was used as a "skin equivalent" and to compare the grade of homogeneity between cholesteatoma keratinocytes and HaCaT cells.MethodsPrimary keratinocytes were isolated from cholesteatoma tissue, co-cultured with preliminary prepared feeder layer from cholesteatoma fibroblasts and subsequently air-exposed. The protein profile of cholesteatoma keratinocytes and HaCaT cells was evaluated by means of immunoblot using monoclonal antibody against cytokeratin (CK) 13 and 16. Tissue localization of CK 13 and 16 was accomplished with immunohistochemistry.ResultsDifferent protein profile and stronger expression of CK 13 and 16 were demonstrated in cholesteatoma keratinocytes in comparison with HaCaT cells. Bigger stratification was observed in the 3D-in vitro systems when both cholesteatoma keratinocytes and HaCaT cells were respectively co-cultured with fibroblasts in comparison with the corresponding control groups without fibroblasts.Conclusion3D-model demonstrates the significance of intercellular interaction between components of cholesteatoma tissue

    Guideline for the diagnosis and treatment of Faecal Incontinence-A UEG/ESCP/ESNM/ESPCG collaboration

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    INTRODUCTION The goal of this project was to create an up-to-date joint European clinical practice guideline for the diagnosis and treatment of faecal incontinence (FI), using the best available evidence. These guidelines are intended to help guide all medical professionals treating adult patients with FI (e.g., general practitioners, surgeons, gastroenterologists, other healthcare workers) and any patients who are interested in information regarding the diagnosis and management of FI. METHODS These guidelines have been created in cooperation with members from the United European Gastroenterology (UEG), European Society of Coloproctology (ESCP), European Society of Neurogastroenterology and Motility (ESNM) and the European Society for Primary Care Gastroenterology (ESPCG). These members made up the guideline development group (GDG). Additionally, a patient advisory board (PAB) was created to reflect and comment on the draft guidelines from a patient perspective. Relevant review questions were established by the GDG along with a set of outcomes most important for decision making. A systematic literature search was performed using these review questions and outcomes as a framework. For each predefined review question, the study or studies with the highest level of study design were included. If evidence of a higher-level study design was available, no lower level of evidence was sought or included. Data from the studies were extracted by two reviewers for each predefined important outcome within each review question. Where possible, forest plots were created. After summarising the results for each review question, a systematic quality assessment using the GRADE (Grading of Recommendations, Assessment, Development and Evaluations) approach was performed. For each review question, we assessed the quality of evidence for every predetermined important outcome. After evidence review and quality assessment were completed, recommendations could be formulated. The wording used for each recommendation was dependent on the level of quality of evidence. Lower levels of evidence resulted in weaker recommendations and higher levels of evidence resulted in stronger recommendations. Recommendations were discussed within the GDG to reach consensus. RESULTS These guidelines contain 45 recommendations on the classification, diagnosis and management of FI in adult patients. CONCLUSION These multidisciplinary European guidelines provide an up-to-date comprehensive evidence-based framework with recommendations on the diagnosis and management of adult patients who suffer from FI
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