7,985 research outputs found
Communications Biophysics
Contains report on one research project.National Institutes of Health (Grant 2 PO1 MH-04737-06)Joint Services Electronics Programs (U.S. Army, U.S. Navy, and U.S. Air Force) under Contract DA 36-039-AMC-03200(E)National Science Foundation (Grant GK-835)National Aeronautics and Space Administration (Grant NsG-496
Adhesion and electronic structure of graphene on hexagonal boron nitride substrates
We investigate the adsorption of graphene sheets on h-BN substrates by means
of first-principles calculations in the framework of adiabatic connection
fluctuation-dissipation theory in the random phase approximation. We obtain
adhesion energies for different crystallographic stacking configurations and
show that the interlayer bonding is due to long-range van der Waals forces. The
interplay of elastic and adhesion energies is shown to lead to stacking
disorder and moir\'e structures. Band structure calculations reveal substrate
induced mass terms in graphene which change their sign with the stacking
configuration. The dispersion, absolute band gaps and the real space shape of
the low energy electronic states in the moir\'e structures are discussed. We
find that the absolute band gaps in the moir\'e structures are at least an
order of magnitude smaller than the maximum local values of the mass term. Our
results are in agreement with recent STM experiments.Comment: 8 pages, 8 figures, revised and extended version, to appear in Phys.
Rev.
Extended conjugated microporous polymers for photocatalytic hydrogen evolution from water
Conjugated microporous polymers (CMPs) have been used as photocatalysts for hydrogen production from water in the presence of a sacrificial electron donor. The relative importance of the linker geometry, the co-monomer linker length, and the degree of planarisation were studied with respect to the photocatalytic hydrogen evolution rate
Reforming Reimbursement for the US Food and Drug Administration’s Accelerated Approval Program to Support State Medicaid Programs
Importance The US Food and Drug Administration (FDA) has an accelerated approval program that has become the subject of scholarly attention and criticism, not only for the FDA’s oversight of the program but also for its implications for payers.
Observations State Medicaid programs’ legal obligations to provide reimbursement for accelerated approval products have created fiscal challenges for Medicaid that have been exacerbated by industry’s changing use of the accelerated approval program over time. Although strategies for accelerated approval reforms have been proposed, most focus on reforming the FDA’s accelerated approval pathway and product regulation without taking into account the implications of this pathway for state Medicaid programs. There is a need for policy reforms that balance the goal of speeding approval of important medicines with states’ real concerns regarding spending on medications with little evidence of clinical benefits. Areas of potential reform include formulary exclusion, Medicaid rebates, value-based pricing, and consolidated purchasing or carve outs.
Conclusions and Relevance Policy makers may wish to consider options for reforming reimbursement for accelerated approval products in addition to reforms to the FDA’s operation of the pathway. Policy reform proposals can provide a range of options to evaluate trade-offs of access and pricing
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A Structural Analysis of Chile's Long-Term Growth: History, Prospects and Policy Implications
A Riemann-Hilbert Problem for an Energy Dependent Schr\"odinger Operator
\We consider an inverse scattering problem for Schr\"odinger operators with
energy dependent potentials. The inverse problem is formulated as a
Riemann-Hilbert problem on a Riemann surface. A vanishing lemma is proved for
two distinct symmetry classes. As an application we prove global existence
theorems for the two distinct systems of partial differential equations
for suitably restricted,
complementary classes of initial data
A note on the uniqueness of global static decompositions
We discuss when static Killing vector fields are standard, that is, leading
to a global orthogonal splitting of the spacetime. We prove that such an
orthogonal splitting is unique whenever the natural space is compact. This is
carried out by proving that many notable spacelike submanifolds must be
contained in an orthogonal slice. Possible obstructions to the global splitting
are also considered.Comment: 6 pages, no figure
symmetry and quasi-normal modes in the BTZ black hole
With the help of two new intrinsic tensor fields associated with the
quadratic Casimir of Killing fields, we uncover the
symmetry satisfied by the solutions to the equations of motion for various
fields in the BTZ black hole in a uniform way by performing tensor and spinor
analysis without resorting to any specific coordinate system. Then with the
standard algebraic method developed recently, we determine the quasi-normal
modes for various fields in the BTZ black hole. As a result, the quasi-normal
modes are given by the infinite tower of descendants of the chiral highest
weight mode, which is in good agreement with the previous analytic result
obtained by exactly solving equations of motion instead.Comment: JHEP style, 1+13 pages, version to appear in JHE
Akns Hierarchy, Self-Similarity, String Equations and the Grassmannian
In this paper the Galilean, scaling and translational self--similarity
conditions for the AKNS hierarchy are analysed geometrically in terms of the
infinite dimensional Grassmannian. The string equations found recently by
non--scaling limit analysis of the one--matrix model are shown to correspond to
the Galilean self--similarity condition for this hierarchy. We describe, in
terms of the initial data for the zero--curvature 1--form of the AKNS
hierarchy, the moduli space of these self--similar solutions in the Sato
Grassmannian. As a byproduct we characterize the points in the Segal--Wilson
Grassmannian corresponding to the Sachs rational solutions of the AKNS equation
and to the Nakamura--Hirota rational solutions of the NLS equation. An explicit
1--parameter family of Galilean self--similar solutions of the AKNS equation
and the associated solution to the NLS equation is determined.Comment: 25 pages in AMS-LaTe
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