Acute pseudogout after pamidronate infusion.

International audienceA 72-year-old man, treated with a 60-mg intravenous infusion of pamidronate for shoulder hand syndrome, developed after few hours an acute pseudogout arthritis of his right knee. Diagnosis was confirmed by synovial fluid analysis and was associated with hypocalcemia. Only a few cases are reported in the literature. The mechanism of this potential side effect remains speculative

[Locoregional polymorphous Pseudomonas aeruginosa skin infection.]

International audienceA 72-year-old diabetic woman was referred with a painful chronic leg ulcer associated with venous and arterial insufficiency. She then developed a polymorphous skin infection due to Pseudomonas aeruginosa, with ecthyma gangrenosum, subcutaneous abscess and panniculitis of the homolateral inferior limb, without general sepsis. Although P. aeruginosa infection may induce polymorphous skin lesions, they are most often observed in immunocompromised patients following septicaemia

Experience with biologics for psoriasis in daily practice: Rotational therapy is required.

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Use of interferon-alpha in two patients with Merkel cell carcinoma positive for Merkel cell polyomavirus.

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