9-(4-Nitro­phenyl­sulfon­yl)-9H-carbazole

In the title mol­ecule, C18H12N2O4S, the carbazole skeleton is nearly planar [maximum deviation = 0.037 (1) Å] and is oriented at a dihedral angle of 73.73 (5)° with respect to the benzene ring. An intra­molecular C—H⋯O hydrogen bond links a nitro O atom to the carbazole skeleton. In the crystal, inter­molecular C—H⋯O hydrogen bonds link the mol­ecules into a three-dimensional network. π–π contacts between inversion-related benzene rings [centroid–centroid distance = 3.7828 (8) Å] and two weak C—H⋯π inter­actions may also stabilize the structure

Steinert's syndrome presenting as anal incontinence: a case report

<p>Abstract</p> <p>Introduction</p> <p>Myotonic dystrophy (MD) or Steinert's syndrome is a rare cause of chronic diarrhea and anal incontinence. In the presence of chronic diarrhea and fecal incontinence with muscle weakness, neuromuscular disorders such as myotonic dystrophy should be considered in the differential diagnosis.</p> <p>Case Presentation</p> <p>We present the case of a 45-year-old Turkish man with Steinert's syndrome, who was not diagnosed until the age of 45.</p> <p>Conclusions</p> <p>In clinical practice, the persistence of diarrhea and fecal incontinence with muscle weakness should suggest that the physician perform an anal manometric study and electromyography. Neuromuscular disorders such as myotonic dystrophy should be considered in the differential diagnosis.</p

Preparation of highly thermally stable and conductive Schiff base polymer: Molecular weight monitoring and investigation of antimicrobial properties

WOS: 000430763000005A novel thermally stable polyazomethine with phenol group, Poly(4-[[4-(dimethylamino)benzylidene] amino]phenol) P(4-DBAP), was synthesized from 4-[[4-(dimethylamino)benzylidene]aminc]phenol) (4-DBAP) in aqueous alkaline medium via oxidative polycondensation with NaOCl, H2O2, and O-2 oxidants. The change of the yield and molecular weight distribution of P(4-DBAP) with oxidant type and concentration, monomer concentration, and polymerization temperature and time were analyzed. The structures of the monomer and polymer were confirmed by UV-Vis, FTIR, H-1-NMR, C-13-NMR and TGA techniques. The conductivity value of the polymer which was doped with iodine vapor for 24 h was reached 3.2 x 10(-5)S/cm and 1.1 x 10(-4) S/cm values by increasing 107 and 108 folds compared to the initial conductivity value at 20 degrees C and 60 degrees C, respectively. This conductivity value which was measured at 20 degrees C is the highest value reported in the literature for polyazomethines having phenol group in such a short time and at low temperature. Moreover, antimicrobial activity test was performed for 4-DBAP and P(4-DBAP) against Sarcina lutea, Enterobacter aerogenes, Escherichia coli, Enterococcus Feacalis, Klebsiella pneumoniae, Bacillus subtilis bacteria, and Candida albicans and Saccharomyces cerevisiae fungi. Although both monomer and polymer showed antibacterial activity, the polymer was more efficient compared to the monomer. (C) 2018 Elsevier B.V. All rights reserved.Ankara University Research Funds [13B4240008]We would like to thank Dr. Ashabil AYGAN (Kahramanmaras Sutcu Imam University, Faculty of Arts and Science, Department of Biology, Kahramanmaras, Turkey) for his help on antimicrobial tests. Moreover, we are grateful to Ankara University Research Funds for the financial support to this study (Project No. 13B4240008)