684 research outputs found

    Knowledge-based Expressive Technologies within Cloud Computing Environments

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    Presented paper describes the development of comprehensive approach for knowledge processing within e-Sceince tasks. Considering the task solving within a simulation-driven approach a set of knowledge-based procedures for task definition and composite application processing can be identified. This procedures could be supported by the use of domain-specific knowledge being formalized and used for automation purpose. Within this work the developed conceptual and technological knowledge-based toolbox for complex multidisciplinary task solv-ing support is proposed. Using CLAVIRE cloud computing environment as a core platform a set of interconnected expressive technologies were developed.Comment: Proceedings of the 8th International Conference on Intelligent Systems and Knowledge Engineering (ISKE2013). 201

    BOW SHOCK FRAGMENTATION DRIVEN BY A THERMAL INSTABILITY IN LABORATORY ASTROPHYSICS EXPERIMENTS

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    The role of radiative cooling during the evolution of a bow shock was studied in laboratory-astrophysics experiments that are scalable to bow shocks present in jets from young stellar objects. The laboratory bow shock is formed during the collision of two counter-streaming, supersonic plasma jets produced by an opposing pair of radial foil Z-pinches driven by the current pulse from the MAGPIE pulsed-power generator. The jets have different flow velocities in the laboratory frame and the experiments are driven over many times the characteristic cooling time-scale. The initially smooth bow shock rapidly develops small-scale non-uniformities over temporal and spatial scales that are consistent with a thermal instability triggered by strong radiative cooling in the shock. The growth of these perturbations eventually results in a global fragmentation of the bow shock front. The formation of a thermal instability is supported by analysis of the plasma cooling function calculated for the experimental conditions with the radiative packages ABAKO/RAPCAL.Comment: 9 pages, 5 figures, Accepted for publication in The Astrophysical Journal on 5th November 201

    Assessment of a continuous blood gas monitoring system in animals during circulatory stress

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    <p>Abstract</p> <p>Background</p> <p>The study was aimed to determine the measurement accuracy of The CDI™ blood parameter monitoring system 500 (Terumo Cardiovascular Systems Corporation, Ann Arbor MI) in the real-time continuous measurement of arterial blood gases under different cardiocirculatory stress conditions</p> <p>Methods</p> <p>Inotropic stimulation (Dobutamine 2.5 and 5 μg/kg/min), vasoconstriction (Arginine-vasopressin 4, 8 and 16 IU/h), hemorrhage (-10%, -20%, -35%, and -50% of the theoretical volemia), and volume resuscitation were induced in ten swine (57.4 ± 10.7 Kg).Intermittent blood gas assessments were carried out using a routine gas analyzer at any experimental phase and compared with values obtained at the same time settings during continuous monitoring with CDI™ 500 system. The Bland-Altman analysis was employed.</p> <p>Results</p> <p>Bias and precision for pO<sub>2 </sub>were - 0.06 kPa and 0.22 kPa, respectively (r<sup>2 </sup>= 0.96); pCO<sub>2 </sub>- 0.02 kPa and 0.15 kPa, respectively; pH -0.001 and 0.01 units, respectively ( r<sup>2 </sup>= 0.96). The analysis showed very good agreement for SO<sub>2 </sub>(bias 0.04,precision 0.33, r<sup>2 </sup>= 0.95), Base excess (bias 0.04,precision 0.28, r<sup>2 </sup>= 0.98), HCO<sub>3 </sub>(bias 0.05,precision 0.62, r<sup>2 </sup>= 0.92),hemoglobin (bias 0.02,precision 0.23, r<sup>2 </sup>= 0.96) and K<sup>+ </sup>(bias 0.02, precision 0.27, r<sup>2 </sup>= 0.93). The sensor was reliable throughout the experiment during hemodynamic variations.</p> <p>Conclusions</p> <p>Continuous blood gas analysis with the CDI™ 500 system was reliable and it might represent a new useful tool to accurately and timely monitor gas exchange in critically ill patients. Nonetheless, our findings need to be confirmed by larger studies to prove its reliability in the clinical setting.</p
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