Особенности метаболизма глутатиона при COVID-19

The article presents the results of studies on the effect of coronavirus infection on the metabolism of glutathione and sulfur-containing amino acids in patients with COVID-19. The defeat of the pulmonary system by the COVID-19 virus is accompanied by hypoxia, which provokes an increased excretion of cystine in the urine, which can cause tension in the metabolism of sulfur-containing amino acids and glutathione. The understanding of the mechanisms of influence of the COVID-19 virus on metabolic processes in the body has been expandedÎn lucrare sunt prezentate rezultatele studiilor privind influența infecției cu coronavirus asupra metabolismului glutationului și aminoacizilor ce conțin sulf la pacienții cu COVID-19. Afectarea sistemului pulmonar de către virusul COVID-19 este însoțită de hipoxie, care provoacă excreție sporită de cistină prin urină, care poate fi cauza stresului în metabolismul aminoacizilor ce conțin sulf și al glutationului. Sunt extinse mecanismele influenței virusului COVID-19 asupra proceselor metabolice din organismВ работе приведены результаты исследований по влиянию коронавирусной инфекции на метаболизм глутатиона и серосодержащих аминокислот у пациентов с COVID-19. Поражение легочной системы вирусом COVID-19 сопровождается гипоксией, которая провоцирует повышенную выведение цистина с мочой, что может служить причиной напряжения в метаболизме серосодержащих аминокислот и глутатиона. Расширены представления о механизмах влияния вируса COVID-19 на метаболические процессы в организм

Interactions in Chaotic Nanoparticles: Fluctuations in Coulomb Blockade Peak Spacings

We use random matrix models to investigate the ground state energy of electrons confined to a nanoparticle. Our expression for the energy includes the charging effect, the single-particle energies, and the residual screened interactions treated in Hartree-Fock. This model is applicable to chaotic quantum dots or nanoparticles--in these systems the single-particle statistics follows random matrix theory at energy scales less than the Thouless energy. We find the distribution of Coulomb blockade peak spacings first for a large dot in which the residual interactions can be taken constant: the spacing fluctuations are of order the mean level separation Delta. Corrections to this limit are studied using the small parameter 1/(kf L): both the residual interactions and the effect of the changing confinement on the single-particle levels produce fluctuations of order Delta/sqrt(kf L). The distributions we find are significantly more like the experimental results than the simple constant interaction model.Comment: 17 pages, 4 figures, submitted to Phys. Rev.