A Shell of Thermal X-ray Emission Associated with the Young Crab-like Remnant 3C58

Deep X-ray imaging spectroscopy of the bright pulsar wind nebula 3C58 confirms the existence of an embedded thermal X-ray shell surrounding the pulsar PSR J0205+6449. Radially resolved spectra obtained with the XMM-Newton telescope are well-characterized by a power-law model with the addition of a soft thermal emission component in varying proportions. These fits reproduce the well-studied increase in the spectral index with radius attributed to synchrotron burn-off of high energy electrons. Most interestingly, a radially resolved thermal component is shown to map out a shell-like structure ~6' in diameter. The presence of a strong emission line corresponding to the Ne IX He-like transition requires an overabundance of ~3 x [Ne/Ne(sun)] in the Raymond-Smith plasma model. The best-fit temperature kT ~ 0.23 keV is essentially independent of radius for the derived column density of N_H = (4.2 +/- 0.1)E21 per cm squared. Our result suggests that thermal shells can be obscured in the early evolution of a supernova remnant by non-thermal pulsar wind nebulae emission; the luminosity of the 3C58 shell is more than an order of magnitude below the upper limit on a similar shell in the Crab Nebula. We find the shell centroid to be offset from the pulsar location. If this neutron star has a velocity similar to that of the Crab pulsar, we derive an age of 3700 yr and a velocity vector aligned with the long axis of the PWN. The shell parameters and pulsar offset add to the accumulating evidence that 3C58 is not the remnant of the supernova of CE 1181.Comment: 7 pages, 8 figures, 2 tables, Latex emulateapj style. To appear in the Astrophysical Journa

Tools for live imaging of active Rho GTPases in Xenopus

Rho family GTPases are signaling molecules that orchestrate cytoskeletal dynamics in a variety of cellular processes. Because they effect localized changes to the cytoskeleton only in their active (GTP‐bound) conformation, the ability to monitor the active state of Rho GTPases in space and time is critical for understanding their function. Here, we summarize popular tools used for live imaging of active Rho GTPases, outlining advantages and drawbacks of these approaches. Additionally, we highlight key features of the Xenopus laevis embryo that make it well‐suited for epithelial cell biology and discuss how application of Rho activity reporters in the Xenopus laevis embryo led to the discovery of a novel phenomenon, junctional Rho flares.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/136041/1/dvg22998_am.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/136041/2/dvg22998.pd

Architectural/Environmental Handbook for Extraterrestrial Design

Handbook on environmental and space utilization criteria for design of extraterrestrial manned spacecraft and shelter

The effect of wildfires on wood-decay fungi in the Great Smoky Mountains National Park

Background: In late November and early December of 2019, wildfires occurred over portions of the Great Smoky Mountains National Park. More than 4,000 ha were affected by the wildfires. The objective of the research reported herein was to access the impact of these wildfires on the assemblages of wood-decay fungi associated with the study areas in the park.Methods: The investigated fungi were confined to two study areas; the first subjected to a relatively high intensity burn and the second subjected to a relatively low intensity burn. In addition to specimens of fungi obtained in the field, small pieces of coarse woody debris were assembled, brought back to the laboratory and placed in plastic chambers for incubation and kept moist. Over the course of two months, fruiting bodies appearing in these incubation chambers were observed and collected. All specimens from both the field and incubation chambers were identified from sequences of the internal transcribed spacer (ITS) region of the ribosomal DNA.Results: A total of 31 different taxa were identified along with nine taxa reported previously as unknown and uncultured. However, almost all of these records were from the study area subjected to the relatively low intensity burn.Conclusion: The relatively high intensity burn site was almost completely devoid of wood-decay fungi.Keywords: Great Smoky Mountains National Park; ITS ribosomal DNA region; Wood-decay fung

Population-Specific Vital Rate Contributions Influence Management of an Endangered Ungulate

To develop effective management strategies for the recovery of threatened and endangered species, it is critical to identify those vital rates (survival and reproductive parameters) responsible for poor population performance and those whose increase will most efficiently change a population\u27s trajectory. In actual application, however, approaches identifying key vital rates are often limited by inadequate demographic data, by unrealistic assumptions of asymptotic population dynamics, and of equal, infinitesimal changes in mean vital rates. We evaluated the consequences of these limitations in an analysis of vital rates most important in the dynamics of federally endangered Sierra Nevada bighorn sheep (Ovis canadensis sierrae). Based on data collected from 1980 to 2007, we estimated vital rates in three isolated populations, accounting for sampling error, variance, and covariance. We used analytical sensitivity analysis, life-stage simulation analysis, and a novel non-asymptotic simulation approach to (1) identify vital rates that should be targeted for subspecies recovery; (2) assess vital rate patterns of endangered bighorn sheep relative to other ungulate populations; (3) evaluate the performance of asymptotic vs. non-asymptotic models for meeting short-term management objectives; and (4) simulate management scenarios for boosting bighorn sheep population growth rates. We found wide spatial and temporal variation in bighorn sheep vital rates, causing rates to vary in their importance to different populations. As a result, Sierra Nevada bighorn sheep exhibited population-specific dynamics that did not follow theoretical expectations or those observed in other ungulates. Our study suggests that vital rate inferences from large, increasing, or healthy populations may not be applicable to those that are small, declining, or endangered. We also found that, while asymptotic approaches were generally applicable to bighorn sheep conservation planning, our non-asymptotic population models yielded unexpected results of importance to managers. Finally, extreme differences in the dynamics of individual bighorn sheep populations imply that effective management strategies for endangered species recovery may often need to be population-specific

Neutron Resonance Spectroscopy of 106Pd, and 108Pd from 20–2000 eV

Parity nonconserving asymmetries have been measured in p-wave resonances of 106Pd and 108Pd. The data analysis requires knowledge of the neutron resonance parameters. Transmission and capture γ-ray yields were measured for En=20–2000 eV with the time-of-flight method at the Los Alamos Neutron Science Center (LANSCE). A total of 28 resonances in 106Pd and 32 resonances in 108Pd were studied. The resonance parameters for 106Pd are new for all except one resonance. In 108Pd six new resonances were observed and the precision improved for many of the resonance parameters. A Bayesian analysis was used to assign orbital angular momentum for the resonances studied

A Model for the Analysis of Caries Occurrence in Primary Molar Tooth Surfaces

Recently methods of caries quantification in the primary dentition have moved away from summary ‘whole mouth’ measures at the individual level to methods based on generalised linear modelling (GLM) approaches or survival analysis approaches. However, GLM approaches based on logistic transformation fail to take into account the time-dependent process of tooth/surface survival to caries. There may also be practical difficulties associated with casting parametric survival-based approaches in a complex multilevel hierarchy and the selection of an optimal survival distribution, while non-parametric survival methods are not generally suitable for the assessment of supplementary information recorded on study participants. In the current investigation, a hybrid semi-parametric approach comprising elements of survival-based and GLM methodologies suitable for modelling of caries occurrence within fixed time periods is assessed, using an illustrative multilevel data set of caries occurrence in primary molars from a cohort study, with clustering of data assumed to occur at surface and tooth levels. Inferences of parameter significance were found to be consistent with previous parametric survival-based analyses of the same data set, with gender, socio-economic status, fluoridation status, tooth location, surface type and fluoridation status-surface type interaction significantly associated with caries occurrence. The appropriateness of the hierarchical structure facilitated by the hybrid approach was also confirmed. Hence the hybrid approach is proposed as a more appropriate alternative to primary caries modelling than non-parametric survival methods or other GLM-based models, and as a practical alternative to more rigorous survival-based methods unlikely to be fully accessible to most researchers