How often are clinicians performing genital exams in children with disorders of sex development?

Background: We sought to determine the frequency with which genital exams (GEs) are performed in children with disorders of sex development (DSD) and ambiguous genitalia (AG) during routine visits to the pediatric endocrine clinic. Methods: Medical records of children with DSD and AG seen at one large academic center since 2007 were reviewed. Data analyzed included diagnosis, sex of rearing, age, initial or follow up visit, number of individuals present and sex of the pediatric endocrinologist. Repeated measures analysis was performed to evaluate associations between GEs and patient/physician factors. Results: Eighty-two children with DSD and AG who had a total of 632 visits were identified. Sex of rearing was female in 78% and the most common diagnosis was congenital adrenal hyperplasia (CAH) (68%). GEs were performed in 35.6% of visits. GEs were more likely in patients with male sex of rearing (odds ratio [OR] 17.81, p=0.006), during initial vs. follow-up visits (OR 5.99, p=0.012), and when the examining endocrinologist was female (OR 3.71, p=0.014). As patients aged, GEs were less likely (OR 0.76, p<0.0001). Conclusions: GEs were performed in approximately one-third of clinic visits in children with DSD and AG. Male sex of rearing, initial visits and female pediatric endocrinologist were associated with more frequent GEs

Modulated rotating waves in the magnetized spherical Couette system

We present a study devoted to a detailed description of modulated rotating waves (MRW) in the magnetized spherical Couette system. The set-up consists of a liquid metal confined between two differentially rotating spheres and subjected to an axially applied magnetic field. When the magnetic field strength is varied, several branches of MRW are obtained by means of three dimensional direct numerical simulations (DNS). The MRW originate from parent branches of rotating waves (RW) and are classified according to Rand's (Arch. Ration. Mech. Anal 79:1-37, 182) and Coughling & Marcus (J. Fluid Mech. 234:1-18,1992) theoretical description. We have found relatively large intervals of multistability of MRW at low magnetic field, corresponding to the radial jet instability known from previous studies. However, at larger magnetic field, corresponding to the return flow regime, the stability intervals of MRW are very narrow and thus they are unlikely to be found without detailed knowledge of their bifurcation point. A careful analysis of the spatio-temporal symmetries of the most energetic modes involved in the different classes of MRW will allow in the future a comparison with the HEDGEHOG experiment, a magnetized spherical Couette device hosted at the Helmholtz-Zentrum Dresden-Rossendorf.Comment: Contains 3 tables and 8 figures. Published in the Journal of Nonlinear Scienc

Magnetic Field Saturation in the Riga Dynamo Experiment

After the dynamo experiment in November 1999 had shown magnetic field self-excitation in a spiraling liquid metal flow, in a second series of experiments emphasis was placed on the magnetic field saturation regime as the next principal step in the dynamo process. The dependence of the strength of the magnetic field on the rotation rate is studied. Various features of the saturated magnetic field are outlined and possible saturation mechanisms are discussed.Comment: 4 pages, 8 figure

The effect of television on the leisure time activities of sixth grade children in Medford, Massachusetts.

Thesis (Ed.M.)--Boston Universit

Contactless inductive flow tomography

The three-dimensional velocity field of a propeller driven liquid metal flow is reconstructed by a contactless inductive flow tomography (CIFT). The underlying theory is presented within the framework of an integral equation system that governs the magnetic field distribution in a moving electrically conducting fluid. For small magnetic Reynolds numbers this integral equation system can be cast into a linear inverse problem for the determination of the velocity field from externally measured magnetic fields. A robust reconstruction of the large scale velocity field is already achieved by applying the external magnetic field alternately in two orthogonal directions and measuring the corresponding sets of induced magnetic fields. Kelvin's theorem is exploited to regularize the resulting velocity field by using the kinetic energy of the flow as a regularizing functional. The results of the new technique are shown to be in satisfactory agreement with ultrasonic measurements.Comment: 9 Figures; to appear in Phys. Rev

Triadic resonances in non-linear simulations of a fluid flow in a precessing cylinder

We present results from three-dimensional non-linear hydrodynamic simulations of a precession driven flow in cylindrical geometry. The simulations are motivated by a dynamo experiment currently under development at Helmholtz-Zentrum Dresden-Rossendorf (HZDR) in which the possibility of generating a magnetohydrodynamic dynamo will be investigated in a cylinder filled with liquid sodium and simultaneously rotating around two axes. In this study, we focus on the emergence of non-axisymmetric time-dependent flow structures in terms of inertial waves which - in cylindrical geometry - form so-called Kelvin modes. For a precession ratio ${\rm{Po}}=\Omega_p/\Omega_c=0.014$ the amplitude of the forced Kelvin mode reaches up to one fourth of the rotation velocity of the cylindrical container confirming that precession provides a rather efficient flow driving mechanism even at moderate values of ${\rm{Po}}$. More relevant for dynamo action might be free Kelvin modes with higher azimuthal wave number. These free Kelvin modes are triggered by non-linear interactions and may constitute a triadic resonance with the fundamental forced mode when the height of the container matches their axial wave lengths. Our simulations reveal triadic resonances at aspect ratios close to those predicted by the linear theory except around the primary resonance of the forced mode. In that regime we still identify various free Kelvin modes, however, all of them exhibit a retrograde drift around the symmetry axis of the cylinder and none of them can be assigned to a triadic resonance. The amplitudes of the free Kelvin modes always remain below the forced mode but may reach up to 6% of the of the container's angular velocity. The properties of the free Kelvin modes will be used in future simulations of the magnetic induction equation to investigate their ability to provide for dynamo action.Comment: 26 pages, 14 figures, submitted to New J. Phy

Role of soft-iron impellers on the mode selection in the VKS dynamo experiment

A crucial point for the understanding of the von-K\'arm\'an-Sodium (VKS) dynamo experiment is the influence of soft-iron impellers. We present numerical simulations of a VKS-like dynamo with a localized permeability distribution that resembles the shape of the flow driving impellers. It is shown that the presence of soft-iron material essentially determines the dynamo process in the VKS experiment. % An axisymmetric magnetic field mode can be explained by the combined action of the soft-iron disk and a rather small $\alpha$-effect parametrizing the induction effects of unresolved small scale flow fluctuations