Critical success factors of web-based supply-chain management systems : an exploratory study

Author name used in this publication: E. W. T. NgaiAuthor name used in this publication: T. C. E. Cheng2004-2005 > Academic research: refereed > Publication in refereed journalAccepted ManuscriptPublishe

The Effect of Vestibular Stimulation on Eye-Hand Coordination and Postural Control in Elite Basketball Players

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Role of epac in the pathogenesis of ischemic stroke

Poster Presentations: Theme 2published_or_final_version15th Research Postgraduate Symposium, Hong Kong, China, 1-2 December 2010. In Abstract - Poste Presentations (Theme II) of 15th Research Postgraduate Symposium, 2010, p. 8

Single-channel electroencephalographic recording in children with developmental coordination disorder: Validity and influence of eye blink artifacts

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Would transcranial direct current stimulation (tDCS) enhance the effects of working memory training in older adults with mild neurocognitive disorder due to Alzheimer’s disease: study protocol for a randomized controlled trial

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Performance of large-size superconducting coil in 0.21T MRI system

A high-temperature superconductor (HTS) was used on magnetic resonance imaging (MRI) receiver coils to improve image quality because of its intrinsic low electrical resistivity [1], [2]. Typical HTS coils are surface coils made of HTS thin-film wafers. Their applications are severely limited by the field of view (FOV) of the surface coil configuration, and the improvement in image quality by HTS coil is also reduced as the ratio of sample noise to coil noise increases. Therefore, previous HTS coils are usually used to image small in vitro samples, small animals, or peripheral human anatomies [3]-[5]. We used large-size HTS coils (2.5-, 3.5-, and 5.5-in mean diameter) to enhance the FOV and we evaluated their performance through phantom and human MR images. Comparisons were made among HTS surface coils, copper surface coils, and cool copper surface coils in terms of the signal-to-noise ratio (SNR) and sensitivity profile of the images. A theoretical model prediction was also used to compare against the experimental result. We then selected several human body parts, including the wrist, feet, and head, to illustrate the advantage of HTS coil over copper coil when used in human imaging. The results show an SNR gain of 200% for 5.5-in HTS coil versus same size copper coils, while for 2.5- and 3.5-in coils it is 250%. We also address the various factors that affect the performance of large size HTS coils, including the coil-to-sample spacing due to cryogenic probe and the coil-loading effect.published_or_final_versio

Effects of Ving Tsun Chinese martial art training on upper extremity muscle strength and eye-hand coordination in community-dwelling middle-aged and older adults: A pilot study

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Suicide in Hong Kong: A case-control psychological autopsy study

Background. The relative contribution of psychosocial and clinical risk factors to suicide among Chinese populations is an important issue. In Hong Kong, this issue requires vigorous examination in light of a 50% increase in suicide rate between 1997 and 2003. Method. Using a case-control psychological autopsy method, 150 suicide deceased were compared with 150 living controls matched by age and gender. Semi-structured interviews were conducted with the next-of-kin of the subjects. Data were collected on a wide range of potential risk and protective factors, including demographic, life event, clinical and psychological variables. The relative contribution of these factors towards suicide was examined in a multiple logistic regression model. Results. Six factors were found to significantly and independently contribute to suicide: unemployment, indebtedness, being single, social support, psychiatric illness, and history of past attempts. Conclusions. Both psychosocial and clinical factors are important in suicides in Hong Kong. They seem to have mediated suicide risk independently. In addition, socio-economic adversities seem to have played a relatively important role in the increasing suicide rate in Hong Kong. © 2006 Cambridge University Press.published_or_final_versio

EPAC2-deficiency leads to more severe neurological deficit and larger infarct with higher glial reactivity after transient middle cerebral occlusion

Abstract no. 912INTRODUCTION: Exchange proteins activated by cAMP (Epac1 and Epac2) belong to a family of cAMP-regulated guanine nucleotide exchange factors (cAMPGEFs) for the small GTPases, Rap1 and Rap2[1]. Epac1 was thought to be important in maintenance of tight and adhesion junctions between endothelial cells[2] , suggesting that Epac may play an important role in blood brain barrier (BBB) function. OBJECTIVE: Previously, it was shown that Epac2 mRNA is expressed in the brain[3]. Here, the protein expression of Epac2 was determined and compared to that of Epac1. In addition, the role of Epac2 was determined in the BBB and brain function after ischemia/reperfusion injury. METHOD: Six regions of brain from Epac2 wild type (Epac2+/+) mice was dissected, and proteins were extracted in order to determine the expression of Epac1 and Epac2 under normal and …postprintThe 25th International Symosium on Cerebral Blood Flow, Metabolism, and Function & 10th International Conference on Quantification of Brain Function with PET (BRAIN’11 & BRAINPET’11 ), Barcelona, Spain, 25-28 May 2011

Transdermal delivery of propranolol hydrochloride through chitosan nanoparticles dispersed in mucoadhesive gel

This study aimed at improving the systemic bioavailability of propranolol-HCl by the design of transdermal drug delivery system based on chitosan nanoparticles dispersed into gels. Chitosan nanoparticles were prepared by ionic gelation technique using tripolyphosphate (TPP) as a cross-linking agent. Characterization of the nanoparticles was focused on particle size, zeta potential, surface texture and morphology, and drug encapsulation efficiency. The prepared freeze dried chitosan nanoparticles were dispersed into gels made of poloxamer and carbopol and the rheological behaviour and the adhesiveness of the gels were investigated. The results showed that smallest propranolol loaded chitosan nanoparticles were achieved with 0.2% chitosan and 0.05% TPP. Nanoparticles were stable in suspension with a zeta potential (ZP) above ±30 mV to prevent aggregation of the colloid. Zeta potential was found to increase with increasing chitosan concentration due to its cationic nature. At least 70% of entrapment efficiency and drug loading were achieved for all prepared nanoparticles. When chitosan nanoparticles dispersed into gel consisting of poloxamer and carbopol, the resultant formulation exhibited thixotropic behaviour with a prolonged drug release properties as shown by the permeation studies through pig ear skin. Our study demonstrated that the designed nanoparticles-gel transdermal delivery system has a potential to improve the systemic bioavailability and the therapeutic efficacy of propranolol-HCl