Analyzing the Impact of Corporate Governance Practices and Disclosures on the Financial Performance of the Textile Industry in India

Corporations in modern day practice have been regulated by both the regulator and shareholders on how well the company is governed. Fall of companies like WorldCom, Enron and Satyam have raised the issue of corporate governance practiced followed by corporations the world over. In the Indian context with the rise in corporate scandals, SEBI has been regulating the operations of corporations and have introduced Clause 49 Listing Agreement and every Indian public listed company needs to comply with the same. On the other hand there are certain voluntary disclosures which the corporations can make on their own will to gain shareholder confidence and trust. This thesis would present a study on the impact of corporate governance practices and disclosures on the financial value of the textile industry in India. The paper would study the corporate governance factors like board size, independent directors and number of disclosures which have an impact on the financial value of the measured which would be measured by Return on Assets, Return on Equity and Earnings per Share. The thesis would be studied over a period of four years from 2005-06 to 2008-09. The research has been based on secondary information from reliable sources which would provide accurate findings. Overall the research focuses on concluding whether corporate governance practices have a positive impact or a negative impact on the financial value of textile firms in India

Transdermal Delivery of Antihypertensive Agents: A tabular update

Transdermal Drug Delivery System is viable drug delivery platform technology and has a strong market world wide. Transdermal Drug Delivery System is particularly desirable for drugs that need prolonged administration at controlled plasma level that basis make appropriateness to antihypertensive agents for their transdermal development. Controlled zero order absorption, easily termination of drug delivery, easy to administration also support for popularity of transdermal delivery. This paper reviews the work on transdermal studies of antihypertensive agents in the tabular form.Keywords: Transdermal, Antihypertensive agents

Causal ambiguity: deciphering the etiology of secondary thrombotic microangiopathy with systemic lupus erythematosus and vivax malaria

Hemolytic uremic syndrome (HUS) falls under the spectrum of thrombotic microangiopathy (TMA) characterized by microangiopathic hemolytic anemia, thrombocytopenia, and thrombi in small vessels leading to end-organ damage. It's classified into typical HUS (caused by Shiga toxin-producing E. coli), atypical HUS (due to uncontrolled complement activation), and secondary HUS (sHUS) linked with coexisting conditions. We present a compelling case of a 21-year-old female with fever, jaundice, anemia, thrombocytopenia, and oliguric acute kidney injury (AKI), ultimately diagnosed with Plasmodium vivax malaria. Despite adequate antimalarial therapy, the patient's clinical trajectory remained intricate, characterized by sustained hematological abnormalities and renal dysfunction. A comprehensive assessment revealed Coombs-negative hemolytic anemia. Subsequently, a renal biopsy confirmed TMA. Considering the rarity of vivax malaria causing TMA, an autoimmune workup was conducted, suggesting systemic lupus erythematosus (SLE). Systemic autoimmune disease-associated HUS (SAID-HUS) is a rare entity that exhibits diverse clinical presentations, with SLE being best-described etiology in literature. SLE-associated HUS was considered and was managed with steroids and hydroxychloroquine resulting in significant renal and hematological improvement. This report underscores significance of assessing autoimmune factors in case of secondary TMA, while also shedding light on evolving understanding of vivax malaria's potential relationship with TMA

Energy Audit-A Case Study

Abstract -Energy audit is a process of checking the way energy is used and identify areas where wastage can be minimize if not totally eradicate. Energy audit consists of several tasks which can be carried out depending on the type of audit and the function of audited facility. It started with review the historical data of energy consumption which can be compiled from the electricity bills. These data is important in order to understand the patterns of energy used and their trend. After obtaining the information on energyconsumption, the next step is to set up an energy audit program. This program shou ld start with site survey in order to obtain information on present energy used.The energy utilization such as running hours of air-conditioning, lighting levels, locations of unnecessary air-conditioning and lighting due to unoccupied areas, temperature and humidity, chillers/pump scheduling and setting, efficiencies of equipment's and machine and the areas of high energy consumption and the possibility to reduce consumption should be record for further analysis.The energy audit discussed in this paper will only focused in the RGPV library building and university of teaching department. It is carried out in aim of analysing and identifying possible energy saving measures in the library, which can later be implem ented for energy efficiency program in RGPV

Outcomes of Sphincter of Oddi Manometry When Performed in Low Volumes

Background. Sphincter of Oddi manometry is a highly specialized procedure associated with an increased risk of procedural complications. Published studies have typically been performed in large volume manometry centers. Objective. To examine the outcomes and complication rate of SOM when performed in small volumes. Design. Retrospective analysis at a tertiary care referral hospital that infrequently performs Sphincter of Oddi manometry. Patient records were reviewed for procedural details, patient outcomes, and complications after sphincter of Oddi manometry. Results. 36 patients, 23 (23 type II sphincter of Oddi dysfunction (SOD), 13 type III SOD) underwent sphincter of Oddi manometry and were followed up for mean of 16 months. Nine Type II patients (90%) with elevated basal sphincter pressures noted symptom improvement after sphincterotomy compared with only 3 patients (43%) of the patients with normal basal pressures. In type III SOD, 7 patients had elevated basal SO pressure and underwent sphincterotomy. Three patients (43%) improved. There were six (16%) procedure-related complications. There were four cases of post ERCP pancreatitis (11%), all of which were mild. Conclusion. In low numbers, sphincter of Oddi manometry can be performed successfully and safely by experienced biliary endoscopists with results that are comparable to large volume centers

Pruning in guava (Psidium guajava) and appraisal of consequent flowering phenology using modified BBCH scale

The guava (Psidium guajava L.) shows well defined phenological stages during growth, flowering and fruiting stages depending upon climatic conditions which of course is amenable to manipulations through cultural interventions. The BBCH scale (Biologische Bundesantalt Bundessortenant and Chemiscle Industrie) is used for recording the data of the different phenological stages in coded form starting from bud development, vegetative stages, floral stages and ends in fruit maturity. Pruning is an important tool for increasing the production but it impacts the normal phenological stages by causing variation in the occurrence of principal and secondary stages. Therefore, the normal BBCH scale proves to be erroneous. In order to assess the quantum of variation on the normal phenology, an experiment was carried out in the guava cv. Lalit for collection of phenological data using the traditional nomenclature described by Fleckinger (1945) and to relate them to the BBCH general scale in pruned or unpruned trees. Significant variation in the principal growth stages was observed as a result of pruning during February, May and September. The duration between the pruning and the beginning bud sprout was from 11 to 15 days during different times of pruning. In contrast, the control unpruned tree showed bud emergence within 2-3 days. The flowering in February and September pruned trees ranged from 78 to 93 days from flower opening and took 153 and 150 days, respectively, for the fruit ripeness as compared to control (129-146 days). Interestingly, beginning of bud sprout occurred in 7 days in May pruning as compared to 3 days in control and the 50 % flowering was hastened and occurred in 43 days and fruit ripening took 136 days. Thus the normal BBCH scale proved to be erroneous in trees subjected to pruning. Phenology of guava according to the traditional Fleckinger Code and the aberrations in the BBCH General Scale resulting from pruning is described in this paper

Preparation and characterization of gellan-chitosan polyelectrolyte complex beads

The purpose of the present investigation was to prepare gellan-chitosan polyelectrolyte complex beads in one step and to explore the potential of the prepared beads in the oral delivery of metronidazole (log P = 0.0) and metronidazole benzoate (log P = 2.19). Beads were prepared by extruding aqueous solution of gellan gum (with or without drugs) into chitosan solution in acetic acid pH adjusted to 3.5. Prepared beads exhibited poor encapsulation and burst release for metronidazole, while very high encapsulation and extended release was observed for metronidazole benzoate in simulated gastric fluid (SGF, pH 1.2). Incorporation of type A & B gelatin significantly improved the metronidazole encapsulation in the beads but the release pattern remained the same. Overall, gellan-chitosan beads showed poor retardant capacity of drug release for metronidazole whereas good retardant capacity was observed for metronidazole benzoate.Colegio de Farmacéuticos de la Provincia de Buenos Aire

Genomic characterization and epidemiology of an emerging SARS-CoV-2 variant in Delhi, India

Delhi, the national capital of India, experienced multiple severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreaks in 2020 and reached population seropositivity of >50% by 2021. During April 2021, the city became overwhelmed by COVID-19 cases and fatalities, as a new variant, B.1.617.2 (Delta), replaced B.1.1.7 (Alpha). A Bayesian model explains the growth advantage of Delta through a combination of increased transmissibility and reduced sensitivity to immune responses generated against earlier variants (median estimates: 1.5-fold greater transmissibility and 20% reduction in sensitivity). Seropositivity of an employee and family cohort increased from 42% to 87.5% between March and July 2021, with 27% reinfections, as judged by increased antibody concentration after a previous decline. The likely high transmissibility and partial evasion of immunity by the Delta variant contributed to an overwhelming surge in Delhi

SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion

Abstract: The B.1.617.2 (Delta) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first identified in the state of Maharashtra in late 2020 and spread throughout India, outcompeting pre-existing lineages including B.1.617.1 (Kappa) and B.1.1.7 (Alpha)1. In vitro, B.1.617.2 is sixfold less sensitive to serum neutralizing antibodies from recovered individuals, and eightfold less sensitive to vaccine-elicited antibodies, compared with wild-type Wuhan-1 bearing D614G. Serum neutralizing titres against B.1.617.2 were lower in ChAdOx1 vaccinees than in BNT162b2 vaccinees. B.1.617.2 spike pseudotyped viruses exhibited compromised sensitivity to monoclonal antibodies to the receptor-binding domain and the amino-terminal domain. B.1.617.2 demonstrated higher replication efficiency than B.1.1.7 in both airway organoid and human airway epithelial systems, associated with B.1.617.2 spike being in a predominantly cleaved state compared with B.1.1.7 spike. The B.1.617.2 spike protein was able to mediate highly efficient syncytium formation that was less sensitive to inhibition by neutralizing antibody, compared with that of wild-type spike. We also observed that B.1.617.2 had higher replication and spike-mediated entry than B.1.617.1, potentially explaining the B.1.617.2 dominance. In an analysis of more than 130 SARS-CoV-2-infected health care workers across three centres in India during a period of mixed lineage circulation, we observed reduced ChAdOx1 vaccine effectiveness against B.1.617.2 relative to non-B.1.617.2, with the caveat of possible residual confounding. Compromised vaccine efficacy against the highly fit and immune-evasive B.1.617.2 Delta variant warrants continued infection control measures in the post-vaccination era