Full Length Research Paper Lack of correlation between H2O2 production and in vitro anti-staphyloccocal activity of vaginal Lactobacillus spp.

Lactobacilli are considered to play important roles in human health as they are known to secrete inhibitory substances to prevent infection by pathogenic organisms. Previously we have isolated 77 strains of Lactobacillus spp. from human vaginas. In this study, using the plate diffusion method, strains showing in vitro antagonistic activity against pathogenic Staphylococcus aureus were screened. Because Lactobacillus spp. are known to produce hydrogen peroxide (H2O2) as an antimicrobialsubstance, we attempted to determine if there is a consistent link between in vitro anti-staphylococcal activity and H2O2 production by Lactobacillus spp. A simple quantitative analysis of H2O2 produced by Lactobacillus spp. was performed by a modified spectrophotometric method. A statistically significant correlation was not found between in vitro anti-staphylococcal activity and H2O2 production

Strategic Implications of the Open-Market Paradigm Under Digital Convergence: The Case of Small Business C2C

This article presents the open-market paradigm in the context of digital convergence and proposes strategic directions for open-market participants. Although not a new phenomenon, open market has become the most popular e-business model, linking millions of buyer and seller individuals (Customer to Customer: C2C). This article examines the drivers of digital convergence that enable the open-market paradigm and conducts industry and Blue Ocean analyses for open-market business. Finally, a real-world application – the Cyworld market of Korea – is presented as an illustrative example

Application of a paste-type acellular dermal matrix for coverage of chronic ulcerative wounds

Background Chronic wounds occur due to failure of the normal healing process, associated with a lack of deposition of cellular components and a suitable microenvironment such as the extracellular matrix (ECM). Acellular dermal matrix (ADM) is viewed as an ECM substitute, and a paste-type ADM has recently been introduced. We hypothesized that CGPaste, an injectable paste-type ADM, could serve as a scaffold and promote wound healing. Methods We retrospectively studied seven patients in whom CGPaste was applied between 2017 and 2018, who had pressure ulcers, necrotizing fasciitis, diabetic foot ulcers, traumatic defects, and osteomyelitis. The goal of applying CGPaste was to achieve complete wound healing with re-epithelialization or growth of granulation tissue, depending upon the wound bed status. CGPaste was injected based on the wound size along with the application of a dressing. Results Four of the seven patients showed granulation tissue on their wound bed, while the other three patients had a bony wound bed. The mean wound area was 453.57 mm2 and the depth was 10.71 mm. Wound healing occurred in five of the seven patients (71.43%). The mean duration of complete healing was 2.4 weeks. Two patients showed failure due to paste absorption (29.57%); these patients had wound beds comprising bone with relatively large and deep wounds (40×30 and 30×20 mm2 in area and 15 and 10 mm in depth). Conclusions CGPaste is an effective option for coverage of small and deep chronic wounds for which a flap operation or skin grafting is unfeasible

Comparison of Stemness and Gene Expression between Gingiva and Dental Follicles in Children

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Comparison of volume-controlled and pressure-controlled ventilation using a laryngeal mask airway during gynecological laparoscopy

Background: Several publications have reported the successful, safe use of Laryngeal Mask Airway (LMA)-Classic devices in patients undergoing laparoscopic surgery. However, there have been no studies that have examined the application of volume-controlled ventilation (VCV) or pressure-controlled ventilation (PCV) using a LMA during gynecological laparoscopy. The aim of this study is to compare how the VCV and PCV modes and using a LMA affect the pulmonary mechanics, the gas exchange and the cardiovascular responses in patients who are undergoing gynecological laparoscopy. Methods: Sixty female patients were randomly allocated to one of two groups, (the VCV or PCV groups). In the VCV group, baseline ventilation of the lung was performed with volume-controlled ventilation and a tidal volume of 10 ml/kg ideal body weight (IBW). In the PCV group, baseline ventilation of the lung using pressure-controlled ventilation was initiated with a peak airway pressure that provided a tidal volume of 10 ml/kg IBW and an upper limit of 35 cmH2O. The end-tidal CO2, the peak airway pressures (Ppeak), the compliance, the airway resistance and the arterial oxygen saturation were recorded at T1: 5 minutes after insertion of the laryngeal airway, and at T2 and T3: 5 and 15 minutes, respectively, after CO2 insufflation. Results: The Ppeak at 5 minutes and 15 minutes after CO2 insufflation were significantly increased compared to the baseline values in both groups. Also, at 5 minutes and 15 minutes after CO2 insufflation, there were significant differences of the Ppeak between the two groups. The compliance decreased in both groups after creating the pneumopertoneim (P < 0.05). Conclusions: Our results demonstrate that PCV may be an effective method of ventilation during gynecological laparoscopy, and it ensures oxygenation while minimizing the increases of the peak airway pressure after CO2 insufflation. ��� the Korean Society of Anesthesiologists, 2011

Sketch-based Video Object Localization

We introduce Sketch-based Video Object Localization (SVOL), a new task aimed at localizing spatio-temporal object boxes in video queried by the input sketch. We first outline the challenges in the SVOL task and build the Sketch-Video Attention Network (SVANet) with the following design principles: (i) to consider temporal information of video and bridge the domain gap between sketch and video; (ii) to accurately identify and localize multiple objects simultaneously; (iii) to handle various styles of sketches; (iv) to be classification-free. In particular, SVANet is equipped with a Cross-modal Transformer that models the interaction between learnable object tokens, query sketch, and video through attention operations, and learns upon a per-frame set matching strategy that enables frame-wise prediction while utilizing global video context. We evaluate SVANet on a newly curated SVOL dataset. By design, SVANet successfully learns the mapping between the query sketches and video objects, achieving state-of-the-art results on the SVOL benchmark. We further confirm the effectiveness of SVANet via extensive ablation studies and visualizations. Lastly, we demonstrate its transfer capability on unseen datasets and novel categories, suggesting its high scalability in real-world application

Should I Stay or Should I Go: The Impact of Public Duty Motivation on Turnover Intentions

Despite the expansion of public service motivation (PSM) research in recent years, only a few studies have linked PSM with public employees turnover, and they have typically understood turnover as a dichotomous decision of staying versus leaving. Unlike previous research, we explore the relationship by taking into account various exit options. Utilizing data from the 2005 Merit Principles Survey, we classify public employees exit strategies into four types—not leaving, retiring, moving to another federal agency, and resigning from federal service—and examine how an indirect measure of PSM influences which of these exit strategies they intend to follow. We employ the indirect measure due to data vailability; following previous research, we name this measure public duty motivation. Our findings suggest that the impact of public duty motivation varies across intended exit strategies: it decreases the likelihood of public employees intending to retire, while it leads them to be more likely to intend to move to another job within the federal government. In contrast, it is not a significant predictor of public employees intention to resign from federal service