an experience of urban transformation in multan pakistani punjab

This publication concerns studies, programmes and designs for the project Sustainable Social Economic and Environmental Revitalization in the historic core of Multan City in Pakistani Punjab developed by several Politecnico di Milano Departments and Fondazione Politecnico di Milano, an institution that cooperates with Politecnico di Milano in the research fields of architecture, engineering and industrial design. The activities are part of the Debt Swap Agreement signed in 2006 between the governments of Italy and Pakistan for development in the social sectors. Besides the extraordinarily valuable architecture of the Walled City of Multan and its dense and hard-working population, there is a physical and environmental condition that is extremely problematic and that may threaten the continuity of life in the historic part of a city, well known for being among the world's most ancient settlements. The social and cultural interest and the academic challenge of a new opportunity to deal with great traditions pushed the researchers to face the urgency and delicacy of a very complex theme. After the analysis, the surveys and the proposals, the Politecnico group completed the first operational phase reorganizing one of the main City Gate Place, building a new open pavilion and restoring a huge public building and the Gate. The last activity, planned and not yet implemented, refers to the Sarafa Bazaar Project, an integrated system for the urban arrangement through infrastructures systems as sewerage, public lighting and shading, new paving and conservation of historic building's facades

A Randomised Experiment Evaluating the Mindful Raisin Practice as a Method of Reducing Chocolate Consumption During and After a Mindless Activity

The present study investigated the impact of the mindful raisin exercise on overeating during and after the experiment while controlling for wellbeing. One-hundred and twenty-eight participants were recruited and completed a questionnaire on wellbeing (i.e. depression, anxiety and stress) and state mindfulness. Participants were randomly allocated to either the mindful raisin exercise or a newspaper reading control condition. The State Mindfulness Scale was then completed again, and participants watched a neutral video while exposed to chocolate for 10 min. For those 10 min, results showed that the mindfulness condition translated into lower food consumption during the mindless activity when compared to the control condition. Post experiment, participants were asked to wait for 5 min, and any extra chocolate consumption during this time was recorded. Post-consumption was non-significantly different between the two groups, with those in the mindfulness condition consuming 1.3 g less than those in the control group. Controlling for wellbeing did not alter the impact of the mindfulness intervention on consumption. Implications for future work and practical applications for weight regulation are discussed

Germline selection shapes human mitochondrial DNA diversity.

Approximately 2.4% of the human mitochondrial DNA (mtDNA) genome exhibits common homoplasmic genetic variation. We analyzed 12,975 whole-genome sequences to show that 45.1% of individuals from 1526 mother-offspring pairs harbor a mixed population of mtDNA (heteroplasmy), but the propensity for maternal transmission differs across the mitochondrial genome. Over one generation, we observed selection both for and against variants in specific genomic regions; known variants were more likely to be transmitted than previously unknown variants. However, new heteroplasmies were more likely to match the nuclear genetic ancestry as opposed to the ancestry of the mitochondrial genome on which the mutations occurred, validating our findings in 40,325 individuals. Thus, human mtDNA at the population level is shaped by selective forces within the female germ line under nuclear genetic control, which ensures consistency between the two independent genetic lineages.NIHR, Wellcome Trust, MRC, Genomics Englan

Wing And Fin Load Characteristics Of 1/15 Scale Lca Sge 26d Flow Through Model Tested At 8' X 8' Transonic Pd Ea 9211 Wind-Tunnel, Calspan U .S .A .

Experimental Study Has Been Made On The 1/15 Scale LCA SGE26D Model In The 8' X 8' CALSPAN Transonic Wind Tunnel USA To Determine Normal Load Characteristics Of Metric Wing And Fin At Mach Numbers Of 0 .5-To 1 .3 In The Angle Of Attack And Angle Of Side Slip Range Of -5 To 35 Deg And -10 To 10 Deg Respectively. Effects Of Deployment Of Leading Edge Slat, Deflection Of Elevons, Rudders And Installation Of Medium Range Missiles On These Characteristics Were Studied. A New Calibration Method Which Reduces The Systematic Errors By A Factor Of 20 Over The Traditional Global Linear Least Square Method (Used To Fit Calibration Data) Has Been Employed'for The Evaluation Of Normal Load. The Result Show That The Wing Load Sharing Varies From 64% At Subsonic Speeds To About 70% At Transonic Speeds. Further The Deployment Of Leading Edge Slat Has Negligible Effect On The Sharing .Consistent Trends In The Measurement Of Wing Normal Load Have Been Observed With Regard To Deflection Of Rudder, Effects Of Side Slip And Installation Of Medium Range Missile. Fin Develops About 50% Of Model Side Force Under Side Slipping Conditions .With Rudder Deflection The Fin Load Sharing Varies From 80 To 180% Depending On Cc And M Correct Trend In Side Force Measurement Was Found With Regard To Anti Symmetric Deflection Of Elevons

Data Base Management And Analysis System For Wind Tunnel Results (Version-Ii,)

This Document Concerns The Details Of The Second Version Of The Data Base Management And Analysis System (DBMS) Developed At Experimental Aerodynamics Division, NAL For Wind Tunnel Test Results . Further Described In This Report Are The Batch Processing Package For Creation Of Huge Data Bases And A General Purpose, Two-Dimensional Plotting Package Which Can Be Used Independent Of Main DBMS . This Version Of DBMS Has Several New Features Compared To Earlier Version Described In Ref .1 And These Are Detailed Here . The Graphic Routines Have Been Made Highly User Friendly, Portable And Nearly Device Independent . Error Handling Routines Have Been Developed To Service The Unintentional Keyboard Errors And Wrong Inputs For Ordinal Numbers . These Have Made The System Virtually Free From Either Premature Program Shut-Down Or Producing Unexpected Results . The Current Version Of DBMS Package And The General Purpose Plotting Routines Also Work On Personal Computers And Drive A Number Of Graphical Output Devices . Additionally,A Number Of Major Data Bases Have Been Created For The Test :Data Generated Both At NAL And Elsewhere For Combat As Well As Transport Category Aircraft Models. The PC Version Of DBMS And The General Purpose Plotting Package Have Been Supplied To User Organizations

Wind Tunnel Tests On 1/20 Scale 6.45v35 Configuration Part I: Longitudinal Characteristics

Tests Were Conducted In The NAL 1 .2m Transonic Wind Tunnel On A 1/20th-Scale Model Of LCA Stage 6 .45V35 Configuration . These Tests Were Carried Out In The Mach Number Range Of 0 .3 To 1 .8 And Over An Angle Of Attack Ranges Of -2 To 24 Deg (Subsonic And Transonic Speeds) And -2 To 12 Deg (Suopersonic Speeds) . The Reynolds Number (Based On Wing Mean Aerodynamic Chord) Varied Between 3 To 7 .4 Million Depending On The Mach Number . The Results Show That This Configuration Gives On Increase In Trimmed Lift To Drag Ratio Of 11 .5% At A Lift Coefficient Of 0 .5 And Mach No. Of 0 .7 When The L.E. Slats Are Deflected From Zero To Full Angle. The L.E. Slats Also Alleviate Pitch-Up For Mach Number Below 0.95. The Addition Of Medium Range Missile Increases Both Drag And Pitching Moment Coefficient

Combined Middle Cranial Fossa and Trans-Mastoid Approach for the Management of Post-Mastoidectomy CSF Otorrhoea

Cerebrospinal fluid (CSF) otorrhoea is an uncommon condition arising from defects in the tegmen and middle cranial fossa. 33 year gentleman presented with post-mastoidectomy CSF otorrhoea of 5 year duration. Imaging finding were suggestive of fracture in the tegmen region. A combined middle cranial fossa/transmastoid was used to repair the defect. Defect was identified in the tegmen plate and it was closed with pedicled pericranial graft, laterally based pedicled temporalis muscle graft reinforced by bone dust and supported with intact mucosal flap. The leak stopped completely following surgery. The patient is doing well at follow up. Repair of these defects need careful analysis of imaging findings to understand pathological anatomy, and a well planned surgical approach to achieve meticulous repair