Euler-Stieltjes constants for the Rankin-Selberg L-function and weighted Selberg orthogonality

Let E be Galois extension of Q of finite degree and let π and π\u27 be two irreducible automorphic unitary cuspidal representations of GLm(EA) and GLm\u27(EA), respectively. We prove an asymptotic formula for computation of coefficients γπ,π\u27(k) in the Laurent (Taylor) series expansion around s=1 of the logarithmic derivative of the Rankin-Selberg L-function L(s, π × π\u27) under assumption that at least one of representations π, π\u27 is self-contragredient and show that coefficients γπ,π\u27(k) are related to weighted Selberg orthogonality. We also replace the assumption that at least one of representations π and π\u27 is self-contragredient by a weaker one

Developing the function of human resource management with a view to building competitive advantage of enterprises in Bosnia and Herzegovina

Contemporary business environment generates hyper changes and hyper competition, which is why enterprises are challenged to search for new sources to preserve and build competitive advantage in the global marketplace. In the theory and practice of management, the general view is that people and their knowledge are becoming a fundamental value in modern enterprises, and that successful human resource management is an important determinant of competitiveness. However, the importance of having specific knowledge and skills in the enterprises in Bosnia and Herzegovina (BiH) is still not recognized and human resources of these enterprises are not treated in accordance with their importance. Therefore, the objective of this paper is to point to the state and prospects of human resource development in the enterprises in BiH in the context of improving their competitiveness. This paper includes the results of one part of the empirical research covering 120 enterprises from BiH. The research was conducted in order to identify and analyze the situation in the field of key phases of human resource management in these enterprises (job analysis, human resource planning, management and selection of human resources, training and human resource development, evaluation of work performance, selection and implementation of the reward system, and management of human resource fluctuation). Based on the results, it can be concluded that the human resource management in these enterprises is underdeveloped when viewed as a special managerial function or business function, but also when treated as a separate modern business orientation in which people and their knowledge are the key value in the enterprise. The study results also show inadequate organizational treatment of human resource management in the enterprises in BiH, considering that managers’ awareness about the importance of establishing a department of human resources in these enterprises is still not sufficiently developed

Optimization of high pressure homogenization in the production of liposomal dispersions

Liposomes are spherical, biodegradable, and biocompatible vesicular systems. These vesicles are built from phospholipid double layers (membranes) surrounding the inner water phase. Liposomes are highly desirable as drug carriers because they can incorporate hydrophilic, hydrophobic and amphipathic drug substances (drugs). The physicochemical properties of liposomes such as size, charge, surface properties and encapsulation efficiency can highly influence their in vivo stability and kinetics. The aim of our study was to prepare liposomal dispersions and to determine the influence of cycles of high pres-sure homogenization on some parameters, such as vesicle size and polydispersity index (PDI). Higher homogeni-zation pressures and repeated recirculation led to further reduction in vesicle diameter and heterogeneity. For preparing liposomal dispersions Phosal IP 40 and Phosal 75 SA were used (Lipoid, Germany). Liposomal dispersions were prepared according to the thin film hydration method. By sampling after each cycle, an estimate was made of how many cycles are needed for the dispersion to have satisfactory parameters (size and PDI). The size and PDI analysis of the liposomes were carried out by using Zetasizer (Nano series) ZS 90, Malvern Instruments. High-pressure homogenization was carried out in 10 cycles and based on the obtained liposome size values and PDI, was determined how many cycles are needed in the process of homogenization. With each cycle, the size of the liposomes decreased and PDI value was reduced. It has been observed that after 5 cycles of homogenization there is no significant decrease in the size of the liposomes and PDI. Therefore, in the further production of liposomes with active substances with these raw materials, is recommended to use only 5 cycles of homogenization