Framework Guidlines and Governance for Designing Local Adaptation Plan of Action to Mainstream Climate Smart Villages in India

Based on the extensive review of existing frameworks and practices on climate change adaptation and authors experiences in Indian context, this study presented BRIFFS (bottom-up, responsive, inclusive, flexible, forward-looking, and sustainable) as the major guidelines for developing LAPA. This study presented the major steps of LAPA with clear actions, activities and also tools that can be used in each step. The nine steps of LAPA are as follows: 1) Communicating climate change risks and adaptation measures at local level, 2) Assessment of climate risks and vulnerabilities and scoping of adaptation actions, 3) Prioritisation of adaptation options, 4) Formulation of LAPA, 5) LAPA integration in planning process, 6) Institutional arrangement to implement LAPA, 7) Implementation of LAPA, 8) Progress assessment of LAPA, and 9) Feedback and revision of LAPA

Fatal anaphylactoid reaction following ioversol administration

We report a fatal intravenous ioversol administration in a 60-year old male patient. Although the introduction of new low-osmolar non-ionogenic contrast media with a more favourable efficacy-toxicity balance has diminished the side-effects significantly, everyone involved in radiodiagnostic procedures should be aware of the potential life-threatening effects. Especially patients with risk factors for side-effects should be monitored carefully

Dissecting the transcriptional networks underlying breast cancer: NR4A1 reduces the migration of normal and breast cancer cell lines

Introduction: Breast cancer currently accounts for more than one-quarter of all female cancers and, despite the great progress in treatment observed in the past few years, the need for identification of new gene targets that can be used for diagnosis, prognosis and therapy is evident. A previous study identified the transcription factor NR4A1 as a gene upregulated in primary breast cancer compared with normal tissue by microarray analysis and sequencing technologies. The purpose of the study was to identify the role of NR4A1 in normal mammary epithelial and breast cancer cell biology.Methods: NR4A1 expression in breast tumours was assessed by semiquantitative and real-time PCR using RNA from normal and tumour samples or breast cancer cell lines. Immunohistochemistry on tissue microarrays was performed to check NR4A1 protein expression in breast tumours. MCF-10A and 226L normal mammary epithelial cells as well as the tumour lines PMC42, ZR-75-1 and MDA-MB-231 were transduced with full-length NR4A1, and the ability of NR4A1-overexpressing cells to migrate was tested using scratch wound or transwell migration assays. Proliferation was measured using the MTT and BrdU assays, while apoptosis was determined by the Annexin V assay. The ability of the cells to adhere to extracellular matrix was tested by adhesion assays and integrin cell surface expression was measured by flow cytometry. Activation of the FAK as well as ERK1/2 and PI3K pathways was checked by western blotting.Results: Breast tissue microarray analysis showed NR4A1 expression in primary tumours, which was reduced in higher grade and metastatic tumours. Ectopic expression of NR4A1 in MCF-10A, 226L, PMC42 and ZR-75-1 cells led to reduced ability of the cells to migrate, while no differences were observed in their proliferation and apoptotic index. NR4A1 expression altered the ability of the MCF-10A cells to adhere to the extracellular matrix and affected cell surface expression of integrins.Conclusions: NR4A1 acts as an antimigratory factor in two normal mammary epithelial and two breast cancer cell lines tested. It is therefore possible that NR4A1 acts as an antimigratory factor in breast tumours, and further studies should be conducted to understand the mechanisms involved

Factors associated with the utilisation of postnatal care services among the mothers of Nepal: analysis of Nepal Demographic and Health Survey 2011

Background: Postnatal care is essential to save the life of the mother and newborn. Knowledge on the determinants of postnatal care assists the policy makers to design, justify and implement appropriate interventions. The current study aimed to analyse the factors associated with utilisation of postnatal care services by mothers in Nepal based on the data from Nepal Demographic and Health Survey (NDHS) 2011. Methods: This study utilised the data from NDHS 2011. The association between utilisation of at least one postnatal care visit (within 6 weeks of delivery) and immediate postnatal care (within 24 hours of delivery) with selected factors was examined by using Chi-square test (?2), followed by multiple logistic regression.Result: Of the 4079 mothers, 43.2% reported attending postnatal care within the first six weeks of birth, while 40.9% reported attending immediate postnatal care. Mothers who were from urban areas, from rich families, who were educated, whose partners were educated, who delivered in a health facility, who had attended a four or more antenatal visits, and whose delivery was attended by a skilled attendant were more likely to report attending at least one postnatal care visit. On the other hand, mothers who reported agricultural occupation, and whose partners performed agricultural occupation were less likely to have attended at least one postnatal care visit. Similarly, mothers who were from the urban areas, from rich families, who were educated, whose partners were educated, who had attended four or more antenatal visits, who delivered in a health facility and had delivered in the presence of a skilled birth attendant were more likely to report attending immediate postnatal care. Mothers who reported agricultural occupation, and whose partners performed agricultural occupation were less likely to attend immediate postnatal care. Conclusion: The majority of postnatal mothers in Nepal did not seek postnatal care. Increasing utilisation of the recommended four or more antenatal visits, delivery at health facility and increasing awareness and access to services through community-based programs especially for the rural, poor, and less educated mothers may increase postnatal care attendance in Nepal

Habitat partitioning and vulnerability of sharks in the Great Barrier Reef Marine Park

Sharks present a critical conservation challenge, but little is known about their spatial distribution and vulnerability, particularly in complex seascapes such as Australia's Great Barrier Reef Marine Park (GBRMP). We review (1) the distribution of shark species among the primary habitats of the GBRMP (coral reefs, inshore/shelf, pelagic and deep-water habitats) (2) the relative exploitation of each species by fisheries, and (3) how current catch rates interact with their vulnerability and trophic index. Excluding rays and chimaeras, we identify a total of 82 shark species in the GBRMP. We find that shark research in the GBRMP has yielded little quantitative information on most species. Reef sharks are largely site-fidelic, but can move large distances and some regularly use non-reef habitats. Inshore and shelf sharks use coastal habitats either exclusively or during specific times in their life cycle (e.g. as nurseries). Virtually nothing is known about the distribution and habitat use of the GBRMP's pelagic and deep-water sharks. At least 46 species (53.5 %) are caught in one or more fisheries, but stock assessments are lacking for most. At least 17 of the sharks caught are considered highly vulnerable to exploitation. We argue that users of shark resources should be responsible for demonstrating that a fishery is sustainable before exploitation is allowed to commence or continue. This fundamental change in management principle will safeguard against stock collapses that have characterised many shark fisheries

Prospect and potential of Burkholderia sp. against Phytophthora capsici Leonian: a causative agent for foot rot disease of black pepper

Foot rot disease is a very destructive disease in black pepper in Malaysia. It is caused by Phytophthora capsici Leonian, which is a soilborne pathogenic protist (phylum, Oomycota) that infects aerial and subterranean structures of many host plants. This pathogen is a polycyclic, such that multiple cycles of infection and inoculum production occur in a single growing season. It is more prevalent in the tropics because of the favourable environmental conditions. The utilization of plant growth-promoting rhizobacteria (PGPR) as a biological control agent has been successfully implemented in controlling many plant pathogens. Many studies on the exploration of beneficial organisms have been carried out such as Pseudomonas fluorescens, which is one of the best examples used for the control of Fusarium wilt in tomato. Similarly, P. fluorescens is found to be an effective biocontrol agent against the foot rot disease in black pepper. Nowadays there is tremendous novel increase in the species of Burkholderia with either mutualistic or antagonistic interactions in the environment. Burkholderia sp. is an indigenous PGPR capable of producing a large number of commercially important hydrolytic enzymes and bioactive substances that promote plant growth and health; are eco-friendly, biodegradable and specific in their actions; and have a broad spectrum of antimicrobial activity in keeping down the population of phytopathogens, thus playing a great role in promoting sustainable agriculture today. Hence, in this book chapter, the potential applications of Burkholderia sp. to control foot rot disease of black pepper in Malaysia, their control mechanisms, plant growth promotion, commercial potentials and the future prospects as indigenous PGPR were discussed in relation to sustainable agriculture

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Not AvailableIn the past, blanket region-based fertilizer recommendations prescribed to farmer’s that did not take into account the variations in the indigenous nutrient supply from the specific fields have led to higher production costs, diminishing yield and factor productivity, and increasing greenhouse gas emissions. Therefore, precision fertilizer recommendations that address the need-based crop requirements have been urgently needed. Site-specific nutrient management (SSNM) along with modern agronomic management practices may increase yields and nutrient use efficiency by optimizing the balance between nutrient supply and demand. In recent studies across large numbers of locations in rice/wheat-based systems in the Indo-Gangetic Plains (IGP) of India, SSNM has led to 8-12% increases in grain yields compared to farmers’ fertilizer practices/state recommended doses of fertilizers (RDF). The adoption of SSNM significantly increased the net returns by Rs. 2,500-3,200 ha-1 over farmers’ fertilizer practice by saving money on costly fertilizer inputs. Optical sensor (GreenSeeker)-based SSNM saved 20-30 kg N ha-1 without affecting grain yield under conservation agriculture (CA)-based cereal systems compared to recommended dose of fertilizers (RDF). Efficient management of N-fertilizers reduced N2O emissions by avoiding N losses via volatilization, leaching and denitrification. Site-specific nutrient management provides opportunities for enhancing crop productivity, profitability and nutrient use efficiencies (NUE) across the different ecologies. Drip irrigation system (sub-surface drip irrigation) improved the N-use efficiency by 20% over flood irrigation system in rice/maize-based systems that helped in increasing the farm profitability by saving on N-fertilizer use and water in rice-wheat/ maize-wheat systems.Not Availabl

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Not AvailableIn the Indo-Gangetic plains of South Asia, the triple challenges of diminishing farm profitability, deteriorating natural resources and energy deficits threaten conventional agricultural sustainability. This threat is intensified by the open field burning of crop residues that not only squander an indirect renewable source of energy but also impair the soil and environment quality. The crop residues can be used as organic manure by retaining the residues as mulch in the field. After a long term (5-yrs) study, it was concluded that crop residues biomass contributed maximum (∼79%) in total input energy (1,68,556 MJ ha−1) in conservation agriculture (CA) based systems, however fertilizer application (non-renewable energy source) contributed maximum (∼50%) to the total energy (40,636 MJ ha−1) in conventional tillage (CT) based maize-wheat cropping system.CA based maize systems recorded higher input energy and energy intensiveness by 23 and 57% respectively, and recorded almost 44% lower energy use efficiency and energy productivity compared to CT based maize systems. On 5 years average basis, Zero tillage based maize-wheat-mungbean with nutrient expert cropping system(ZT/MWMb + NE) utilized 351% more input energy, which resulted in25%higher output energy and 363% higher EI compared to CT/MW (40,636 MJ ha−1, 4,20,197 MJ ha−1, 39.60 MJ USD−1).Not Availabl

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Not AvailableExcessive pumping of groundwater over the years to meet the high irrigation water requirement of rice-wheat system has resulted in over exploitation of groundwater in the Indo-Gangetic plains (IGP) of India. Replacement of traditional rice with less water crops such as maize under conservation agriculture (CA) based management (tillage, crop establishment and residue management) practices are required to promote sustainable intensification. Furthermore, inefficient nutrient management practices are responsible for low crop yields and nutrient use efficiencies in MW system. A 3-year field experiment was conducted in farmer’s participatory strategic research mode at Taraori, Karnal, India to evaluate the effects of tillage and crop establishment (TCE) methods, residue management, mungbean integration, and nutrient management practices on crop yields, water productivity and profitability of MW system. The main plot treatments included four combinations of TCE, residue and mungbean integration [conventional tillage (CT), conventional tillage with mungbean (CT + MB), permanent bed (PB) and permanent bed with MB (PB + MB] with three nutrient management practices [farmer’s fertilizer practice (FFP), recommended dose of fertilize (RDF) and site specific nutrient management (SSNM)] using Nutrient Expert® as sub plot treatments. System productivity, water use efficiency (WUE) and net returns under PB + MB were significantly increased by 28.2–30.7%, 27.8–31.0% and 36.8–40.5% compared to CT respectively, during three years of experimentation. Integration of MB in MW system contributed 24.9 and 27.6% increases in system productivity and net returns compared with no MB, respectively. SSNM based nutrient management increased the mean (averaged across 3 yrs) system productivity, WUE and net returns of MW system by 13.4%, 13.3% and 15.3% compared with FFP, respectively. Study showed that conservation agriculture based sustainable intensification (PB + MB) and SSNM approach provided opportunities for enhancing crop and water use efficiency, and profitability of MW system in North-West IGP of India.Not Availabl

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Not AvailableDisposal of paddy residue has turn out to be a huge problem in north-west Indian states, resulting farmers prefer to burn the residues in-situ. Paddy residue management is of utmost important as it contains plant nutrients and improves the soil-plant-atmospheric continuum. Burning biomass not only pollutes environment and results in loss of appreciable amount of plant essential nutrients. The objectives of the review paper is to access the amount of residue generation, its utilization in-situ and ex-situ, emphasize harmful effects of residue burning on human health, soil health and environment of north-west states of India specially in Punjab and Haryana. This paper also discusses the possible strategies, financial and socio-economic evaluation of the paddy residue management technologies and accentuates the assessment of range of potential policy instruments which would offer avenues for sustainable agriculture and environment. Timely availability of conservation agriculture (CA) machinery is of utmost significance to manage the paddy residues in-situ. Collection and transportation of voluminous mass of paddy residue is cumbersome, therefore, ex-situ residue management is still not an economically viable option. The agricultural waste opens vivid options for its versatile usage and is possible if residue is collected and managed properly. It is a prerequisite for surplus residues to be used for CA. There is an urge to create awareness among farming communities to incline them to understand importance of crop residues in CA for sustainability and resilience of Indian agriculture.Not Availabl