2,343 research outputs found
An empirical biometric-based study for user identification from different roles in the online game League of Legends
© 2017 CEUR-WS. All rights reserved. The popularity of computer games has grown exponentially in the last few years. In some games, players can choose to play with different characters from a pre-defined list, exercising distinct roles in each match. Although such games were created to promote competition and promote self-improvement, there are several recurrent issues. One that has received the least amount of attention is the problem of "account sharing" so far is when a player pays more experienced players to progressing in the game. The companies running those games tend to punish this behaviour, but this specific case is hard to identify. The aim of this study is to use a database of mouse and keystroke dynamics biometric data of League of Legends players as a case study to understand the specific characteristics a player will keep (or not) when playing different roles and distinct characters
Endocytic intermediates involved with the intracellular trafficking of a fluorescent cellular prion protein
We have investigated the intracellular traffic of PrPc, a glycosylphosphatidylinositol (GPI)-anchored protein implicated in spongiform encephalopathies. A fluorescent functional green fluorescent protein (GFP)-tagged version of PrPc is found at the cell surface and in intracellular compartments in SN56 cells. Confocal microscopy and organelle-specific markers suggest that the protein is found in both the Golgi and the recycling endosomal compartment. Perturbation of endocytosis with a dynamin I-K44A dominant-negative mutant altered the steady-state distribution of the GFP-PrPc, leading to the accumulation of fluorescence in unfissioned endocytic intermediates. These pre-endocytic intermediates did not seem to accumulate GFP-GPI, a minimum GPI-anchored protein, suggesting that PrPc trafficking does not depend solely on the GPI anchor. We found that internalized GFP-PrPc accumulates in Rab5-positive endosomes and that a Rab5 mutant alters the steady-state distribution of GFP-PrPc but not that of GFP-GPI between the plasma membrane and early endosomes. Therefore, we conclude that PrPc internalizes via a dynamin-dependent endocytic pathway and that the protein is targeted to the recycling endosomal compartment via Rab5-positive early endosomes. These observations indicate that traffic of GFP-PrPc is not determined predominantly by the GPI anchor and that, different from other GPI-anchored proteins, PrPc is delivered to classic endosomes after internalization
Perceptions of nursing undergraduate students concerning the human dimension in the learning process
The Underestimation Of Egocentric Distance: Evidence From Frontal Matching Tasks
There is controversy over the existence, nature, and cause of error in egocentric distance judgments. One proposal is that the systematic biases often found in explicit judgments of egocentric distance along the ground may be related to recently observed biases in the perceived declination of gaze (Durgin & Li, Attention, Perception, & Psychophysics, in press), To measure perceived egocentric distance nonverbally, observers in a field were asked to position themselves so that their distance from one of two experimenters was equal to the frontal distance between the experimenters. Observers placed themselves too far away, consistent with egocentric distance underestimation. A similar experiment was conducted with vertical frontal extents. Both experiments were replicated in panoramic virtual reality. Perceived egocentric distance was quantitatively consistent with angular bias in perceived gaze declination (1.5 gain). Finally, an exocentric distance-matching task was contrasted with a variant of the egocentric matching task. The egocentric matching data approximate a constant compression of perceived egocentric distance with a power function exponent of nearly 1; exocentric matches had an exponent of about 0.67. The divergent pattern between egocentric and exocentric matches suggests that they depend on different visual cues
Ultrasonography of the distal limbs in Nellore and Girolando calves 8 to 12Â months of age
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Previous issue date: 2014Background: Ultrasonography can be used anywhere and allows rapid, noninvasive differentiation of soft tissue
structures of the musculoskeletal system. The objectives of this study were to describe the ultrasonographic
appearance of the structures of the metacarpo-/metatarsophalangeal and the interphalangeal joints, the appearance of
the growth plates of the distal metacarpus/metatarsus and of the proximal phalanx and to measure the
cross-sectional dimensions of the DDFT and SDFT in Nellore and Girolando calves eight to 12 months of age.
Results: In the longitudinal dorsal view the common digital extensor tendon and the digital extensor tendon were
depicted as echogenic parallel fiber bundles located directly under the skin. The joint spaces appeared as anechoic
interruptions of the hyperechogenic bone surfaces. The normal amount of synovial fluid could not be depicted.
The growth plates were seen as anechoic interruptions of the bone surface proximal and distal to the fetlock joint
space. In transverse sonograms of the distal palmar/plantar regions, the flexor tendons and branchs of the
suspensory ligament were imaged as echogenic structures. The lumen of the digital flexor tendon sheath could
not be imaged in these normal cattle. The thin digital distal annular ligament and the reversal of positions of the
DDFT and SDFT could be appreciated. No significant differences were found between the cross-sectional measurements
of the DDFT and the SDFT from Nellore and Girolando in any age, thoracic/pelvic limbs, right/left sides and
lateral/medial digits.
Conclusions: The results of this study establish important ultrasonographic reference data of the normal structures of
the distal limbs and the normal dimensions of the flexor tendons in Nellore and Girolando calves for use in clinical
practice
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