673 research outputs found
Towards Social Security Systems in Japan Lessons for India
Japan has to restructure its social security systems fromtime to time for different reasons like a far more rapid aging of population , the slow down of long term economic growth and deteriorating equity in the inter-generational transfer of welfare .But even then, the basic elements remain the same .It si pertinent to see how and to whar extent japan’s social security systems could be translated in the case of India. As apreliminary analysis ,in section One, attempt has been made to summarize the distinctive features of social security systems in Japan.Section Two dwells upon the nature and problems of the social security systems in India. An endeavour has been made in Section three to articulate on the lessons for India. Final Section Four concludes and summarizes the main findings.It has ben observed that there are certain experiences that India can learn ,amongothers, the careful application of universal social security systems, the role of insurance policies,private-public synergies ,the role of the government and governance, the importance attached to social capital.Universal social security system, private–public partnership, Inter-generational Equity governance, social capital
Co-Activation of TGFβ and Wnt Signalling Pathways Abrogates EMT in Ovarian Cancer Cells
The aggressive property of ovarian cancer (OC) in terms of epithelialmesenchymal transition (EMT), proliferation and metastasis are of major concern. Different growth factors including TGFβ are associated with regulating these molecular events but the underlying mechanisms remain unclear. The aim of this report is to decipher the regulation of EMT by co-activation of TGFβ and Wnt signalling cascades in gaining malignancy. Methods:
The expression of the different components of signalling events were analyzed by QPCR, Western blot, Immunofluorescence microscopy and flow cytometry. β-catenin promoter activity was checked by luciferase assay. Results: We observed reduced EMT in ovarian cancer cells upon co-activation with TGFβ1 and LiCl as shown by the expressions of epithelial/ mesenchymal markers and the EMT promoting factor, Snail1, accompanied by decrease in the invasion and migration of the cells compared to individual pathway activation. A detailed study of the mechanism suggested reduction in the β-catenin and p-GSK3b (Ser 9) levels
to be the driving cause of this phenomenon, which was reversed upon co-activation with higher concentrations of LiCl. Conclusions: Therefore, tumourigenesis might be affected by the concentration of ligand/ growth factors for the respective signalling pathways activated in the tumour microenvironment and interaction between them might alter tumourigenesis
Tuberculin screening of some selected Fulani lactating cows in north-central Nigeria
The prevalence of mycobacterial infection among lactating Fulani cows was investigated in the Federal Capital Territory, Abuja and Kaduna State of Nigeria. Tuberculin testing using single comparative intradermal tuberculin test showed a 14.6 % positive, 4 % doubtful, and 81.4 % negative reactors. Mycobacterial infection was found to be present in the nomadic (constantly moving) and seminomadic (limited movement) management systems studied but management showed no significant effect on the prevalence of the disease. However, the prevalence was significantly higher in older age groups than the younger ones (P < 0.05).Peer reviewedSubmitted Versio
Prevalence of bovine tuberculosis using single comparative intradermal tubeculin test (SCITT) in Fulani herds in Nasarawa state, north central Nigeria
In a study to determine the prevalence of bovine tuberculosis in the cattle population of Nasarawa State, 199 cattle were randomly selected and screened using the Single Comparative Intradermal Tuberculin Test (SCITT).A 15.08% reactor rate was observed in the cattle screened. While the bulls and calves had 1.00% and 2.51% reactor rate respectively. The cows had as high as 11.56% which is statistically significant (P.0.05). The infected cows would continue to be the source of infection to susceptible cattle especially the calves and humans. Control measures such as public enlightenment, mandatory pasteurization of milk before sale to the public and trace back of infected carcass to the herd with subsequent test and slaughter with full compensation have been suggested
On the translaminar fracture toughness of vectran/epoxy composite material
The mode I fracture toughness associated with fibre tensile failure was investigated for a Vectran/MTM57 composite system. A modified compact tension specimen was designed and manufactured to mitigate compressive and buckling failure due to the low compressive properties which are an inherent characteristic of Vectran fibres. On average, the mode I translaminar fracture toughness for Vectran/MTM57 was found to be approximately 130–145 kJ/m2 for initiation and 250–260 kJ/m2 for propagation. In contrast with other composite systems such as carbon and glass fibre, the fracture toughness of Vectran/MTM57 was found to be relatively higher, with up to 48.26% and 95.27% for initiation and propagation, respectively for some carbon fibre composite system; 9.93% and 68.6% for initiation and propagation, respectively for S2-Glass/epoxy system
Reporte mensual - Mayo 2018
Reporte mensual de la actividad de publicación a través del SiB ColombiaBogotá, Colombi
Reporte mensual - Octubre 2017
Reporte mensual de la actividad de publicación a través del SiB ColombiaBogotá, Colombi
Reporte mensual - Junio 2016
Reporte mensual de la actividad de publicación a través del SiB ColombiaBogotá, Colombi
Reporte mensual - Abril 2018
Reporte mensual de la actividad de publicación a través del SiB ColombiaBogotá, Colombi
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