Annihilation of vortex dipoles in an Oblate Bose-Einstein Condensate

We theoretically explore the annihilation of vortex dipoles, generated when an obstacle moves through an oblate Bose-Einstein condensate, and examine the energetics of the annihilation event. We show that the gray soliton, which results from the vortex dipole annihilation, is lower in energy than the vortex dipole. We also investigate the annihilation events numerically and observe that the annihilation occurs only when the vortex dipole overtakes the obstacle and comes closer than the coherence length. Furthermore, we find that the noise reduces the probability of annihilation events. This may explain the lack of annihilation events in experimental realizations.Comment: 8 pages and 9 figure

A kinetic scheme with variable velocities and relative entropy

A new kinetic model is proposed where the equilibrium distribution with bounded support has a range of velocities about two average velocities in 1D. In 2D, the equilibrium distribution function has a range of velocities about four average velocities, one in each quadrant. In the associated finite volume scheme, the average velocities are used to enforce the Rankine-Hugoniot jump conditions for the numerical diffusion at cell-interfaces, thereby capturing steady discontinuities exactly. The variable range of velocities is used to provide additional diffusion in smooth regions. Further, a novel kinetic theory based expression for relative entropy is presented which, along with an additional criterion, is used to identify expansions and smooth flow regions. Appropriate flow tangency and far-field boundary conditions are formulated for the proposed kinetic model. Several benchmark 1D and 2D compressible flow test cases are solved to demonstrate the efficacy of the proposed solver.Comment: 53 page

A rare case of vulval leiomyoma

Vulval leiomyomas are rare smooth muscle tumors that may arise from smooth muscle cells within erectile tissue, blood vessel wall or round ligament remnants in the labia majora and they are clinically misdiagnosed as Bartholin cyst or lipoma. In our case, a 40-year-old woman presented with 8 years history of progressively increasing painless swelling on her vulva. Clinically it was diagnosed as a solid tumour due to its consistency and location. Hence surgical excision was done. Histopathology report was suggestive of leiomyoma with hyaline changes on microscopy. Major diagnostic problem with smooth muscle tumors of the vulva is the distinction between benign and malignant form, since many vulval lesions have similar appearances making it difficult to distinguish benign from malignant lesions by gross inspection. The recommended treatment option is local excision of the mass with pathological examination

Analysis of Quantity Space Hierarchy in Cc

Computer Science

Multiple Myeloma with Subtrochanteric Femur Fracture and Shaft of Humerus Fracturetreated with Single Stage IMIL Nailing: A Case Report

Plasma cell dyscrasia include multiple entities from benign plasmacytoma to malignant multiple myeloma. According to literature, about 45% of patients with multiple myeloma experience a fracture in the first year after diagnosis and 65% of patients experience a fracture during the course of the disease. The pathological fracture requires immediate fixation according to Mirell’s scoring considering the natural course of the disease and short life expectancy associated with multiple myeloma. Here, we would like to specify a case of multiple myeloma with extensive lytic lesions throughout the body, wherein subtrochanteric femur and shaft of humerus required fixation according to Mirell’s scoring (2). We did a single stage intramedullary nailing for subtrochanteric femur fracture and shaft of humerus with 12 and 10 Mirell’s score respectively, with no complications in the outcome with regards to pain and quality of life, the fractures go on to unite well

A prospective observational study of prescription appropriateness of elderly hypertensive patients using Beers criteria in a tertiary care teaching hospital

Background: The prevalence of hypertension has been increased among the urban population especially among the elderly. Use of inappropriate medication is one of the major problems seen among elderly age group above 60 years who take more medication when compared to that of younger population. Inappropriate prescriptions can be avoided by identifying safer pharmacological alternatives and also utilizing non-pharmacological therapy. Quality and safety of prescribing in elderly patients is one of the global healthcare concern and efforts should be made to improve appropriateness of medication among this group of population. This study was done to assess the relationship between inappropriate medication use and its health outcomes in elderly hypertensive population.Methods: A prospective observational study was conducted over a period of 3 months, after getting approval from Institutional Ethics Committee. Total of 117 elderly hypertensive patients aged >60 years were analysed for three months duration for the rationality of medication prescribed using Beer’s criteria and the health outcome due to inappropriate medication use.Results: Out of 117 elderly hypertensive patients analysed, 49 (41.9%) were males and 68 (58.1%) were females. Most of the patients had associated co morbid illness like diabetes mellitus (48.7%), respiratory diseases (24.8%), cerebrovascular accident (30.8%), cardiovascular diseases (19.7%), fever (13.7%), anaemia (9.4%), etc. Out of 117 patients 10 drugs were used in 3.4% of cases. Antihypertensive drugs that were commonly used in our study was calcium channel blocker (52.1%), diuretics (42.7%), Angiotensin converting enzyme inhibitors (36.8%), β-blockers (17.1%) and Angiotensin receptor blockers (11.1%). Adverse health effects like drug induced gastritis, electrolyte imbalance, metabolic dysfunction and renal impairment was seen in few patients because of inappropriate medication.Conclusions: Use of inappropriate medication is one of the major problems seen among elderly, because of the co morbid illness associated with the primary disease which leads to polypharmacy. Prescription inappropriateness was seen among 86.3% of elderly hypertensive patients as per Beers criteria which may be because of comorbid illness that was seen among these patients. It is necessary to implement certain policies in geriatric healthcare to prevent the poor outcome due to drug therapy.

Modulation of Immune Responses by Particle Size and Shape

The immune system has to cope with a wide range of irregularly shaped pathogens that can actively move (e.g., by flagella) and also dynamically remodel their shape (e.g., transition from yeast-shaped to hyphal fungi). The goal of this review is to draw general conclusions of how the size and geometry of a pathogen affect its uptake and processing by phagocytes of the immune system. We compared both theoretical and experimental studies with different cells, model particles, and pathogenic microbes (particularly fungi) showing that particle size, shape, rigidity, and surface roughness are important parameters for cellular uptake and subsequent immune responses, particularly inflammasome activation and T cell activation. Understanding how the physical properties of particles affect immune responses can aid the design of better vaccines