Cultivation potential of culinary bamboos in Southern India

237-239India is one of the leading countries of the world, second only to China, in bamboo production with a figure of 32.3 million tonnes/year. Bamboo species cover an area of around 10.03 million hectares, which contribute 12.8% of the total forest cover of the country. In bamboo diversity India ranks third i.e. next to China (300 species) and Japan (237 species). More than 70 genera and 1,200 species of bamboo have been described, but only a few are grown commercially for their shoots

Influence of age on fibre and chemical characteristics of plantation crop of Bamboo

No Abstract Available E. Afr. Agric. For. J Vol.68(4) 2003: 165-16

www.omicsonline.com Research Article Computational Annotation for Hypothetical Proteins of Mycobacterium Tuberculosis

Copyright: © 2008 Anandakumar S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. There is rising death of humans worldwide by reason of tuberculosis. The current sequencing of the Mycobacterium tuberculosis genome holds assure for the development of new vaccines and the design of new drugs. In this view, the functions prediction of genomic sequences for hypothetical proteins will invigorate our knowledge with reference to the identification of new drugs for tuberculosis. There are various function prediction methods available based on the on the assumption. The process accurate annotation for genes in newly sequenced genomes currently has been based on sequence similarity. In this work about 250 hypothetical proteins of Mycobacterium tuberculosis taken functions were predicted using Bioinformatics web tools, BLAST, INTERPROSCAN, PFAM and COGs

Florisitic structure and biomass distribution of a tropical seasonal rainforest in Xishuangbanna, southwest China

The aim of this research was to study the forest community structure, tree species diversity and biomass production of a tropical seasonal rain forest in Xishuangbanna, southwest China. The community structure showed a diversified species composition and supported many species of economic significance. This tropical rain forest is closely related to Malaysian forests. The biomass and its distribution were studied using standard regression analysis and the clear-cut method for shrubs and herbs. The total biomass was 360.9 t/ha and its allocation in different layers was: tree layer 352.5 t/ha, shrub layer 4.7 t/ha, liana 3.1 t/ha and herb layer 0.5 t/ha. Most of the biomass was concentrated in the trees: stem 241.2 t/ha, root 69.6 t/ha, branch 37.2 t/ha and leaves 4.3 t/ha; The DBH class allocation of the tree biomass was concentrated in the middle DBH class. The biomass of six DBH classes from 20 to 80 cm was 255.4 t/ha. There are twenty-six species with biomass over 0.5% of the total biomass of the tree layer, and three species with biomass over 5%, i.e., Pometia tomentosa, Barringtonia macrostachya (5.4%) and Terminalia myriocarpa (5.2%). Data on stem, branch, leaves and root of the individual tree species were used to develop regression models. D2H was found to be the best estimator of the biomass in this tropical rain forest. However, higher biomass figures have been reported from tropical forests elsewhere e.g., 415–520 t/ha in the tropical forests of Cambodia, the tropical moist mixed dipterocarp forests, and the tropical moist logged moist evergreen-high, medium, and low yield forests of SriLanka. In some forests, lower accumulation of biomass was reported, e.g., 10–295 t/ha in the tropical moist forests of Bangladesh, the tropical moist dense forest of Cambodia, the tropical dry forests of India, the tropical moist forests of Penninsular-Malaysia, the tropical moist mixed dipterocarps forests of Sarawak-Malaysia, the tropical evergreen forests of Myanmar and the tropical moist ever-green logged forests of SriLanka

An expedient synthesis of isoxazolo - and pyrazolo-[3,4-<em>a</em>]acridines with molecular docking studies

345-354An efficient synthesis of isoxazolo[3,4-a]acridines from 7-chloro-9-phenyl-2-(aryl-2'-ylmethylene)-3,4-dihydroacridin-1(2H)-one obtained from 7-chloro-9-phenyl-3,4-dihydroacridin-1(2H)-one with arylaldehyde in presence of alcoholic sodium hydroxide at room temperature on reaction with hydroxylamine hydrochloride in pyridine is reported. Further the synthesis of pyrazolo[3,4-a]acridines has been achieved in a single step from 3,4-dihydroacridin-1(2H)-ones on Claisen condensation with ethyl formate/sodium hydride in toluene followed by hydrazine hydrate treatment. The synthesized eighteen compounds have been further attested by advanced spectral and analytical techniques and their molecular docking studies with structure activity relationship (SAR) studies are reported

Molecule modeling of human pentameric alpha(7) neuronal nicotinic acetylcholine receptor and its interaction with its agonist and competitive antagonist

The nicotinic Acetylcholine Receptor (nAChR) is the major class of neurotransmitter receptors that is involved in many neurodegenerative conditions such as schizophrenia, Alzheimer's and Parkinson's diseases. The N-terminal region or Ligand Binding Domain (LBD) of nAChR is located at pre- and post-synaptic nervous system, which mediates synaptic transmission. nAChR acts as the drug target for agonist and competitive antagonist molecules that modulate signal transmission at the nerve terminals. Based on Acetylcholine Binding Protein (AChBP) from Lymnea stagnalis as the structural template, the homology modeling approach was carried out to build three dimensional model of the N-terminal region of human alpha(7)nAChR. This theoretical model is an assembly of five alpha(7) subunits with 5 fold axis symmetry, constituting a channel, with the binding picket present at the interface region of the subunits. alpha-netlrotoxin is a potent nAChR competitive antagonist that readily blocks the channel resulting in paralysis. The molecular interaction of alpha-Bungarotoxin, a long chain alpha-neurotoxin from (Bungarus multicinctus) and human alpha(7)nAChR seas studied. Agonists such as acetylcholine, nicotine, which are used in it diverse array of biological activities, such as enhancements of cognitive performances, were also docked with the theoretical model of human alpha(7)nAChR. These docked complexes were analyzed further for identifying the crucial residues involved in interaction. These results provide the details of interaction of agonists and competitive antagonists with three dimensional model of the N-terminal region of human alpha(7)nAChR and thereby point to the design of novel lead compounds

<span style="font-size:10.0pt;font-family: "Times New Roman";mso-fareast-font-family:"Times New Roman";mso-bidi-font-family: Mangal;mso-ansi-language:EN-US;mso-fareast-language:EN-US;mso-bidi-language: HI" lang="EN-US">Quinoline alkaloids – Synthesis, molecular docking studies of atanine, 2-isopropylfuro [2,3-<i style="mso-bidi-font-style:normal">b</i>] quinolines and 3,4-dihydro-2,2-dimethyl-2<i style="mso-bidi-font-style:normal">H</i>-pyrano [2,3-<i style="mso-bidi-font-style:normal">b</i>]quinolines</span>

988-998A simple and efficient route to synthesis of 3-prenyl-2-quinolinones, 2-isopropyl-furo[2,3-b]quinolines and 3,4-dihydro- 2,2-dimethyl-2H-pyrano[2,3-b]quinolines has been developed. 3(1'-Carboxy-3-methylbut-1'-enyl)-2-quinolinones have been decarboxylated using ethanolamine followed by Prevost’s reaction with HgO/I2/AcOH and AgOAc/I2/AcOH to yield 2-isopropyl-furo[2,3-b] quinolines and which on cyclization using a few drops of conc.H2SO4 in ethanol give 3,4-dihydro-2,2-dimethyl-2H-pyrano[2,3-b]quinolines. All the synthesized compounds have been structurally well characterized by spectral studies. The intermediates, 3-prenyl-2-quinolinones, were isolated and characterized. Subsequently the molecular docking studies for the first time have been carried out for all the synthesized compounds using the protein kinase Epidermal Growth Factor Receptor (EGFR) inhibitors

Gardeners training

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