Einstein and Jordan frames reconciled: a frame-invariant approach to scalar-tensor cosmology

Scalar-Tensor theories of gravity can be formulated in different frames, most notably, the Einstein and the Jordan one. While some debate still persists in the literature on the physical status of the different frames, a frame transformation in Scalar-Tensor theories amounts to a local redefinition of the metric, and then should not affect physical results. We analyze the issue in a cosmological context. In particular, we define all the relevant observables (redshift, distances, cross-sections, ...) in terms of frame-independent quantities. Then, we give a frame-independent formulation of the Boltzmann equation, and outline its use in relevant examples such as particle freeze-out and the evolution of the CMB photon distribution function. Finally, we derive the gravitational equations for the frame-independent quantities at first order in perturbation theory. From a practical point of view, the present approach allows the simultaneous implementation of the good aspects of the two frames in a clear and straightforward way.Comment: 15 pages, matches version to be published on Phys. Rev.

Dynamical Relaxation of the Dark Matter to Baryon Ratio

A scalar field interacting differently with dark matter and baryons may explain why their ratio is of order unity today. We provide three working examples, checking them against the observations of CMB, Large Scale Structure, supernovae Ia, and post-newtonian tests of gravity. Such a scenario could make life much easier for supersymmetric dark matter candidates.Comment: 7 pages, 5 .eps figures. Discussion of the approach of the field to the fixed point added. Figures modified accordingly. Conclusions unchanged. Version to be published on Phys Rev.

Axion-Dilaton Cosmology and Dark Energy

We discuss a class of flat FRW cosmological models based on D=4 axion-dilaton gravity universally coupled to cosmological background fluids. In particular, we investigate the possibility of recurrent acceleration, which was recently shown to be generically realized in a wide class of axion-dilaton models, but in absence of cosmological background fluids. We observe that, once we impose the existence of radiation -and matter- dominated earlier stages of cosmic evolution, the axion-dilaton dynamics is altered significantly with respect to the case of pure axion-dilaton gravity. During the matter dominated epoch the scalar fields remain either frozen, due to the large expansion rate, or enter a cosmological scaling regime. In both cases, oscillations of the effective equation of state around the acceleration boundary value are impossible. Models which enter an oscillatory stage in the low redshift regime, on the other hand, are disfavored by observations. We also comment on the viability of the axion-dilaton system as a candidate for dynamical dark energy. In a certain subclass of models, an intermediate scaling regime is succeeded by eternal acceleration. We also briefly discuss the issue of dependence on initial conditions.Comment: 28 pages, 11 figure

Quantitative analysis of dynamic computed tomography angiography for the detection of endoleaks after abdominal aorta aneurysm endovascular repair:A feasibility study

ObjectivesTo assess the feasibility of quantitative analysis of dynamic computed tomography angiography (dCTA) for the detection of endoleaks in patients who underwent endovascular repair of abdominal aortic aneurysms (EVAR).Material and methodsTwenty patients scheduled for contrast-enhanced CT angiography (CTA) of the abdominal aorta post-EVAR were prospectively enrolled. All patients received a standard triphasic CTA protocol, followed by an additional dCTA. The dCTA acquisition enabled reconstruction of color-coded maps depicting blood perfusion and a dCTA dataset of the aneurysm sac. Observers assessed the dCTA and dynamic CT perfusion (dCTP) images for the detection of endoleaks, establishing diagnostic confidence based on a modified 5-point Likert scale. An index was calculated for the ratio between the endoleak and aneurysm sac using blood flow for dCTP and Hounsfield units (HU) for dCTA. The Wilcoxon test compared the endoleak index and the diagnostic confidence of the observers.ResultsIn total, 19 patients (18 males, median age 74 years [70.5-75.7]) were included for analysis. Nine endoleaks were detected in 7 patients using triphasic CTA as the reference standard. There was complete agreement for endoleak detection between the two techniques on a per-patient basis. Both dCTA and dCTP identified an additional endoleak in one patient. The diagnostic confidence using dCTP for detection of endoleaks was not significantly superior to dCTA (5.0 [5-5] vs. 4.5 [4-5], respectively; p = 0.11); however, dCTP demonstrated superior diagnostic confidence for endoleak exclusion compared to dCTA (1.0 [1-1] vs 1.5 [1.5-1.5], respectively; p ConclusionsQuantitative analysis of dCTP imaging can aid in the detection of endoleaks and demonstrates a higher endoleak detection rate than triphasic CTA, as well as a strong correlation with visual assessment of dCTA images

Nature-Based Solutions Are Critical for Putting Brazil on Track Towards Net Zero

Over 130 countries have committed to reaching net-zero CO2 or GHG emissions by 2050, yet this ambition is rarely underpinned by robust policies. By applying a detailed integrated assessment modelling approach for Brazil, we assess, for the first time, the extent to which the existing and planned local policies could put Brazil on the path to its net zero pledge. This includes quantifying the role of nature-based solutions, such as protection and restoration, and engineered solutions, such as bioenergy with carbon capture and storage (BECCS). We show protection is the single most important climate mitigation measure at relatively low costs, whereas relying heavily on engineered solutions would jeopardise Brazil’s chances of achieving its net zero pledge. We also show that the mismatch between Brazil's short- and long-term climate targets reflects current weak environmental governance. Our analysis reinforces the urgent need for Brazil to eliminate illegal deforestation and go beyond to help fight climate change whilst curbing biodiversity loss

Piroxicam and intracavitary platinum-based chemotherapy for the treatment of advanced mesothelioma in pets: preliminary observations

Malignant Mesothelioma is an uncommon and very aggressive tumor that accounts for 1% of all the deaths secondary to malignancy in humans. Interestingly, this neoplasm has been occasionally described in companion animals as well. Aim of this study was the preclinical evaluation of the combination of piroxicam with platinum-based intracavitary chemotherapy in pets. Three companion animals have been treated in a three years period with this combination. Diagnosis was obtained by ultrasonographic exam of the body cavities that evidenced thickening of the mesothelium. A surgical biopsy further substantiated the diagnosis. After drainage of the malignant effusion from the affected cavity, the patients received four cycles of intracavitary CDDP at the dose of 50 mg/m2 every three weeks if dogs or four cycles of intracavitary carboplatin at the dose of 180 mg/m2 (every 3 weeks) if cats, coupled with daily administration of piroxicam at the dose of 0.3 mg/kg. The therapy was able to arrest the effusion in all patients for variable remission times: one dog is still in remission after 3 years, one dog died of progressive disease after 8 months and one cat died due to progressive neoplastic growth after six months, when the patient developed a mesothelial cuirass. The combination showed remarkable efficacy at controlling the malignant effusion secondary to MM in our patients and warrants further investigations

Desafios do cumprimento da NDC brasileira no bioma Amazônia.

Resumo: A Contribuição Nacionalmente Determinada (NDC) brasileira estabeleceu metas ambiciosas de redução de emissões de gases de efeito estufa. Este artigo avalia os desafios para cumprimento da NDC na redução do desmatamento e restauração florestal no bioma Amazônia. O diagnóstico inédito considera a extensão do desmatamento ilegal e os déficits e excedentes de reserva legal por tamanho de propriedade e tipo de uso da terra

Physiological Benefits of Being Small in a Changing World: Responses of Coho Salmon (Oncorhynchus kisutch) to an Acute Thermal Challenge and a Simulated Capture Event

Evidence is building to suggest that both chronic and acute warm temperature exposure, as well as other anthropogenic perturbations, may select for small adult fish within a species. To shed light on this phenomenon, we investigated physiological and anatomical attributes associated with size-specific responses to an acute thermal challenge and a fisheries capture simulation (exercise+air exposure) in maturing male coho salmon (Oncorhynchus kisutch). Full-size females were included for a sex-specific comparison. A size-specific response in haematology to an acute thermal challenge (from 7 to 20°C at 3°C h−1) was apparent only for plasma potassium, whereby full-size males exhibited a significant increase in comparison with smaller males (‘jacks’). Full-size females exhibited an elevated blood stress response in comparison with full-size males. Metabolic recovery following exhaustive exercise at 7°C was size-specific, with jacks regaining resting levels of metabolism at 9.3±0.5 h post-exercise in comparison with 12.3±0.4 h for full-size fish of both sexes. Excess post-exercise oxygen consumption scaled with body mass in male fish with an exponent of b = 1.20±0.08. Jacks appeared to regain osmoregulatory homeostasis faster than full-size males, and they had higher ventilation rates at 1 h post-exercise. Peak metabolic rate during post-exercise recovery scaled with body mass with an exponent of b∼1, suggesting that the slower metabolic recovery in large fish was not due to limitations in diffusive or convective oxygen transport, but that large fish simply accumulated a greater ‘oxygen debt’ that took longer to pay back at the size-independent peak metabolic rate of ∼6 mg min−1 kg−1. Post-exercise recovery of plasma testosterone was faster in jacks compared with full-size males, suggesting less impairment of the maturation trajectory of smaller fish. Supporting previous studies, these findings suggest that environmental change and non-lethal fisheries interactions have the potential to select for small individuals within fish populations over time