Book Review: Behind the Gates: Life, Security, and the Pursuit of Happiness in Fortress America

Review of Behind the Gates: Life, Security, and the Pursuit of Happiness in Fortress America by Setha Lo

Predictors of barriers to participation in clinical research in adults living in the Southeastern United States

Research is the necessary foundation for health care advancement and understanding. Significant challenges exist, however, with recruiting and engaging underrepresented populations in clinical research. The purpose of the scholarly project was to determine how stakeholder race, trust, and level of education influence participation barriers in clinical research. The project utilized secondary, cross sectional survey data that were collected between 2014 and 2016 through the former Mid-South Clinical Data Research Network (CDRN), currently known as the STAR-CRN. Descriptive statistics and spearman rank correlations were performed between level of education, level of trust, and each attitude statement for each racial category. A total of 2,149 survey responses were used in the data analysis. The mean age of respondents was 52 years old (SD=15.65) with majority being female (69.0%, n=1496), white (77.7%, n=1701), insured (76%, n=1610), and working full time (50.4%, n=1078). Overall, the respondents had favorable attitudes towards research participation. Trust was associated with agreement in each attitude statement from both white and AA respondents (pCC=-.492; p=.000), AA (CC=-.188; p=.000), Asian (CC=-.429; p=.041), and Middle Eastern (CC=-.864; p=.003) respondents. The results support the importance of trust within the patient and provider relationship. Generally, education level is not a largely predictive variable in its influence of research participation, although it shows stronger evidence of influence depending on race and attitude statement. Keywords: trust, race, education, participation, clinical research, underrepresented, adult

(In)visible Witnesses: Young people's views of images of scientists, technologists, engineers and mathematicians on UK children's television from a gender perspective (Research Briefing)

This briefing is based on the (In)visible Witnesses study by a team of researchers led by Liz Whitelegg and Richard Holliman at the Open University. This project is one of five commissioned by the UKRC to explore issues around the role of the media and representations of women in STEM. This briefing looks at the (re)construction of gendered representations of STEM on children's television and investigates the ways in which these images affected children's and young people's perceptions of STEM. The content of two weeks of children's television was analysed. Following this, 45 children and young people were involved in a study which looked at how children and young people made sense of the STEM they watch on television. Several methods were used to elicit children's and young people's perceptions of STEM and their place within these fields in the future - a questionnaire, 'draw-a-scientist' test, reflective writing about their future selves as scientists and the creation of a 'storyboard' for a TV programme

How Young People Save Money: Findings From Interviews With SEED Participants

How Young People Save Money: Findings From Interviews With SEED Participant

Future of Veterinary Medicine Explored at Student-Planned Conference

The future is about hard work, new leadership, and organizational models that need to change. It\u27s about changing our scope and our influences while concurrently functioning and changing in a world where our future is in a fast-forward mode

Interrogating fragments using a protein thermal shift assay

Protein thermal shift is a relatively rapid and inexpensive technique for the identification of low molecular weight compound interactions with protein targets. An increase in the melting temperature of the target protein in the presence of a test ligand is indicative of a promising ligand-protein interaction. Due to its simplicity, protein thermal shift is an attractive method for screening libraries and validating hits in drug discovery programs. The methodology has been used successfully in high throughput screens of small molecule libraries, and its application has been extended to report on protein-drug-like-fragment interactions. Here, we review how protein thermal shift has been employed recently in fragment-based drug discovery (FBDD) efforts, and highlight its application to protein-protein interaction targets. Multiple validation of fragment hits by independent means is paramount to ensure efficient and economical progress in a FBDD campaign. We discuss the applicability of thermal shift assays in this light, and discuss more generally what one does when orthogonal approaches disagree

(In)visible Witnesses: Investigating gendered representations of scientists, technologists, engineers and mathematicians on UK children's television

How do the images that children see on TV influence their interest in science, technology, engineering or mathematics? This report provides details of the (In)visible Witnesses research project, led by members of the Open University's Centre for Research in Education and Educational Technology, that looked at how frequently images of scientists, technologists, engineers and mathematicians are are shown on children's television, how scientists, technologists, engineers and mathematicians are represented within these images and explored how children and young people interpret and contextualise such images

Improving professional learning and teaching through the development of a quality process

Investigation of graduate attributes (GAs) and professional standards (PSs) within faculty curriculum development are rare, despite university importance. Examining learning objectives and assessment with PSs and accreditation, this project sought learning and teaching improvements through developing a cross discipline quality assurance process, aligning learning and assessment with PSs and GAs. This paper describes the results of interviews with those responsible for teaching and learning in four faculties at an Australian University. The results indicate that curriculum developers are often unable to align the GAs and PSs that creates challenges for an assurance of students’ learning

(In)visible Witnesses: Drawing on young people’s media literacy skills to explore gendered representations of science, technology, engineering and mathematics

This report describes further work on the (In)visible Witnesses project and so continues the work described in the first report (In)visible witnesses: Investigating gendered representations of scientists, technologists, engineers and mathematicians on UK children’s television (Whitelegg et. al, 2008). It should therefore be read alongside this earlier report where the background and rationale for the project as a whole is described. A link to this report can be found below, under "Related URLs". The aims of the work described in the report, however, remain the same as those of the original study: 1. Study the (re)construction of gendered representations of science, technology, engineering and mathematics (STEM) on UK television, i.e. to investigate the continuing portrayal of established stereotypes of STEM and document the emergence of new images. 2. Investigate the extent to which these images might affect children and young people’s perceptions of STEM

Backbone and side chain H-1, N-15 and C-13 assignments for the oxidised and reduced forms of the oxidoreductase protein DsbA from Staphylococcus aureus

The function and dynamics of the thiol-disulfide oxidoreductase DsbA in the low-GC gram positive bacterium, Staphylococcus aureus, are yet to be elucidated. Here we report 13C, 15N and 1H assignments for the oxidised and reduced forms of SaDsbA as a prelude to further studies on the enzyme