On a class of translation planes of square order

AbstractA class of translation planes of order q2, where q = pr, p is a prime, p ⩾7, p ≠± 1 (mod 10) and r is an odd natural number is constructed and the translation complements of these planes are determined. A property shared by all these planes is that the translation complement fixes a distinguished point and divides the remaining distinguished points into two orbits of length q and q2 − q. The order of the translation complement is rq(q − 1)2 except for q = 7 and q = 13. The translation complements of these exceptional cases are also briefly studied. The class of planes considered in this paper are distinct from the classes of translation planes of S.D. Cohen and M.J. Ganley [Quart. J. Math. Oxford, 35 (1984) 101–113]

SIMULTANEOUS DETERMINATION OF METFORMIN, LINAGLIPTIN IN JENTADUETO AND METFORMIN, SAXAGLIPTIN IN KOMBIGLYZE BY LC-MS METHOD

Objective: The objective of the present investigation was to develop a novel, simple and economic method for the determination of metformin (MET), linagliptin (LIN) and saxagliptin (SAX) in jentadueto and kombiglyze sample by employing the liquid chromatography and mass spectrometric method for estimation in bulk and pharmaceutical dosage form in presence of degradation products.Methods: The chromatographic separation was achieved by using the mobile phase composition of methanol and ammonium acetate buffer pH 4.5 (85:15 % v/v) on the Hypurity advance C-18 column at a flow rate of 0.5 ml/min. Ion signals m/z 130.10/70.10, 473.10/420.40 and 316.30/180.20†for metformin, linagliptin and saxagliptin respectively measured in positive ion mode. The detailed validation of the method was performed as per ICH guidelines.Results: The results of all validation parameters found within acceptance limits. The linearity of the drugs was found to be in the concentration range of 50–5000 ng/ml for all the drugs. Accuracy of the drugs was found to be from 94-102% and precision was found 4.67% RSD for all three drugs. The validated method was employed for the determination of drugs in the formulation and also determined the drugs in the presence of degradation products under stress conditions.Conclusion: The method was developed and validated as per guidelines. Hence, this method can be used for the simultaneous determination of metformin, linagliptin and metformin, saxagliptin in bulk and combined dosage forms

Light Metal Matrix Composites - Present Status & Future Strategies

The unique tailorability of the composites to meet the required properties has made them as advanced engineering materials . The continuous fibre reinforced metal matrix composites were developed first . The high cost of the fibre as well as fabrication made them very expensive and hence they are used only in selected critical areas of aerospace and defence . The invention of synthesising discontinuous reinforced metal matrix composites by stir casting initiated in India in the early seventies 1 s a landmark in the history of Metal Matrix Composites (MMC). The initial feasibility studies on making the composites with variety of dispersoids for tailoring new materials possessing special properties with lower cost had kindled interest in many R&D and academic institutions in India in the eighties . Extensive R&D activities were witnessed during this period . The work carried out during this period can broadly be classified into processing methods . structure property correlation , specific property evaluation , prototype component development and evaluation , etc. The expected impact of composite as an exciting engineering material did not take place in the nineties.The industries are still not receptive and their response is lukewann . At present,only selective academic and R&D Institutions in India are pursuing MMC activity on a low profile . Eventhough similar trends in R&D were observed abroad in the developed countries wherein the industrial applications of composites specially in automotive and engineering industries is steadily increasing Indian industries are yet to think of using MMC components . This calls for a renewed concerted and sustaining effort,pooling up the resources and knowledge as well as consortium type approach among Indian R&D and Academic Institutions . The identified areas include generation of data bank on MMC and their properties. pilot plant production facility for demonstration of prototype developments under simulated industrial conditions , bringing down the cost by redesigning the components, etc

Recruitment of the Fouling Bivalve, Mytilopsis sallei (Recluz), on Metallic and Nonmetallic Surfaces at Visakhapatnam Harbor, India

In 1967, the dreissinid bivalve, Mytilopsis saUei (Recluz), was first noticed in Indian waters at the Southern Lighter Channel of Visakhapatnam harbor, Andhra Pradesh, India. It is believed that his species was introduced into the Indo-Pacific region from Central America via the Panama Canal and Fiji through ship foulin