655 research outputs found
Dimer Decimation and Intricately Nested Localized-Ballistic Phases of Kicked Harper
Dimer decimation scheme is introduced in order to study the kicked quantum
systems exhibiting localization transition. The tight-binding representation of
the model is mapped to a vectorized dimer where an asymptotic dissociation of
the dimer is shown to correspond to the vanishing of the transmission
coefficient thru the system. The method unveils an intricate nesting of
extended and localized phases in two-dimensional parameter space. In addition
to computing transport characteristics with extremely high precision, the
renormalization tools also provide a new method to compute quasienergy
spectrum.Comment: There are five postscript figures. Only half of the figure (3) is
shown to reduce file size. However, missing part is the mirror image of the
part show
Ordering of localized moments in Kondo lattice models
We describe the transition from a ferromagnetic phase, to a disordered para-
magnetic phase, which occurs in one-dimensional Kondo lattice models with
partial conduction band filling. The transition is the quantum order-disorder
transition of the transverse-field Ising chain, and reflects double-exchange
ordered regions of localized spins being gradually destroyed as the coupling to
the conduction electrons is reduced. For incommensurate conduction band
filling, the low-energy properties of the localized spins near the transition
are dominated by anomalous ordered (disordered) regions of localized spins
which survive into the paramagnetic (ferromagnetic) phase. Many interesting
properties follow, including a diverging susceptibility for a finite range of
couplings into the paramagnetic phase. Our critical line equation, together
with numerically determined transition points, are used to determine the range
of the double-exchange interaction. Models we consider are the spin 1/2 Kondo
lattices with antiferromagnetic (Kondo) coupling, with ferromagnetic (Hund's
rule) coupling, and the Kondo lattice with repulsive interactions between the
conduction electrons.Comment: 18 pages, 6 embedded eps figures. To appear in Phys Rev
Targeting therapy to the neuromuscular junction: Proof of concept
Introduction: The site of pathology in myasthenia gravis (MG) is the neuromuscular junction (NMJ). Our goal was to determine the ability to direct complement inhibition to the NMJ.
Methods: A single-chain antibody directed against the alpha subunit of the acetylcholine receptor was synthesized (scFv-35) and coupled to decay-accelerating factor (DAF, scFv-35-DAF). scFv-35-DAF was tested in a passive model of experimentally acquired MG.
Results: Administration of scFv-35-DAF to mice deficient in intrinsic complement inhibitors produced no weakness despite confirmation of its localization to the NMJ and no evidence of tissue destruction related to complement activation. Rats with experimentally acquired MG treated with scFV-35-DAF showed less weakness and a reduction of complement deposition.
Conclusions: We demonstrate a method to effectively target a therapeutic agent to the NMJ.
Muscle Nerve 49: 749–756, 201
Transport properties of one-dimensional interacting fermions in aperiodic potentials
Motivated by the existence of metal-insulator transition in one-dimensional
non-interacting fermions in quasiperiodic and pseudorandom potentials, we
studied interacting spinless fermion models using exact many-body Lanczos
diagonalization techniques. Our main focus was to understand the effect of the
fermion-fermion interaction on the transport properties of aperiodic systems.
We calculated the ground state energy and the Kohn charge stiffness Dc. Our
numerical results indicate that there exists a region in the interaction
strength parameter space where the system may behave differently from the
metallic and insulating phases. This intermediate phase may be characterized by
a power law scaling of the charge stiffness constant in contrast to the
localized phase where Dc scales exponentially with the size of the system.Comment: 11 pages LaTex document with 5 eps figures. Uses revtex style file
Phase transitions, entanglement and quantum noise interferometry in cold atoms
We show that entanglement monotones can characterize the pronounced
enhancement of entanglement at a quantum phase transition if they are sensitive
to long-range high order correlations. These monotones are found to develop a
sharp peak at the critical point and to exhibit universal scaling. We
demonstrate that similar features are shared by noise correlations and verify
that these experimentally accessible quantities indeed encode entanglement
information and probe separability.Comment: 4 pages 4 figure
Preparation of Single-Cell RNA-Seq Libraries for Next Generation Sequencing
For the past several decades, due to technical limitations, the field of transcriptomics has focused on population-level measurements that can mask significant differences between individual cells. With the advent of single-cell RNA-Seq, it is now possible to profile the responses of individual cells at unprecedented depth and thereby uncover, transcriptome-wide, the heterogeneity that exists within these populations. This unit describes a method that merges several important technologies to produce, in high-throughput, single-cell RNA-Seq libraries. Complementary DNA (cDNA) is made from full-length mRNA transcripts using a reverse transcriptase that has terminal transferase activity. This, when combined with a second “template-switch” primer, allows for cDNAs to be constructed that have two universal priming sequences. Following preamplification from these common sequences, Nextera XT is used to prepare a pool of 96 uniquely indexed samples ready for Illumina sequencing.National Institutes of Health (U.S.) (Centers of Excellence in Genomic Science 1P50HG006193-01)National Institutes of Health (U.S.) (Pioneer Award DP1OD003958-01)Broad Institute of MIT and HarvardHoward Hughes Medical InstituteKlarman Cell Observator
Orbital Configurations and Magnetic Properties of Double-Layered Antiferromagnet CsCuClBr
We report the single-crystal X-ray analysis and magnetic properties of a new
double-layered perovskite antiferromagnet, CsCuClBr. This
structure is composed of CuClBr double layers with elongated
CuClBr octahedra and is closely related to the SrTiO
structure. An as-grown crystal has a singlet ground state with a large
excitation gap of K, due to the strong
antiferromagnetic interaction between the two layers. CsCuClBr
undergoes a structural phase transition at K accompanied
by changes in the orbital configurations of Cu ions. Once a
CsCuClBr crystal is heated above , its magnetic
susceptibility obeys the Curie-Weiss law with decreasing temperature even below
and does not exhibit anomalies at . This implies that in
the heated crystal, the orbital state of the high-temperature phase remains
unchanged below , and thus, this orbital state is the metastable
state. The structural phase transition at is characterized as an
order-disorder transition of Cu orbitals.Comment: 6pages. 6figures, to appear in J. Phys. Soc. Jpn. Vol.76 No.
Early-stage compositional segregation in polymer-blend films
The existence of a transient period during the surface enrichment of a binary polymer blend by one of its components has been suggested by previous theoretical and experimental studies as well as computer simulations. Taking advantage of the high depth resolution of neutron reflectivity and the slow dynamics of polymers near their glass transition, we investigate this early-stage surface compositional enrichment in a phase separating polymer blend for the first time. Two stages of surface enrichment layer growth are observed. A rapid local surface enrichment at the chain segmental level occurs first, followed by a slower growth of a diffuse layer having a scale on the order of the bulk correlation length and the radius of gyration of the surface enriching polymer chains
Self-Similarity and Localization
The localized eigenstates of the Harper equation exhibit universal
self-similar fluctuations once the exponentially decaying part of a wave
function is factorized out. For a fixed quantum state, we show that the whole
localized phase is characterized by a single strong coupling fixed point of the
renormalization equations. This fixed point also describes the generalized
Harper model with next nearest neighbor interaction below a certain threshold.
Above the threshold, the fluctuations in the generalized Harper model are
described by a strange invariant set of the renormalization equations.Comment: 4 pages, RevTeX, 2 figures include
Fluid Flow Thermometry Using Thermographic Phosphors
Phosphor thermometry is a non-intrusive thermometry technique that allows for spatially and temporally resolved surface temperature measurements. The thermographic method has been employed in a number of applications that include combustion, sprays, and gas flows. In the current work, we investigate the implementation of thermographic phosphors in liquid flows, which is of interest in a wide range of applications in heat transfer, fluid mechanics, and thermal systems. Zinc oxide doped with Zinc (ZnO:Zn) was the phosphor employed for experimentation due to its high emission intensity and insolubility. In order to explore this application, the phosphor powder was uniformly dispersed in water using a magnetic stirring rod. The phosphor was excited by the third harmonic 355 nm output of a Nd:YAG laser, and the luminescence was examined using a fiber-coupled spectrometer. Analysis of the spectral data showed a significant redshift as the temperature approached boiling point. Further characterization of effects of temperature and experimental parameters such as ZnO:Zn concentration on the luminescence signal was performed
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