1,301 research outputs found
Carbohydrate Intake in Early Childhood and Body Composition and Metabolic Health: Results from the Generation R Study
High sugar intake in childhood has been linked to obesity. However, the role of
macronutrient substitutions and associations with metabolic health remain unclear. We examined
associations of carbohydrate intake and its subtypes with body composition and metabolic health
among 3573 children participating in a population-based cohort in the Netherlands. Intake of total
carbohydrate, monosaccharides and disaccharides, and polysaccharides at age 1 year was assessed
with a food-frequency questionnaire. We repeatedly measured childrenâs height and weight to
calculate BMI between their ages of 1 and 10 years. At ages 6 and 10 years, fat and fat-free mass
were measured with dual-energy X-ray-absorptiometry and blood concentrations of triglycerides,
cholesterol, and insulin were obtained. For all outcomes, we calculated age and sexspecific SD-scores.
In multivariable-adjusted linear mixed models, we found no associations of intake of carbohydrates
or its subtypes with childrenâs BMI or body composition. A higher intake of monosaccharides
and disaccharides was associated with higher triglyceride concentrations (0.02 SDS per 10 g/day,
95% CI: 0.01, 0.04). Higher monosaccharide and disaccharide intake was also associated with lower
HDL-cholesterol (â0.03 SDS, 95% CI: â0.04; â0.01), especially when it replaced polysaccharides.
Overall, our findings suggest associations of higher monosaccharide and disaccharide intake in early
childhood with higher triglyceride and lower HDL-choleste
Hydrothermal synthesis to water-stable luminescent carbon dots from acerola fruit for photoluminescent composites preparation and its application as sensors
Carbon dots (C-dots) possess the attractive properties of high stability, low toxicity, good water solubility, simple synthetic routes as well as size and excitation-dependent photoluminescence (PL).The aim of this work was to synthesize photoluminescent C-dots by hydrothermal method using acerola fruit (Malpighiaemarginata) as a row material, since this fruit contains large number of organic molecules. Studies about the optimal synthesis conditions were performed, where these organic molecules were converted into C-dots by hydrothermal carbonization at 180 ÂșC for 18 h. The C-dots exhibited a green emission light at 459 nm when excited under UV-light (λ ex= 370 nm). These nanomaterials were also successfully used to prepare C-dots/poly (vinyl alcohol) luminescent composites (C-dots/PVA). Both C-dots and C-dots/PVA composite films were investigated by using colorimetric visual sensor for Fe3+ metal ions detection. The results show that the prepared C-dots and C-dots/poly presented strong green emission light. The emission spectra of above materials were quenched in the presence of Fe3+ ions. Thus, highly specific âturn offâ fluorescence sensing of Fe3+ was achieved using fluorescent C-dots. Regarding, this work describe that the polymeric films as sensors of metallic ions in aqueous solution appears as a new perspectives to design new composite materials22
Rapid optimization of chromatography operating conditions using a nano- liter scale column on a microfluidic chip with integrated pneumatic valves and optical sensors
Purification of monoclonal antibodies (mAbs) is traditionally achieved by chromatographic separations, which are very robust but require time-consuming optimization on a case-by-case, particularly if a non-affinity step is used. In this context, multimodal chromatography has been explored as a versatile and cost-effective alternative to the established affinity step employed for capturing mAbs. However, selective capture/polishing of a target mAb using such multimodal ligands comes with the need for extensive and time-consuming optimization, due to the multitude of interactions that can be simultaneously promoted in the ligand. In this work, we developed a novel microfluidic platform comprising multimodal chromatography beads inside micro-columns for rapid screening of operating conditions. Sequential liquid insertion in the device was achieved by using integrated pneumatic valves and the chromatographic assays were combined with a signal acquisition module for on-chip fluorescence measurements.
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Thermodynamics of charged and rotating black strings
We study thermodynamics of cylindrically symmetric black holes. Uncharged as
well as charged and rotating objects have been discussed. We derive surface
gravity and hence the Hawking temperature and entropy for all these cases. We
correct some results in the literature and present new ones. It is seen that
thermodynamically these black configurations behave differently from
spherically symmetric objects
Magneto-optical trapping of bosonic and fermionic neon isotopes and their mixtures: isotope shift of the ^3P_2 to ^3D_3 transition and hyperfine constants of the ^3D_3 state of Ne-21
We have magneto-optically trapped all three stable neon isotopes, including
the rare Ne-21, and all two-isotope combinations. The atoms are prepared in the
metastable ^3P_2 state and manipulated via laser interaction on the ^3P_2 to
^3D_3} transition at 640.2nm. These cold (T = 1mK) and environmentally
decoupled atom samples present ideal objects for precision measurements and the
investigation of interactions between cold and ultracold metastable atoms. In
this work, we present accurate measurements of the isotope shift of the ^3P_2
to ^3D_3 transition and the hyperfine interaction constants of the ^3D_3 state
of Ne-21. The determined isotope shifts are (1625.9\pm0.15)MHz for Ne-20 to
Ne-22, (855.7\pm1.0)MHz for Ne-20 to Ne-21, and (770.3\pm1.0)MHz for Ne-21 to
Ne-22. The obtained magnetic dipole and electric quadrupole hyperfine
interaction constants are A(^3D_3)= (-142.4\pm0.2)MHz and
B(^3D_3)=(-107.7\pm1.1)MHz, respectively. All measurements give a reduction of
uncertainty by about one order of magnitude over previous measurements
Topological Charged Black Holes in High Dimensional Spacetimes and Their Formation from Gravitational Collapse of a Type II Fluid
Topological charged black holes coupled with a cosmological constant in
spacetimes are studied, where is an Einstein
space of the form . The global structure for
the four-dimensional spacetimes with is investigated systematically.
The most general solutions that represent a Type fluid in such a high
dimensional spacetime are found, and showed that topological charged black
holes can be formed from the gravitational collapse of such a fluid. When the
spacetime is (asymptotically) self-similar, the collapse always forms black
holes for , in contrast to the case , where it can form
either balck holes or naked singularities.Comment: 14 figures, to appear in Phys. Rev.
Spontaneous emission between an unusual pair of plates
We compute the modification in the spontaneous emission rate for a two-level
atom when it is located between two parallel plates of different nature: a
perfectly conducting plate and an infinitely permeable
one . We also discuss the case of two infinitely permeable
plates. We compare our results with those found in the literature for the case
of two perfectly conducting plates.Comment: latex file 4 pages, 4 figure
Limiting Carleman weights and anisotropic inverse problems
In this article we consider the anisotropic Calderon problem and related
inverse problems. The approach is based on limiting Carleman weights,
introduced in Kenig-Sjoestrand-Uhlmann (Ann. of Math. 2007) in the Euclidean
case. We characterize those Riemannian manifolds which admit limiting Carleman
weights, and give a complex geometrical optics construction for a class of such
manifolds. This is used to prove uniqueness results for anisotropic inverse
problems, via the attenuated geodesic X-ray transform. Earlier results in
dimension were restricted to real-analytic metrics.Comment: 58 page
Superconducting Transition Temperature in Heterogeneous Ferromagnet-Superconductor Systems
We study the shift of the the superconducting transition temperature in
ferromagnetic-superconducting bi-layers and in a superconducting film supplied
a square array of ferromagnetic dots. We find that the transition temperature
in these two cases change presumably in opposite direction and that its change
is not too small. We extend these results to multilayer structures. We predict
that rather small external magnetic field Oe can change the
transition temperature of the bilayer by 10% .Comment: 9 pages, 2 figure
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