2,642 research outputs found
O papel do designer gráfico na crescente standardização da indústria gráfica
Neste artigo abordamos os fatores que levaram à renovação do
oficio do designer gráfico, essencialmente no que diz respeito ao
desenvolvimento tecnológico das ferramentas que este profissional tem
ao seu dispor. Todo o sector da indústria gráfica – pré-impressão,
impressão e pós-impressão – sofreu grandes transformações
principalmente ao nÃvel tecnológico, organizacional e metodológico que
levam a que o designer gráfico tenha de se adaptar e desenvolver novas
valências que antes estavam entregues exclusivamente aos produtores
gráficos. Estas evoluções tecnológicas levaram a que o sector das artes
gráficas se transformasse progressivamente numa indústria gráfica, não
havendo espaço à experimentação, ao artesanal ou às metodologias
tentativa/erro anteriormente praticadas. Esta indústria acaba assim por
se regular através de normas internacionais que ditam quais os
parâmetros de qualidade a observar e de que forma estes podem ser
alcançados. Neste artigo serão assinaladas as novas relações entre os
diferentes atores do sector e qual o "novo" papel do designer gráfico
numa indústria cada vez mais standardizadaABSTRACT: This article deals with the issues that led to the renewal
graphic designer skills, mainly with regard to the technological
development of the tools that this professional has at its disposal. All the
graphic arts industry – pre-press, press and post-press – has changed
considerably mainly technological, organizational and methodological
level that lead graphic designer to adapt and develop new areas that
were delivered only to graphic producers. These technological
developments have led to the graphic arts sector gradually turn into a
printing industry, with no space for experimentation, to craft or use
attempt / error methodologies previously performed. This industry is now
regulated through international standards that order what quality
parameters should be observed and how these can be achieved. This
article inform the new relationships between the different players of the
sector and what the "new" graphic designer role in an increasingly
standardized industry.info:eu-repo/semantics/publishedVersio
Persistent varicella as the initial manifestation of systemic lymphoma
Varicella is a common benign childhood disease that often presents in adolescents and adults in a more severe form. We report a previously healthy 50-year-old man who developed multiple necrotic cutaneous ulcers associated with fever, asthenia and anorexia. Physical examination revealed few tense hemorrhagic vesicles on the trunk and necrotic cutaneous ulcers scattered over the entire cutaneous surface. After the diagnosis of varicella with varicella pneumonia was established, treatment with acyclovir was instituted. His poor response to treatment was indicative of immune compromise; an underlying peripheral T-cell lymphoma was discovered
Cutaneous manifestations of antiphospholipid syndrome: a review of the clinical features, diagnosis and management
Antiphospholipid syndrome is a relatively recent systemic autoimmune disorder defined by thrombotic events and/or obstetric complications in the presence of persistent elevated antiphospholipid antibodies. It is characterized by a wide spectrum of clinical presentations
and virtually any organ system or tissue may be affected by the consequences of vascular occlusion.
Diagnosis is sometimes difficult and although classification criteria have been published and revised there remain ongoing issues regarding nomenclature, expanding clinical features, laboratory tests and management and much still has to be done. Cutaneous manifestations are common and frequently the first sign of the disease. Although extremely diverse it’s important to know which dermatological findings should prompt consideration of antiphospholipid syndrome and the appropriate management for those patients. Much has
been debated about when to consider antiphospholipid syndrome and consensus still does not exist, however in spite of being a diagnostic challenge clinicians should know when to look for antiphospholipid antibodies since an early diagnosis is important to prevent further
and serious complications. In this article we focus on the cutaneous features that should raise suspicion on the presence of antiphospholipid syndrome and on the complex management of such patients. Many other dermatological signs related to this syndrome have been described in the literature but only occasionally and without consistency or statistic impact and therefore will not be considered hereO sÃndrome antifosfolipidico é uma patologia auto-imune relativamente recente definida por eventos trombóticos e/ou complicações obstétricas na presença de anticorpos antifosfolÃpido elevados persistentes. Caracteriza-se por um vasto leque de apresentações clÃnicas e virtualmente qualquer sistema orgânico ou tecido pode ser afectado por oclusão vascular. O diagnóstico é por vezes difÃcil e, apesar de critérios de classificação terem sido publicados e revistos, muitas dúvidas persistem relativamente à nomenclatura, caracterÃsticas clÃnicas, testes laboratoriais e abordagem destes doentes. As manifestações cutâneas são comuns e, frequentemente, o primeiro sinal da doença. Apesar da grande variabilidade, é importante reconhecer os achados dermatológicos que
devem levantar a suspeita de um sÃndrome antifosfolipidico, assim como a abordagem adequada destes doentes. Muito tem sido debatido sobre quando considerar o diagnóstico desta entidade, não havendo ainda consenso neste assunto; no entanto, apesar de ser um desafio diagnóstico, é importante saber quando investigar a presença de anticorpos antifosfolÃpidos, uma vez que um diagnóstico precoce é crucial para prevenir complicações
futuras graves. No presente artigo os autores descrevem as manifestações dermatológicas que devem fazer considerar o diagnóstico com enfoque na abordagem complexa destes doentes. Têm sido descritas na literatura muitas outras alterações cutâneas relacionadas
com esta entidade, no entanto, apenas de forma ocasional e sem consistência ou impacto estatÃstico, pelo que não serão consideradas
Late onset pityriasis rubra pilaris type IV treated with low-dose acitretin
Pityriasis rubra pilaris is a chronic inflammatory dermatosis of unknown etiology and great clinical variability. It has been divided into six categories. Types III, IV, and V occur in childhood and are distinguished by their clinical presentation, age of onset, and course. We report a 19-year-old male patient with a 2-week history of pruritic, scaling dermatosis of the hands, feet, elbows, and knees. He had no family history of skin disease. On physical examination, we observed circumscribed, reddish-orange, scaling plaques affecting the elbows and knees and a waxy palmoplantar keratoderma. The skin biopsy showed acanthosis, alternating orthokeratosis, parakeratosis, and follicular plugging suggestive of pityriasis rubra pilaris. The patient started treatment with oral acitretin, 25 mg every other day. The treatment was tolerated well, and after 6 months the lesions had resolved completely. Pityriasis rubra pilaris is a chronic papulosquamous disorder of unknown pathogenesis, characterized by reddish-orange scaly plaques, palmoplantar keratoderma, and keratotic follicular papules. There is still no consensus regarding the treatment, but therapeutic options include systemic retinoids, particularly acitretin in the recommended dose of 0.5 to 0.75 mg/kg/day. In our case, the patient was treated with a low-dose regimen of acitretin, which was effective and well tolerated.info:eu-repo/semantics/publishedVersio
Case for diagnosis
Abstract
We report a clinical case of a rare variant of pemphigus - pemphigus herpetiformis - which combines the clinical features of dermatitis herpetiformis with the immunological findings of pemphigus. Due to its atypical presentation, it is frequently misdiagnosed as dermatitis herpetiformis. It is basically characterized by the herpetiform pattern of skin lesions, severe pruritus and by the presence of eosinophilic spongiosis confirmed on histopathology. We call attention to the excellent response to dapsone
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Pyodermatitis vegetans of the vulva
Pyodermatitis vegetans (PV) is a rare inflammatory dermatosis of unknown etiology and difficult diagnosis characterized by vesiculopustular, exudative, and vegetating plaques usually localized in the axillary, genital, and oral region. It bears similarities to pemphigus vegetans but clinical history, histology, and immunofluorescence help confirm the diagnosis. Pyodermatitis vegetans is often associated with an underlying gastrointestinal disorder, especially ulcerative colitis. No standardized treatment plan is available for PV. Its evolution tends to follow the progression of the underlying disorder. We report a patient with vulvar PV with good response to systemic antibiotics and corticosteroids.info:eu-repo/semantics/publishedVersio
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