Contents of 1,4-Benzoxazin-3-ones and 2-Benzoxazolinone from Stenandrium dulce (Nees)

Marin, J.S. Instituto de Biologıa Vegetal y Biotecnologıa, Universidad de Talca, Casilla 747, Talca. ChileSecondary metabolites, DIBOA, HBOA, 7-OH-HBOA and BOA, were isolated and quantified from S. dulce (Nees), a native species in Chile belonging to the Acanthaceae family. The highest DIBOA and HBOA contents were determined in leaves (9.25 mmol kgÐ1 fr. wt) and root (6.81 mmol kgÐ1 fr. wt), respectively. Aglycones, 7-OH-HBOA and HBOA, were isolated together from root extracts of Acanthaceae species. Both, HBOA and 7-OH-HBOA should be direct precursors in the biosynthesis of DIBOA and DIMBOA, respectively

1,4-benzoxazin-3-one, 2-benzoxazolinone and gallic acid from Calceolaria thyrsilora Graham and their antibacterial activity

Secondary metabolites, DIBOA, HBOA, 7-OH-HBOA, BOA and gallic acid, were isolated and quantified from Calceolaria thyrsiflora Graham, a native medicinal plant of Chile belonging to the Scrophulariaceae family. The highest DIBOA contents were determined in leaves (145 mmol kg(-1) dry wt) and flowers (161 mmol kg(-1) dry wt). Antibacterial activities of DIBOA, HBOA, BOA, gallic acid and infusions of flowers and leaves were determined. The phytomedicinal properties attributed to C. thyrsiflora Graham could be understood on the basis of its antibacterial activit