Literary thoughts of H.A. Krishnapillai

In the 16th and 17th centuries A.D., Western Christianity came to Tamil Nadu along with the Western Europeans who came for trade. The Bible was first translated into Indian languages, and it was in Tamil that it was done by Ziegenbalg Iyer. Thus, as the Vedas spread all over the world, the people had a great deal of knowledge of the Scriptures, and since it was the time of European rule, the people had some knowledge of English. Pillai was also proficient in English. Therefore, he has not followed the Tamil tradition as it is, but has also incorporated the life of Europeans into his epic. Correctional Methods By the efforts of Christians, not only the Bible but also other literary texts were translated, so that the people had a wide range of knowledge of language and literature. His works are so good that he is praised as a Christian Kamban and a descendant of Veerama Munivar

Cardioprotective effect of pulicaria wightania against isoproterenol induced myocardial infarction in experimental rats

The current study was carried out to evaluate the cardio protective activity of Pulicaria Wightiana against Isoproterenol (ISO) induced myocardial infarction (MI). Pretreatment to the different groups were given for 30 days and ISO was administered at last two days with an interval of 24 hrs. Due to chronic ionotropy ISO induces MI. Blood was collected at the last day of experimental period and biomarkers were observed. The results indicate that the extract exhibited significant cardioprotective activity

International Nosocomial Infection Control Consortium report, data summary of 50 countries for 2010-2015: Device-associated module

•We report INICC device-associated module data of 50 countries from 2010-2015.•We collected prospective data from 861,284 patients in 703 ICUs for 3,506,562 days.•DA-HAI rates and bacterial resistance were higher in the INICC ICUs than in CDC-NHSN's.•Device utilization ratio in the INICC ICUs was similar to CDC-NHSN's. Background: We report the results of International Nosocomial Infection Control Consortium (INICC) surveillance study from January 2010-December 2015 in 703 intensive care units (ICUs) in Latin America, Europe, Eastern Mediterranean, Southeast Asia, and Western Pacific. Methods: During the 6-year study period, using Centers for Disease Control and Prevention National Healthcare Safety Network (CDC-NHSN) definitions for device-associated health care-associated infection (DA-HAI), we collected prospective data from 861,284 patients hospitalized in INICC hospital ICUs for an aggregate of 3,506,562 days. Results: Although device use in INICC ICUs was similar to that reported from CDC-NHSN ICUs, DA-HAI rates were higher in the INICC ICUs: in the INICC medical-surgical ICUs, the pooled rate of central line-associated bloodstream infection, 4.1 per 1,000 central line-days, was nearly 5-fold higher than the 0.8 per 1,000 central line-days reported from comparable US ICUs, the overall rate of ventilator-associated pneumonia was also higher, 13.1 versus 0.9 per 1,000 ventilator-days, as was the rate of catheter-associated urinary tract infection, 5.07 versus 1.7 per 1,000 catheter-days. From blood cultures samples, frequencies of resistance of Pseudomonas isolates to amikacin (29.87% vs 10%) and to imipenem (44.3% vs 26.1%), and of Klebsiella pneumoniae isolates to ceftazidime (73.2% vs 28.8%) and to imipenem (43.27% vs 12.8%) were also higher in the INICC ICUs compared with CDC-NHSN ICUs. Conclusions: Although DA-HAIs in INICC ICU patients continue to be higher than the rates reported in CDC-NSHN ICUs representing the developed world, we have observed a significant trend toward the reduction of DA-HAI rates in INICC ICUs as shown in each international report. It is INICC's main goal to continue facilitating education, training, and basic and cost-effective tools and resources, such as standardized forms and an online platform, to tackle this problem effectively and systematically