1,031 research outputs found
Plasticity and learning in a network of coupled phase oscillators
A generalized Kuramoto model of coupled phase oscillators with slowly varying
coupling matrix is studied. The dynamics of the coupling coefficients is driven
by the phase difference of pairs of oscillators in such a way that the coupling
strengthens for synchronized oscillators and weakens for non-synchronized
pairs. The system possesses a family of stable solutions corresponding to
synchronized clusters of different sizes. A particular cluster can be formed by
applying external driving at a given frequency to a group of oscillators. Once
established, the synchronized state is robust against noise and small
variations in natural frequencies. The phase differences between oscillators
within the synchronized cluster can be used for information storage and
retrieval.Comment: 10 page
Synchronization in a System of Globally Coupled Oscillators with Time Delay
We study the synchronization phenomena in a system of globally coupled
oscillators with time delay in the coupling. The self-consistency equations for
the order parameter are derived, which depend explicitly on the amount of
delay. Analysis of these equations reveals that the system in general exhibits
discontinuous transitions in addition to the usual continuous transition,
between the incoherent state and a multitude of coherent states with different
synchronization frequencies. In particular, the phase diagram is obtained on
the plane of the coupling strength and the delay time, and ubiquity of
multistability as well as suppression of the synchronization frequency is
manifested. Numerical simulations are also performed to give consistent
results
Regulation of ciliated cell differentiation in cultures of rat tracheal epithelial cells.
The cellular pathway of ciliated cell differentiation and its regulation is poorly defined. To begin to understand the process of ciliated cell differentiation, we sought to identify factors regulating ciliated cell development in vitro. Rat tracheal epithelial (RTE) cells were cultured on collagen gel-coated membranes at an air-liquid interface in hormone- and growth factor-supplemented medium (complete medium [CM]). Under these conditions, RTE cells first proliferate and then differentiate into a pseudostratified mucociliary epithelium. Ciliated cell differentiation was measured using a monoclonal antibody, RTE3, which was shown to specifically react with the plasma membrane of ciliated cells. Cultures were immunostained in situ, and the percentage of the culture surface covered with ciliated cells was estimated using videomicroscopy and an image analysis program. If an air-liquid interface was not created and the cells were maintained in the submerged state, ciliated cell differentiation was suppressed 25-fold. Culture in the absence of mitogenic components present in CM, including epidermal growth factor (EGF), cholera toxin (CT), or bovine pituitary extract, resulted in 2- to 4-fold increases in the percentage of ciliated cells. When both EGF and CT were removed from the media, DNA synthesis and total cell number was reduced, while ciliated cell differentiation increased as much as 5-fold. These results demonstrate that submersion inhibits, while withdrawal of mitogenic compounds promotes, ciliated cell differentiation in vitro
Quantum Coherence in a Single Ion due to strong Excitation of a metastable Transition
We consider pump-probe spectroscopy of a single ion with a highly metastable
(probe) clock transition which is monitored by using the quantum jump
technique. For a weak clock laser we obtain the well known Autler-Townes
splitting. For stronger powers of the clock laser we demonstrate the transition
to a new regime. The two regimes are distinguished by the transition of two
complex eigenvalues to purely imaginary ones which can be very different in
magnitude. The transition is controlled by the power of the clock laser. For
pump on resonance we present simple analytical expressions for various
linewidths and line positions.Comment: 6 figures. accepted for publication in PR
Collective behavior of "electronic fireflies"
A simple system composed of electronic oscillators capable of emitting and
detecting light-pulses is studied. The oscillators are biologically inspired,
their behavior is designed for keeping a desired light intensity, W, in the
system. From another perspective, the system behaves like modified integrate
and fire type neurons that are pulse-coupled with inhibitory type interactions:
the firing of one oscillator delays the firing of all the others. Experimental
and computational studies reveal that although no driving force favoring
synchronization is considered, for a given interval of W phase-locking appears.
This weak synchronization is sometimes accompanied by complex dynamical
patterns in the flashing sequence of the oscillators.Comment: 4 pages, 4 figures include
Associated production of charged Higgs bosons and top quarks with POWHEG
The associated production of charged Higgs bosons and top quarks at hadron
colliders is an important discovery channel to establish the existence of a
non-minimal Higgs sector. Here, we present details of a next-to-leading order
(NLO) calculation of this process using the Catani-Seymour dipole formalism and
describe its implementation in POWHEG, which allows to match NLO calculations
to parton showers. Numerical predictions are presented using the PYTHIA parton
shower and are compared to those obtained previously at fixed order, to a
leading order calculation matched to the PYTHIA parton shower, and to a
different NLO calculation matched to the HERWIG parton shower with MC@NLO. We
also present numerical predictions and theoretical uncertainties for various
Two Higgs Doublet Models at the Tevatron and LHC.Comment: 36 page
Synchronization and resonance in a driven system of coupled oscillators
We study the noise effects in a driven system of globally coupled
oscillators, with particular attention to the interplay between driving and
noise. The self-consistency equation for the order parameter, which measures
the collective synchronization of the system, is derived; it is found that the
total order parameter decreases monotonically with noise, indicating overall
suppression of synchronization. Still, for large coupling strengths, there
exists an optimal noise level at which the periodic (ac) component of the order
parameter reaches its maximum. The response of the phase velocity is also
examined and found to display resonance behavior.Comment: 17 pages, 3 figure
Phase synchronization and noise-induced resonance in systems of coupled oscillators
We study synchronization and noise-induced resonance phenomena in systems of
globally coupled oscillators, each possessing finite inertia. The behavior of
the order parameter, which measures collective synchronization of the system,
is investigated as the noise level and the coupling strength are varied, and
hysteretic behavior is manifested. The power spectrum of the phase velocity is
also examined and the quality factor as well as the response function is
obtained to reveal noise-induced resonance behavior.Comment: to be published in Phys. Rev.
Meson screening masses from lattice QCD with two light and the strange quark
We present results for screening masses of mesons built from light and
strange quarks in the temperature range of approximately between 140 MeV to 800
MeV. The lattice computations were performed with 2+1 dynamical light and
strange flavors of improved (p4) staggered fermions along a line of constant
physics defined by a pion mass of about 220 MeV and a kaon mass of 500 MeV. The
lattices had temporal extents Nt = 4, 6 and 8 and aspect ratios of Ns / Nt \geq
4. At least up to a temperature of 140 MeV the pseudo-scalar screening mass
remains almost equal to the corresponding zero temperature pseudo-scalar (pole)
mass. At temperatures around 3Tc (Tc being the transition temperature) the
continuum extrapolated pseudo-scalar screening mass approaches very close to
the free continuum result of 2 \pi T from below. On the other hand, at high
temperatures the vector screening mass turns out to be larger than the free
continuum value of 2 \pi T. The pseudo-scalar and the vector screening masses
do not become degenerate even for a temperature as high as 4Tc. Using these
mesonic spatial correlation functions we have also investigated the restoration
of chiral symmetry and the effective restoration of the axial symmetry. We have
found that the vector and the axial-vector screening correlators become
degenerate, indicating chiral symmetry restoration, at a temperature which is
consistent with the QCD transition temperature obtained in previous studies. On
the other hand, the pseudo-scalar and the scalar screening correlators become
degenerate only at temperatures larger than 1.3Tc, indicating that the
effective restoration of the axial symmetry takes place at a temperature larger
than the QCD transition temperature.Comment: Published versio
Injection site vaccinology of a recombinant vaccinia-based vector reveals diverse innate immune signatures
Poxvirus systems have been extensively used as vaccine vectors. Herein a RNA-Seq analysis of intramuscular injection sites provided detailed insights into host innate immune responses, as well as expression of vector and recombinant immunogen genes, after vaccination with a new multiplication defective, vaccinia-based vector, Sementis Copenhagen Vector. Chikungunya and Zika virus immunogen mRNA and protein expression was associated with necrosing skeletal muscle cells surrounded by mixed cellular infiltrates. The multiple adjuvant signatures at 12 hours post-vaccination were dominated by TLR3, 4 and 9, STING, MAVS, PKR and the inflammasome. Th1 cytokine signatures were dominated by IFNγ, TNF and IL1β, and chemokine signatures by CCL5 and CXCL12. Multiple signatures associated with dendritic cell stimulation were evident. By day seven, vaccine transcripts were absent, and cell death, neutrophil, macrophage and inflammation annotations had abated. No compelling arthritis signatures were identified. Such injection site vaccinology approaches should inform refinements in poxvirus-based vector design.Jessamine E. Hazlewood, Troy Dumenil, Thuy T. Le, Andrii Slonchak, Stephen H. Kazakoff, Ann-Marie Patch ... et al
- …