115 research outputs found

    The Effect of the Marketing Mix and Specialized Knowledge on the Export Performance of SMEs Exporting Dry Fruits

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    Export is a crucial driver of economic growth in various countries and significantly contributes to a country's entry into global markets and enhances economic success. In developing countries such as Iran, economic and social development programs prioritize the expansion of exports, particularly high value added agricultural products. The growth in non-oil exports, such as dried fruits, and the entry of domestic producers into new global markets have led to an increased demand for Iran's export products. This has also resulted in higher production levels, increased employment opportunities, and higher value added in the related activities. To enhance export performance, which is a crucial measure of a company's success in utilizing its resources and capabilities in the international arena over a specific period of time, it is important to focus on improving marketing strategies and specialized knowledge. Therefore, this research aims to examine the impact of marketing mix and specialized marketing knowledge on the export performance of small and medium-sized enterprises (SMEs) involved in exporting dried fruits in Mashhad, Iran in 2022. A total of 80 questionnaires were distributed among senior managers, board members, and business managers of dried fruits SMEs using the available sampling method. Structural equation modeling was employed for data analysis and test of research hypotheses. The statistical data and structural equation modeling revealed that the joint impact of marketing mix and specialized marketing knowledge has a positive and significant influence on export performance. In order to improve the company's profitability, it is essential for senior managers and sales managers to recognize the significance of these two factors and undergo relevant training to acquire the necessary skills. Moreover, managers should make effective use of appropriate distribution channels to expand their exports. Simultaneously, they should consider adapting product quality and packaging to align with the preferences of foreign buyers

    First record of the seed-eating wasp, Systole eremodauci (Hym.: Eurytomidae) from Iran

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    The family Eurytomidae includes economically important wasps, which feed on the seeds of various agricultural, horticultural and rangeland plants. This report is part of a survey conducted during 2009-2012 to identify the seed-eating pests of non-legume rangeland plants in the Fars province of Iran. The eurytomid species Systole eremodauci Zerova, 1994 was collected on ammoniacum plant, Dorema ammoniacum (D. Don.), and is first recorded from Iran

    Basic effects of pulp refining on fiber properties- a review

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    The requirement for high quality pulps which are widely used in paper industries has increased the demand for pulp refining (beating) process. Pulp refining is a promising approach to improve the pulp quality by changing the fiber characteristics. The diversity of research on the effect of refining on fiber properties which is due to the different pulp sources, pulp consistency and refining equipment has interested us to provide a review on the studies over the last decade. In this article, the influence of pulp refining on structural properties i.e., fibrillations, fine formation, fiber length, fiber curl, crystallinity and distribution of surface chemical compositions is reviewed. The effect of pulp refining on electrokinetic properties of fiber e. g., surface and total charges of pulps is discussed. In addition, an overview of different refining theories, refiners as well as some tests for assessing the pulp refining is presented. (C) 2014 Elsevier Ltd. All rights reserved

    Distribution and New Host Plants of Seed Beetles (Col.: Chrysomelidae: Bruchinae) from Iran

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    This report is part of a national project for gathering and classifying the arthropod seed feeders in different provinces of Iran between 2008–2014. In this paper, nineteen host species with their areas of distribution are presented for twelve species of seed beetles (Chrysomelidae: Bruchinae). Most of the identified host plants (84%) belong to the family Fabaceae (Leguminosae). In addition, all known hosts for these beetles are discussed. The identified species in this study were confirmed by Dr. Alex Delobel in the Natural history Museum of Paris. The studied material is deposited in the arthropod collection of Research Institute of Forests and Rangelands

    ROCK1 and LIMK2 Interact in Spread but Not Blebbing Cancer Cells

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    Cancer cells migrating within a 3D microenvironment are able to adopt either a mesenchymal or amoeboid mode of migration. Amoeboid migration is characterised by membrane blebbing that is dependent on the Rho effectors, ROCK1/2. We identify LIMK2 as the preferred substrate for ROCK1 but find that LIMK2 did not induce membrane blebbing, suggesting that a LIMK2 pathway is not involved in amoeboid-mode migration. In support of this hypothesis, novel FRET data demonstrate a direct interaction between ROCK1 and LIMK2 in polarised but not blebbing cells. Our results point to a specific role for the ROCK1:LIMK2 pathway in mesenchymal-mode migration

    Tychiini and Mecinini (Coleoptera: Curculionidae, Curculioninae) of Iran: eleven species recorded for the first time, with new data on host plants and distribution of several species

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    A faunistic study on the tribes Tychiini and Mecinini (Curculionidae, Curculioninae) was carried out during the years 2010-2013 in different ecological regions of Iran. Twenty nine species belonging to the genera Mecinus Germar, 1821, Gymnetron Schoenherr, 1825, Rhinusa Stephens, 1829, Cleopomiarus Pierce, 1919, Tychius Germar, 1817 and Sibinia Germar, 1817 were collected. Localities and ecological notes on each species are provided. Among these, The following 11 species are new to the Iranian fauna: Mecinus crassifemur (Arzanov, 1991), Mecinus simus (Mulsant & Rey, 1859), Gymnetron linkei Reitter, 1907, Rhinusa antirrhini (Paykull, 1800), Rhinusa brondelii (H. Brisout de Barneville, 1862), Rhinusa florum (Rübsaamen, 1895), Tychius reitteri Faust, 1889, Tychius tridentinus Penecke, 1922, Sibinia aureofulva (Desbrochers des Loges, 1875), Sibinia pellucens (Scopoli, 1772), Sibinia unicolor Fảhraeus, 1843, whereas all other 18 species are new for one or more provinces. Host plants of several species reported for the first time and commented as well

    Etk/Bmx Regulates Proteinase-Activated-Receptor1 (PAR1) in Breast Cancer Invasion: Signaling Partners, Hierarchy and Physiological Significance

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    BACKGROUND: While protease-activated-receptor 1 (PAR(1)) plays a central role in tumor progression, little is known about the cell signaling involved. METHODOLOGY/PRINCIPAL FINDINGS: We show here the impact of PAR(1) cellular activities using both an orthotopic mouse mammary xenograft and a colorectal-liver metastasis model in vivo, with biochemical analyses in vitro. Large and highly vascularized tumors were generated by cells over-expressing wt hPar1, Y397Z hPar1, with persistent signaling, or Y381A hPar1 mutant constructs. In contrast, cells over-expressing the truncated form of hPar1, which lacks the cytoplasmic tail, developed small or no tumors, similar to cells expressing empty vector or control untreated cells. Antibody array membranes revealed essential hPar1 partners including Etk/Bmx and Shc. PAR(1) activation induces Etk/Bmx and Shc binding to the receptor C-tail to form a complex. Y/A mutations in the PAR(1) C-tail did not prevent Shc-PAR(1) association, but enhanced the number of liver metastases compared with the already increased metastases obtained with wt hPar1. We found that Etk/Bmx first binds via the PH domain to a region of seven residues, located between C378-S384 in PAR(1) C-tail, enabling subsequent Shc association. Importantly, expression of the hPar1-7A mutant form (substituted A, residues 378-384), which is incapable of binding Etk/Bmx, resulted in inhibition of invasion through Matrigel-coated membranes. Similarly, knocking down Etk/Bmx inhibited PAR(1)-induced MDA-MB-435 cell migration. In addition, intact spheroid morphogenesis of MCF10A cells is markedly disrupted by the ectopic expression of wt hPar1. In contrast, the forced expression of the hPar1-7A mutant results in normal ball-shaped spheroids. Thus, by preventing binding of Etk/Bmx to PAR(1) -C-tail, hPar1 oncogenic properties are abrogated. CONCLUSIONS/SIGNIFICANCE: This is the first demonstration that a cytoplasmic portion of the PAR(1) C-tail functions as a scaffold site. We identify here essential signaling partners, determine the hierarchy of binding and provide a platform for therapeutic vehicles via definition of the critical PAR(1)-associating region in the breast cancer signaling niche
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