Analytic regularity for a singularly perturbed system of reaction-diffusion equations with multiple scales: proofs

We consider a coupled system of two singularly perturbed reaction-diffusion equations, with two small parameters $0< \epsilon \le \mu \le 1$, each multiplying the highest derivative in the equations. The presence of these parameters causes the solution(s) to have \emph{boundary layers} which overlap and interact, based on the relative size of $\epsilon$ and $$. We construct full asymptotic expansions together with error bounds that cover the complete range $0 < \epsilon \leq \mu \leq 1$. For the present case of analytic input data, we derive derivative growth estimates for the terms of the asymptotic expansion that are explicit in the perturbation parameters and the expansion order

An evaluation of low volume high-intensity intermittent training (HIIT) for health risk reduction in overweight and obese men

Abstract ᅟ Both sprint interval training (SIT) and high-intensity intermittent training (HIIT) have been described as time-efficient strategies for inducing favourable metabolic and cardiorespiratory adaptations in healthy and diseased participants. Background To date, little attention has been given to profiling the potential health benefits of HIIT or modified HIIT training within overweight and obese cohorts with particular focus on inflammation. Within this pilot trial, we tested the hypothesis that 6 sessions of HIIT performed over 2 weeks with 1–2 days’ rest would improve aerobic capacity, glucose metabolism and inflammatory profile in an overweight and obese male cohort. Additionally, we profiled the potential health benefits of 4 HIIT sessions performed over the same period. Methods 18 overweight or obese males (BMI = 31.2 ± 3.6; V̇O2 = 30.3 ± 4.4 ml.kg.min-1) were studied before and 72 h after HIIT. Training sessions consisted of 10 x 1 min intervals at 90% HRpeak separated by 1 min recovery periods. Exercise was performed either 6 (group 1, n = 8) or 4 (group 2, n = 10) times over a 2 week period. Results After training no changes were detected from baseline for body composition, aerobic capacity, glucose metabolism or inflammatory profile (p > 0.05) in either group. Conclusion Both 6 and 4 sessions of HIIT performed over a 2-week period are ineffective in improving selected health markers within an overweight and obese cohort. Trial registration This trial reports data from human participants and was retrospectively registered on 22/02/2017 with the ISRCTN registry, trial number ISRCTN90672085

Reducing the Read Noise of HAWAII-2RG Detector Systems with Improved Reference Sampling and Subtraction (IRS2)

IRS2 is a Wiener-optimal approach to using all of the reference information that Teledyne's HAWAII-2RG detector arrays provide. Using a new readout pattern, IRS2 regularly interleaves reference pixels with the normal pixels during readout. This differs from conventional clocking, in which the reference pixels are read out infrequently, and only in a few rows and columns around the outside edges of the detector array. During calibration, the data are processed in Fourier space, which is <;:lose to the noise's eigenspace. Using IRS2, we have reduced the read noise of the James Webb Space Telescope Near Infrared Spectrograph by 15% compared to conventional readout. We are attempting to achieve further gains by calibrating out recently recognized non-stationary noise that appears at the frame rate

Principal Components Analysis of a JWST NIRSpec Detector Subsystem

We present principal component analysis (PCA) of a flight-representative James Webb Space Telescope NearInfrared Spectrograph (NIRSpec) Detector Subsystem. Although our results are specific to NIRSpec and its T - 40 K SIDECAR ASICs and 5 m cutoff H2RG detector arrays, the underlying technical approach is more general. We describe how we measured the systems response to small environmental perturbations by modulating a set of bias voltages and temperature. We used this information to compute the systems principal noise components. Together with information from the astronomical scene, we show how the zeroth principal component can be used to calibrate out the effects of small thermal and electrical instabilities to produce cosmetically cleaner images with significantly less correlated noise. Alternatively, if one were designing a new instrument, one could use a similar PCA approach to inform a set of environmental requirements (temperature stability, electrical stability, etc.) that enabled the planned instrument to meet performance requirement

Low HDL Cholesterol, Smoking and IL-13 R130Q Polymorphism are Associated with Myocardial Infarction in Greek Cypriot Males. A Pilot Study

This study was carried out in Greek Cypriot males to identify risk factors that predispose to myocardial infarction (MI). Genetic and lipid risk factors were investigated for the first time in a Greek Cypriot male case-control study.Contrary to other studies, mean low density lipoprotein cholesterol did not differ between cases and controls. High density lipoprotein cholesterol on the other hand, although within normal range in cases and controls, was significantly higher in the control population. In agreement with many other studies, smoking was significantly more prevalent in cases compared with controls. In pooled cases and controls, smokers had a significantly lower HDL-C level compared with non-smokers. The frequency of the IL-13 R130Q homozygotes for the mutation (QQ), as well as the mutant allele were significantly higher in cases compared with controls. The IL-13 R130Q variant, or another locus, linked to it, may increase the risk of MI

Special Issue: "Other Psychotherapies” – Healing Interactions Across Time, Geography and Culture [Guest Editors]

No abstract available

Structure of a fossil ridge-transform intersection in the troodos ophiolite

RECENT palaeomagnetic studies of sheeted dykes adjacent to the east-west trending Southern Troodos transform fault of Cyprus have demonstrated significant clockwise block rotations, which are most easily interpreted as being due to drag induced by dextral strike-slip faulting along the transform1–6. We show here that such rotations have not occurred along the entire length of the transform; instead, to the west of the areas previously studied the sheeted dykes have been subjected to simple tilting only, indicating normal faulting but no strike slip. The changeover between these two domains of differing structural styles, near the village of Mandria, is approximately in line with the centre of the Solea graben, a north–south trending structure within the Troodos massif which has previously been interpreted as a fossil ridge axis7. We suggest that the Mandria area represents a fossilized ridge–transform intersection, and present the results of a detailed field investigation of the area, together with preliminary palaeomagnetic data, to determine the relationship between tectonism and magmatism at such plate boundary zones. We use our findings to test a recent theoretical model8 of deformation processes at ridge-transform intersections, and show that distributed deformation due to block rotation is largely confined to the ridge–transform corner itself