Impacts of Protected Areas on Local Livelihoods in Cambodia

SummaryImpact evaluation methods (mixed effects models and matching) were used to investigate the effect of protected areas (PAs) on poverty and livelihoods in Cambodia, comparing households inside PAs with bordering villages and controls. There was no evidence that PAs exacerbated local poverty or reduce agricultural harvests in comparison with controls. Households bordering the PAs were significantly better off due to greater access to markets and services. Non-timber forest product (NTFP) collectors inside PAs were significantly better off than controls and had greater rice harvests, because they had more secure access to land and forest resources. The PAs in Cambodia therefore have some positive impacts on households that use forest and land resources for their livelihoods

Exact norm-conserving stochastic time-dependent Hartree-Fock

We derive an exact single-body decomposition of the time-dependent Schroedinger equation for N pairwise-interacting fermions. Each fermion obeys a stochastic time-dependent norm-preserving wave equation. As a first test of the method we calculate the low energy spectrum of Helium. An extension of the method to bosons is outlined.Comment: 21 pages, 3 figures, LaTeX fil

What's behind the NEWS? National Early Warning Scores in primary care

Everyone is talking about the NEWS — National Early Warning Scores.1 GPs will have noticed that ambulance call handlers are now routinely asking health professionals for a patient’s NEWS,2 and some areas are encouraging routine use of this scoring system in the community.3 So why has this happened and what is the evidence to support its use in the community? Should GPs be adopting NEWS or NEWS2 (an updated version that puts a greater emphasis on new onset confusion and recognises alternative oxygen saturations for people with respiratory failure) as part of their usual practice? Early warning scores (EWS), most recently NEWS2, have been used in hospitals for several years. In secondary care settings, they are primarily used by members of the team recording routine physiological observations in order to identify patients who are deteriorating clinically. The universal use of a common scoring system allows clinical information to be communicated efficiently across departments, clinical settings, and between clinical colleagues. Its usefulness as a common language, combined with the drive to identify sepsis early, have contributed to the widespread adoption and acceptance of NEWS2 in secondary care

The effect of audio cues and sound source stimuli on the perception of approaching objects

Objects that move in depth on an approaching trajectory (looming) are often encountered in both the real and virtual worlds. Examples include navigating oncoming traffic, and sporting and gaming activities where judgements are made to avoid or attack approaching objects. How people react to looming objects may impact on their survival and progression in the real, virtual, and gaming worlds, and relies on a person’s ability to precisely interpret movement and depth cues. Psychological studies investigating auditory looming often depict an object’s movement using simple audio cues (primarily amplitude increase) which are applied to tones (often sine or triangle waves) which are not normally encountered in the natural world. Whilst these studies provide valuable information about human perception and responses, technological advances allow us to present complex auditory stimuli with a range of audio cues and real-world sound sources, and to collect measurements on human perception and responses to ecologically valid stimuli

Comparative evaluation of pressure distribution between horizontal and vertical wells in a reservoir (edge water drive)

This paper presents comparative analysis between the pressure behavior of a horizontal well and a vertical well both subject to edge water drive. Green and source function were used to evaluate the performance of horizontal well and vertical well, eventually, compared based dimensionless pressures and pressure derivatives computed by varying the reservoir geometry. Results presented as type curves show that the rate of decline of the pressure derivative curve is more sharper and sensitive in vertical well than horizontal well of the same geometry indicating a shorter period of clean oil production in vertical well than the horizontal well. The period of radial flow as shown by the horizontal flattened part of the type curve indicate that for all reservoir geometry, the horizontal well will be able to sustain longer period of the radial flow than vertical well given infinite conductivity condition.Keywords: dimensionless pressure, dimensionless pressure derivative, horizontal well, vertical well, edge water drive, radial flo

The birth memories and recall questionnaire (BirthMARQ): development and evaluation

Background: Childbirth is a challenging and emotive experience that is accompanied by strong positive and/or negative emotions. Memories of birth may be associated with how women cognitively process birth events postpartum and potentially their adaptation to parenthood. Characteristics of memories for birth may also be associated with postnatal psychological wellbeing. This paper reports the development and evaluation of a questionnaire to measure characteristics of memories of childbirth and to examine the relationship between memories for birth and mental health. Methods: The Birth Memories and Recall Questionnaire (BirthMARQ) was developed by generating items from literature reviews and general measures of memory characteristics to cover dimensions relevant to childbirth. Fifty nine items were administered to 523 women in the first year after childbirth (M = 23.7 weeks) as part of an online study of childbirth. Validity of the final scale was checked by examining differences between women with and without probable depression and PTSD. Results: Principal components analysis identified 23 items representing six aspects of memory accounting for 64% of the variance. These were: Emotional memory, Centrality of memory to identity, Coherence, Reliving, Involuntary recall, and Sensory memory. Reliability was good (M alpha = .80). Women with probable depression or PTSD reported more emotional memory, centrality of memories and involuntary recall. Women with probable depression also reported more reliving, and those with probable PTSD reported less coherence and sensory memory. Conclusion: The results suggest the BirthMARQ is a coherent and valid measure of the characteristics of memory for childbirth which may be important in postnatal mood and psychopathology. While further testing of its reliability and validity is needed, it is a measure capable of becoming a valuable tool for examining memory characteristics in the important context of childbirth

Analysis of tick-borne encephalitis virus-induced host responses in human cells of neuronal origin and interferon-mediated protection

Tick-borne encephalitis virus (TBEV) is a member of the genus Flavivirus. It can cause serious infections in humans that may result in encephalitis/meningoencephalitis. Although several studies have described the involvement of specific genes in the host response to TBEV infection in the central nervous system (CNS), the overall network remains poorly characterized. Therefore, we investigated the response of DAOY cells (human medulloblastoma cells derived from cerebellar neurons) to TBEV (Neudoerfl strain, Western subtype) infection to characterize differentially expressed genes by transcriptome analysis. Our results revealed a wide panel of interferon-stimulated genes (ISGs) and pro-inflammatory cytokines, including type III but not type I (or II) interferons (IFNs), which are activated upon TBEV infection, as well as a number of non-coding RNAs, including long non-coding RNAs. To obtain a broader view of the pathways responsible for eliciting an antiviral state in DAOY cells we examined the effect of type I and III IFNs and found that only type I IFN pre-treatment inhibited TBEV production. The cellular response to TBEV showed only partial overlap with gene expression changes induced by IFN-β treatment – suggesting a virus-specific signature – and we identified a group of ISGs that were highly up-regulated following IFN-β treatment. Moreover, a high rate of down-regulation was observed for a wide panel of pro-inflammatory cytokines upon IFN-β treatment. These data can serve as the basis for further studies of host–TBEV interactions and the identification of ISGs and/or lncRNAs with potent antiviral effects in cases of TBEV infection in human neuronal cells

Corrigendum: Analysis of tick-borne encephalitis virus-induced host responses in human cells of neuronal origin and interferon-mediated protection

No abstract available

Genome sequence of canine herpesvirus

Canine herpesvirus is a widespread alphaherpesvirus that causes a fatal haemorrhagic disease of neonatal puppies. We have used high-throughput methods to determine the genome sequences of three viral strains (0194, V777 and V1154) isolated in the United Kingdom between 1985 and 2000. The sequences are very closely related to each other. The canine herpesvirus genome is estimated to be 125 kbp in size and consists of a unique long sequence (97.5 kbp) and a unique short sequence (7.7 kbp) that are each flanked by terminal and internal inverted repeats (38 bp and 10.0 kbp, respectively). The overall nucleotide composition is 31.6% G+C, which is the lowest among the completely sequenced alphaherpesviruses. The genome contains 76 open reading frames predicted to encode functional proteins, all of which have counterparts in other alphaherpesviruses. The availability of the sequences will facilitate future research on the diagnosis and treatment of canine herpesvirus-associated disease