Influence of Wet Heat Treatment on the Performance Properties of Fabrics of Different Fibrous Composition

The article deals with the issues of changing the qualitative characteristics of dress fabrics under the influence of wet-heat returns. For the study, the fabrics in question were washed (the number of washes was 1, 5, 10). A comprehensive analysis of the results of testing dress fabrics for options before washing and after washing was carried out

Assessment of the physical development and metabolic status of children born to women with gestational diabetes

Backgraund: Gestational diabetes mellitus (GDM) is one of the most common metabolic disorders found during pregnancy. Currently, it is relevant not only to search optimal target levels of glycemia during pregnancy, but also to study the ­effect of different glycemia levels on fetal development and further changes in glucose and lipid metabolism in children.Aims: To describe perinatal period, physical development and metabolic status of children born to women with GDM and different glucose levels during pregnancy.Materials and methods: The perinatal period features and anthropometric parameters at birth were evaluated in 300 children born to women with GDM and different levels of glycemia during pregnancy. Over the course two years, 141 children have been evaluated for physical development parameters and glucose and lipid metabolism. Fasting and postprandial glycemia was measured with glucometer for 14 days in 33 children aged 1 to 4 years.Results: The anthropometric parameters of children at birth did not differ from the parameters of the control group (p> 0.05) when during pregnancy fasting blood glucose was less than 5.1 mmol / l and 7.0 mmol / l 1 hour after a meal. The glycemia in women above this level was associated with an increase of frequency and risk of a body mass index, body mass / length ratio and head circumference “above average” in children at birth (p <0.05). With the dynamic control of anthropometric parameters up to 2 years, no differences between the comparison groups were obtained (p> 0.05). The change in metabolic parameters was represented by neonatal hypoglycemia in children of GDM group (GDM group — 23%, control group — 3.5%, p = 0.000002), the least risk of which occurred in group with the lowest fasting and postprandial glycemic values during pregnancy. Fasting glucose, and insulin levels, НOMA index, triglycerides and cholesterol, as well as monitoring fasting and postprandial glycemia for 14 days, were obtained no significant differences between the comparison groups of children (p> 0.05).Conclusions: The lowest risks of neonatal hypoglycemia and anthropometric deviations at birth were associated with the lowest glycemia levels during pregnancy, which correspond to the criteria of the Russian clinical guidelines

Great patriotic war 1941-1945 as historical memory phenomenon of contemporary Russian students

The paper presents the results of a Russian study on the state and dynamics of the historical memory of Russian students. As a scientific result, the paper presents the main socialization results by virtue of broadcasting the historical memory of the Great Patriotic War to students of the Russian frontier regio

Influence of the Structure of Heavy Oil Disperse System on its Rheological Properties Under Steam-Heat Treatment Conditions

© 2017, Springer Science+Business Media, LLC, part of Springer Nature. The distinctive features of the structure and composition of hydrocarbon disperse systems in various types of heavy oils after steam-heat treatment, including use of low-boiling hydrocarbons, are determined. Methodological approaches are developed to determine the stability of heavy hydrocarbon resources as a function of composition and structure of the hydrocarbon disperse systems. Based on theoretical concepts of oil disperse systems, the composition of the latter is characterized quantitatively. A notable feature of low-viscosity oils is greater affinity of the components of the solvate shell and the dispersion medium. As a result, the dispersion medium participates in cross-linking of the oil disperse system significantly, which leads to a decrease in the dispersivity of the system and in its viscosity

The development of liquid dosage forms on the basis of curry leaves to prevent and control the level of glucose in the blood

The article considers the development of technology of production of alcohol tincture based on curry leaves. The optimal parameters of the production of alcohol tincture: the ratio of alcohol 70% / Curry leaves 5/1, the absorption coefficient 1,3, the duration of 7 days.В статье рассмотрена разработка технологии изготовления спиртовой настойки на основе измельчённых листьев карри. Определены оптимальные параметры изготовления спиртовой настойки: соотношение спирт 70%/измельченные сухие листья Карри 5/1, коэффициент поглощения 1,3, продолжительность 7 суток

Self-assessment and perception of life perspective in youth

The article is devoted to the study of self-esteem and perception of life perspectives in adolescenceСтатья посвящена исследованию самооценки и восприятия жизненной перспективы в юношеском возраст

Features of antifungal therapy during long-lasting infectious process: a clinical case of fungal keratitis and profile of antifungal sensitivity based on assessing biofilm formation

Among infectious diseases, opportunistic mycoses hold a special place. There has been accumulating a lot of evidence regarding the clinical and epidemiological aspects of infection caused by Fusarium spp., which global incidence rate among microbial keratitis ranges from 2 to 40% depending on the geographical location of the country. Colonizing mucous membranes, fungi can exist not only in the form of plankton, but form biofilms after surface attachment, which leads to elevated resistance to multiple antifungal agents. Here we describe a clinical case of fungal keratitis due to Fusarium solani by determining profile of the antifungal sensitivity for isolated fungal strains, by taking into account their potential for biofilm formation. We used an F. solani culture isolated from the patient as well as F. solani test culture obtained from the Russian National Collection of Microorganisms. While determining the sensitivity of fungal planktonic cultures to antifungal agents from the azole group (fluconazole, voriconazole), amphotericin B and terbinafine, it was revealed that antimycotics amphotericin B and voriconazole exerted a marked antifungal activity against clinical isolate, whereas the plankton F. solani test culture was more sensitive to all groups of antifungal agents. Due to a long-lasting progressive course of the infectious process and the high biofilm-forming ability of the clinical strain F. solani, the activity of antifungal agents on biofilm cells was modeled and examined in vitro. It was shown that regarding to the fungal biofilms, value of the minimally inhibitory concentration exceeded those for planktonic cultures by 100-fold. The mechanisms of action for antifungal agents on vital parameters of fungal cell structures were analyzed by using confocal laser scanning microscopy after staining samples with propidium iodide and acridine orange for 15 min to detect changes between intact and damaged cell surface. It was found that within the biofilm fungal cells preserved viability even after exposure to high concentrations of antifungals. In addition, despite the fungicidal drug activity at substantial concentrations acting on the biofilm cell membrane, the cell nuclei remained viable. Owing to the presence ot the mechanism of resistance in mycelial fungi shown in the study, it is necessary to take into account and investigate characteristics of biofilms in terms of drug sensitivity that will allow to optimize a choice of antimicrobial therapy

2-AZINYL QUINAZOLINES: SYNTHESIS AND PHOTOPHYSICAL PROPERTIES

This work was supported by the Russian Scientific Foundation (project 22-23-00006)

An Effective Synthetic Approach to of 2-([5'-Aryl-2,2'-bipyridin]-6-yl)-5-aryl-1,3,4-oxadiazoles

Abstract: A convenient synthetic approach to 2-(2,2'-bipyridin-6-yl)-1,3,4-oxadiazole derivatives is proposed, which involves the preparation of 5-aryl-2,2'-bipyridine-6-carboxylic acid esters by the “1,2,4-triazine” methodology and the subsequent construction of the 1,3,4-oxadiazole ring via the modification of the ester group. © 2023, The Author(s).Russian Science Foundation, RSF: 18-73-10119-PThe work was financially supported by the Russian Science Foundation (project no. 18-73-10119-P)